scholarly journals Tailoring the hydrophobicity of graphene for its use as nanopores for DNA translocation

2013 ◽  
Vol 4 (1) ◽  
Author(s):  
Grégory F. Schneider ◽  
Qiang Xu ◽  
Susanne Hage ◽  
Stephanie Luik ◽  
Johannes N. H. Spoor ◽  
...  
Keyword(s):  
Dna Translocation

scholarly journals Controlling DNA Translocation Through Solid-state Nanopores

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Zhishan Yuan ◽  
Youming Liu ◽  
Min Dai ◽  
Xin Yi ◽  
Chengyong Wang
Keyword(s):  
Solid State ◽  
Dna Translocation

scholarly journals Sophisticated Conversations between Chromatin and Chromatin Remodelers, and Dissonances in Cancer

2021 ◽  
Vol 22 (11) ◽  
pp. 5578
Author(s):  
Cedric R. Clapier
Keyword(s):  
Gene Expression ◽  
Regulation Of Gene Expression ◽  
Structural Diversity ◽  
Nucleosome Positioning ◽  
Basic Mechanism ◽  
Progressive Increase ◽  
Chromatin Organization ◽  
Dna Translocation ◽  
Dynamic Regulation ◽  
Cooperative Action

The establishment and maintenance of genome packaging into chromatin contribute to define specific cellular identity and function. Dynamic regulation of chromatin organization and nucleosome positioning are critical to all DNA transactions—in particular, the regulation of gene expression—and involve the cooperative action of sequence-specific DNA-binding factors, histone modifying enzymes, and remodelers. Remodelers are molecular machines that generate various chromatin landscapes, adjust nucleosome positioning, and alter DNA accessibility by using ATP binding and hydrolysis to perform DNA translocation, which is highly regulated through sophisticated structural and functional conversations with nucleosomes. In this review, I first present the functional and structural diversity of remodelers, while emphasizing the basic mechanism of DNA translocation, the common regulatory aspects, and the hand-in-hand progressive increase in complexity of the regulatory conversations between remodelers and nucleosomes that accompanies the increase in challenges of remodeling processes. Next, I examine how, through nucleosome positioning, remodelers guide the regulation of gene expression. Finally, I explore various aspects of how alterations/mutations in remodelers introduce dissonance into the conversations between remodelers and nucleosomes, modify chromatin organization, and contribute to oncogenesis.

scholarly journals DNA Translocation through Graphene Nanopores

Nano Letters ◽  
2010 ◽  
Vol 10 (8) ◽  
pp. 3163-3167 ◽  
Author(s):  
Grégory F. Schneider ◽  
Stefan W. Kowalczyk ◽  
Victor E. Calado ◽  
Grégory Pandraud ◽  
Henny W. Zandbergen ◽  
...  
Keyword(s):  
Dna Translocation

scholarly journals Zero-Mode Waveguide Detection of Flow-Driven DNA Translocation through Nanopores

2014 ◽  
Vol 113 (2) ◽  
Author(s):  
Thomas Auger ◽  
Jérôme Mathé ◽  
Virgile Viasnoff ◽  
Gaëlle Charron ◽  
Jean-Marc Di Meglio ◽  
...  
Keyword(s):  
Zero Mode ◽  
Dna Translocation

Sequence-Directed DNA Translocation by Purified FtsK

Science ◽  
2005 ◽  
Vol 307 (5709) ◽  
pp. 586-590 ◽  
Author(s):  
P. J. Pease
Keyword(s):  
Dna Translocation
Sign in / Sign up

Export Citation Format

Share Document