scholarly journals Gene regulatory logic of dopamine neuron differentiation

Nature ◽  
2009 ◽  
Vol 458 (7240) ◽  
pp. 885-889 ◽  
Author(s):  
Nuria Flames ◽  
Oliver Hobert
Keyword(s):  
Dopamine Neuron ◽  
Neuron Differentiation ◽  
Gene Regulatory

scholarly journals Proneural bHLH neurogenin 2 differentially regulates Nurr1-induced dopamine neuron differentiation in rat and mouse neural precursor cells in vitro

FEBS Letters ◽  
2008 ◽  
Vol 582 (5) ◽  
pp. 537-542 ◽  
Author(s):  
Chang-Hwan Park ◽  
Jin Sun Kang ◽  
Eun-Hye Yoon ◽  
Jae-Won Shim ◽  
Haeyoung Suh-Kim ◽  
...  
Keyword(s):  
Precursor Cells ◽  
Dopamine Neuron ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Neuron Differentiation

scholarly journals Vitamin C Facilitates Dopamine Neuron Differentiation in Fetal Midbrain Through TET1- and JMJD3-Dependent Epigenetic Control Manner

Stem Cells ◽  
2015 ◽  
Vol 33 (4) ◽  
pp. 1320-1332 ◽  
Author(s):  
Xi-Biao He ◽  
Mirang Kim ◽  
Seon-Young Kim ◽  
Sang-Hoon Yi ◽  
Yong-Hee Rhee ◽  
...  
Keyword(s):  
Vitamin C ◽  
Dopamine Neuron ◽  
Control Manner ◽  
Neuron Differentiation ◽  
Epigenetic Control

scholarly journals Stress and odorant receptor feedback during a critical period after hatching regulates olfactory sensory neuron differentiation in Drosophila

PLoS Biology ◽  
2021 ◽  
Vol 19 (4) ◽  
pp. e3001101
Author(s):  
Shadi Jafari ◽  
Johan Henriksson ◽  
Hua Yan ◽  
Mattias Alenius
Keyword(s):  
Sensory Neuron ◽  
Critical Period ◽  
Odorant Receptor ◽  
Pupal Stage ◽  
Feedback Mechanism ◽  
Olfactory Sensory Neuron ◽  
Regulatory State ◽  
Neuron Differentiation ◽  
Heterochromatin Formation ◽  
Gene Regulatory

Here, we reveal that the regulation of Drosophila odorant receptor (OR) expression during the pupal stage is permissive and imprecise. We found that directly after hatching an OR feedback mechanism both directs and refines OR expression. We demonstrate that, as in mice, dLsd1 and Su(var)3-9 balance heterochromatin formation to direct OR expression. We show that the expressed OR induces dLsd1 and Su(var)3-9 expression, linking OR level and possibly function to OR expression. OR expression refinement shows a restricted duration, suggesting that a gene regulatory critical period brings olfactory sensory neuron differentiation to an end. Consistent with a change in differentiation, stress during the critical period represses dLsd1 and Su(var)3-9 expression and makes the early permissive OR expression permanent. This induced permissive gene regulatory state makes OR expression resilient to stress later in life. Hence, during a critical period OR feedback, similar to in mouse OR selection, defines adult OR expression in Drosophila.

scholarly journals Thyroid hormones and their derivatives promote dopamine neuron differentiation

IBRO Reports ◽  
2019 ◽  
Vol 6 ◽  
pp. S337
Author(s):  
Eun-Hye Lee ◽  
Sang-Mi Kim ◽  
Chang-Hwan Park
Keyword(s):  
Thyroid Hormones ◽  
Dopamine Neuron ◽  
Neuron Differentiation

scholarly journals Prolonged Membrane Depolarization Enhances Midbrain Dopamine Neuron Differentiation via Epigenetic Histone Modifications

Stem Cells ◽  
2011 ◽  
Vol 29 (11) ◽  
pp. 1861-1873 ◽  
Author(s):  
Xi-Biao He ◽  
Sang-Hoon Yi ◽  
Yong-Hee Rhee ◽  
Hyemin Kim ◽  
Yong-Mahn Han ◽  
...  
Keyword(s):  
Histone Modifications ◽  
Membrane Depolarization ◽  
Dopamine Neuron ◽  
Neuron Differentiation ◽  
Midbrain Dopamine

scholarly journals Histamine Modulates Midbrain Dopamine Neuron Differentiation Through the Regulation of Epigenetic Marks

2019 ◽  
Vol 13 ◽  
Author(s):  
Fernanda Vargas-Romero ◽  
Rodrigo González-Barrios ◽  
Lissania Guerra-Calderas ◽  
Itzel Escobedo-Avila ◽  
Daniel Cortés-Pérez ◽  
...  
Keyword(s):  
Dopamine Neuron ◽  
Neuron Differentiation ◽  
Epigenetic Marks ◽  
Midbrain Dopamine
Sign in / Sign up

Export Citation Format

Share Document