scholarly journals Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma

2006 ◽  
Vol 19 (5) ◽  
pp. 659-668 ◽  
Author(s):  
Stephen H Olsen ◽  
Dafydd G Thomas ◽  
David R Lucas
Keyword(s):  
Cluster Analysis ◽  
Peripheral Nerve ◽  
Synovial Sarcoma ◽  
Ewing Sarcoma ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Malignant Peripheral Nerve Sheath Tumor With a t(X;18)

2000 ◽  
Vol 124 (6) ◽  
pp. 864-867 ◽  
Author(s):  
Russell Vang ◽  
David A. Biddle ◽  
Wilbur R. Harrison ◽  
Kent Heck ◽  
Linda D. Cooley
Keyword(s):  
Peripheral Nerve ◽  
Synovial Sarcoma ◽  
Chromosomal Translocation ◽  
Collagen Type Iv ◽  
Variant Form ◽  
Nerve Sheath Tumor ◽  
Electron Microscopic ◽  
Peripheral Nerve Sheath Tumor ◽  
Type Iv ◽  
Nerve Sheath

Abstract We describe an ankle tumor arising in a 16-year-old girl. The tumor demonstrated histology typical of a malignant peripheral nerve sheath tumor (MPNST), but exhibited a variant form of the (X;18) translocation associated with synovial sarcoma. Immunohistochemical stains were positive for vimentin, CD57, collagen type IV, and Bcl-2. Routine and molecular cytogenetic studies showed an unbalanced 3-way chromosomal translocation that involved chromosomes X, 18, and 1. Electron microscopic findings were noncontributory. This unusual tumor raises the following questions and possibilities: (1) As the t(X;18) suggests, could this tumor be a monophasic synovial sarcoma with the histologic features of an MPNST? (2) Or, as the histology suggests, is this tumor an MPNST that has a t(X;18)? (3) Finally, could MPNST histology, a t(X;18), and no defining immunohistochemical or electron microscopic features represent an as yet unrecognized part of a spectrum that spans from synovial sarcoma to MPNST or other spindle cell tumors?

Ewing sarcoma mimicking a peripheral nerve sheath tumor

2010 ◽  
Vol 17 (10) ◽  
pp. 1317-1319 ◽  
Author(s):  
B.D. Mitchell ◽  
B.D. Fox ◽  
A. Viswanathan ◽  
A.H. Mitchell ◽  
S.Z. Powell ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Ewing Sarcoma ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Synovial sarcoma mimicking benign peripheral nerve sheath tumor

2017 ◽  
Vol 46 (11) ◽  
pp. 1463-1468 ◽  
Author(s):  
Ana B. Larque ◽  
Miriam A. Bredella ◽  
G. Petur Nielsen ◽  
Ivan Chebib
Keyword(s):  
Peripheral Nerve ◽  
Synovial Sarcoma ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath
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