scholarly journals Quantitative experimental determination of site-specific magnetic structures by transmitted electrons

2013 ◽  
Vol 4 (1) ◽  
Author(s):  
Z.Q. Wang ◽  
X.Y. Zhong ◽  
R. Yu ◽  
Z.Y. Cheng ◽  
J. Zhu
eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Laurence Abrami ◽  
Tiziano Dallavilla ◽  
Patrick A Sandoz ◽  
Mustafa Demir ◽  
Béatrice Kunz ◽  
...  

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key proteins of the endoplasmic reticulum, is controlled by an upstream palmitoyltransferase, ZDHHC16, revealing the first palmitoylation cascade. The combination of site specific mutagenesis of the three ZDHHC6 palmitoylation sites, experimental determination of kinetic parameters and data-driven mathematical modelling allowed us to obtain detailed information on the eight differentially palmitoylated ZDHHC6 species. We found that species rapidly interconvert through the action of ZDHHC16 and the Acyl Protein Thioesterase APT2, that each species varies in terms of turnover rate and activity, altogether allowing the cell to robustly tune its ZDHHC6 activity.


2003 ◽  
Vol 88 (7) ◽  
pp. 1060-1072 ◽  
Author(s):  
Thráinn Fridriksson ◽  
J. William Carey ◽  
David L. Bish ◽  
Philip S. Neuhoff ◽  
Dennis K. Bird

Author(s):  
Jessica A. Onwuzuruike ◽  
Maruf A. Aminu

The nature of renewable energy resources makes it necessary to perform site-specific resource assessment in order to achieve fairly accurate estimate of energy harvest so as to meet requirements of energy consumption and storage. Available design tools are based largely on remote modeling and estimation of site’s resource potentials. These design tools provide analytical value of the panel generation factor which may not represent the true value. The panel generation factor is used for design of solar photovoltaic systems. This paper reports on the panel generation factor obtained from experimental determination of its value for Apo Area of the Federal Capital Territory in Nigeria. The value of the panel generation factor obtained experimentally for Apo Area is 3.625. The panel generation factor reported in literature for tropical climate of Apo is 3.596. The value obtained for the experimentally determined panel generation factor represents a deviation of 0.88% in comparison with the value reported in literature, validating the value obtained experimentally. The site-specific requirement of renewable energy deployment is indicative of the usefulness of this experimentally determined panel generation factor.


2017 ◽  
Author(s):  
Laurence Abrami ◽  
Tiziano Dallavilla ◽  
Patrick A. Sandoz ◽  
Mustafa Demir ◽  
Béatrice Kunz ◽  
...  

ABSTRACTS-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC family of palmitoyltransferases is very limited. Here we show that mammalian DHHC6, which modifies key proteins of the endoplasmic reticulum, is controlled by an upstream palmitoyltransferase, DHHC16, revealing the first palmitoylation cascade. Combination of site specific mutagenesis of the three DHHC6 palmitoylation sites, experimental determination of kinetic parameters and data-driven mathematical modelling allowed us to obtain detailed information on the 8 differentially palmitoylated DHHC6 species. We found that species rapidly interconvert through the action of DHHC16 and the Acyl Protein Thioesterase APT2, that each species varies in terms of turnover rate and activity, altogether allowing the cell to robustly tune its DHHC6 activity.


1999 ◽  
Vol 96 (6) ◽  
pp. 1111-1116 ◽  
Author(s):  
E. Falcon ◽  
S. Fauve ◽  
C. Laroche

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