scholarly journals Phase separation drives heterochromatin domain formation

Nature ◽  
2017 ◽  
Vol 547 (7662) ◽  
pp. 241-245 ◽  
Author(s):  
Amy R. Strom ◽  
Alexander V. Emelyanov ◽  
Mustafa Mir ◽  
Dmitry V. Fyodorov ◽  
Xavier Darzacq ◽  
...  
Keyword(s):  
Phase Separation ◽  
Domain Formation ◽  
Heterochromatin Domain

scholarly journals Phase Separation Drives Heterochromatin Domain Formation

2018 ◽  
Vol 114 (3) ◽  
pp. 445a ◽  
Author(s):  
Amy R. Strom ◽  
Alexander V. Emelyanov ◽  
Mustafa R. Mir ◽  
Dmitry V. Fyodorov ◽  
Xavier R. Darzacq ◽  
...  
Keyword(s):  
Phase Separation ◽  
Domain Formation ◽  
Heterochromatin Domain

Domain formation on curved membranes: phase separation or Turing patterns?

Soft Matter ◽  
2013 ◽  
Vol 9 (39) ◽  
pp. 9311 ◽  
Author(s):  
E. Orlandini ◽  
D. Marenduzzo ◽  
A. B. Goryachev
Keyword(s):  
Phase Separation ◽  
Turing Patterns ◽  
Domain Formation ◽  
Curved Membranes

scholarly journals Can adding oil control domain formation in binary amphiphile bilayers?

Soft Matter ◽  
2014 ◽  
Vol 10 (40) ◽  
pp. 7925-7931
Author(s):  
Martin J. Greenall ◽  
Carlos M. Marques
Keyword(s):  
Phase Separation ◽  
Domain Formation ◽  
Control Phase

The addition of oil to a mixed membrane is predicted to smooth the interface between the domains and could control phase separation.

Phase Separation and Fractal Domain Formation in Phospholipid/Diacetylene-Supported Lipid Bilayers

Langmuir ◽  
2007 ◽  
Vol 23 (21) ◽  
pp. 10661-10671 ◽  
Author(s):  
Jose M. Moran-Mirabal ◽  
Donald M. Aubrecht ◽  
Harold G. Craighead
Keyword(s):  
Phase Separation ◽  
Lipid Bilayers ◽  
Supported Lipid Bilayers ◽  
Domain Formation ◽  
Fractal Domain

scholarly journals The Effect of Transmembrane Protein Shape on Surrounding Lipid Domain Formation by Wetting

Biomolecules ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 729 ◽  
Author(s):  
Molotkovsky ◽  
Galimzyanov ◽  
Batishchev ◽  
Akimov
Keyword(s):  
Phase Separation ◽  
Transmembrane Protein ◽  
Lipid Phase ◽  
Lipid Domains ◽  
Domain Formation ◽  
Cellular Membranes ◽  
Lipid Domain ◽  
Liquid Ordered ◽  
Lipid Environment ◽  
Protein Shape

Signal transduction through cellular membranes requires the highly specific and coordinated work of specialized proteins. Proper functioning of these proteins is provided by an interplay between them and the lipid environment. Liquid-ordered lipid domains are believed to be important players here, however, it is still unclear whether conditions for a phase separation required for lipid domain formation exist in cellular membranes. Moreover, membrane leaflets are compositionally asymmetric, that could be an obstacle for the formation of symmetric domains spanning the lipid bilayer. We theoretically show that the presence of protein in the membrane leads to the formation of a stable liquid-ordered lipid phase around it by the mechanism of protein wetting by lipids, even in the absence of conditions necessary for the global phase separation in the membrane. Moreover, we show that protein shape plays a crucial role in this process, and protein conformational rearrangement can lead to changes in the size and characteristics of surrounding lipid domains.

scholarly journals Phase-Separation and Domain-Formation in Cholesterol-Sphingomyelin Mixture: Pulse-EPR Oxygen Probing

2011 ◽  
Vol 101 (4) ◽  
pp. 837-846 ◽  
Author(s):  
Laxman Mainali ◽  
Marija Raguz ◽  
Witold K. Subczynski
Keyword(s):  
Phase Separation ◽  
Domain Formation ◽  
Pulse Epr
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