scholarly journals Erratum: Corrigendum: Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Nature ◽  
2015 ◽  
Vol 526 (7571) ◽  
pp. 144-144 ◽  
Author(s):  
Sandra Schoors ◽  
Ulrike Bruning ◽  
Rindert Missiaen ◽  
Karla C. S. Queiroz ◽  
Gitte Borgers ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Fatty Acid ◽  
Fatty Acid Carbon

scholarly journals Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Nature ◽  
2015 ◽  
Vol 520 (7546) ◽  
pp. 192-197 ◽  
Author(s):  
Sandra Schoors ◽  
Ulrike Bruning ◽  
Rindert Missiaen ◽  
Karla C. S. Queiroz ◽  
Gitte Borgers ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Fatty Acid ◽  
Fatty Acid Carbon

scholarly journals The Conversion of Glutamate Carbon to Fatty Acid Carbon via Citrate

1964 ◽  
Vol 239 (5) ◽  
pp. 1305-1309
Author(s):  
J. Madsen ◽  
S. Abraham ◽  
I.L. Chaikoff
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Carbon

scholarly journals Fatty acid transporter expression and regulation is impaired in placental macrovascular endothelial cells in obese women

2017 ◽  
Vol 32 (6) ◽  
pp. 971-978 ◽  
Author(s):  
Xiaohua Yang ◽  
Patricia Glazebrook ◽  
Geraldine C. Ranasinghe ◽  
Maricela Haghiac ◽  
Virtu Calabuig-Navarro ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Fatty Acid ◽  
Obese Women ◽  
Fatty Acid Transporter ◽  
Acid Transporter ◽  
Transporter Expression

scholarly journals Acetate represents a major product of heptanoate and octanoate β-oxidation in hepatocytes isolated from neonatal piglets

1996 ◽  
Vol 318 (1) ◽  
pp. 235-240 ◽  
Author(s):  
Xi LIN ◽  
Sean H. ADAMS ◽  
Jack ODLE
Keyword(s):  
Fatty Acid ◽  
Organic Acids ◽  
Chain Length ◽  
Ketone Bodies ◽  
Krebs Cycle ◽  
Major Product ◽  
Carbon Accounting ◽  
Minor Amount ◽  
Fatty Acid Carbon ◽  
Carboxyl Carbon

An experiment was conducted to explore the nature of the radiolabel distribution in acid-soluble products (ASPs) resulting from the oxidation of [1-14C]C7:0 or C8:0 by isolated piglet hepatocytes. The differences between odd and even chain-length and the impacts of valproate and malonate upon the rate of β-oxidation and ASP characteristics were tested. A minor amount of fatty acid carboxyl carbon (⩽ 10% of organic acids identified by radio-HPLC) accumulated in ketone bodies regardless of chain-length or inhibitor used. In all cases, acetate represented the major reservoir of carboxyl carbon, accounting for 60–70% of radiolabel in identified organic acids. Cells given [1-14C]C7:0 accumulated 85% more carboxyl carbon in Krebs cycle intermediates when compared with C8:0, while accumulation in acetate was unaffected. The results are consistent with the hypothesis that anaplerosis from odd-carbon fatty acids affects the oxidative fate of fatty acid carbon. The piglet appears unique in that non-ketogenic routes of fatty acid carbon flow (i.e. acetogenesis) predominate in the liver of this species.

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