scholarly journals HMGA proteins in malignant peripheral nerve sheath tumor and synovial sarcoma: preferential expression of HMGA2 in malignant peripheral nerve sheath tumor

2005 ◽  
Vol 18 (11) ◽  
pp. 1519-1526 ◽  
Author(s):  
Pei Hui ◽  
Ning Li ◽  
Chaline Johnson ◽  
Ivo De Wever ◽  
Raf Sciot ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Synovial Sarcoma ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Preferential Expression ◽  
Nerve Sheath

Malignant Peripheral Nerve Sheath Tumor With a t(X;18)

2000 ◽  
Vol 124 (6) ◽  
pp. 864-867 ◽  
Author(s):  
Russell Vang ◽  
David A. Biddle ◽  
Wilbur R. Harrison ◽  
Kent Heck ◽  
Linda D. Cooley
Keyword(s):  
Peripheral Nerve ◽  
Synovial Sarcoma ◽  
Chromosomal Translocation ◽  
Collagen Type Iv ◽  
Variant Form ◽  
Nerve Sheath Tumor ◽  
Electron Microscopic ◽  
Peripheral Nerve Sheath Tumor ◽  
Type Iv ◽  
Nerve Sheath

Abstract We describe an ankle tumor arising in a 16-year-old girl. The tumor demonstrated histology typical of a malignant peripheral nerve sheath tumor (MPNST), but exhibited a variant form of the (X;18) translocation associated with synovial sarcoma. Immunohistochemical stains were positive for vimentin, CD57, collagen type IV, and Bcl-2. Routine and molecular cytogenetic studies showed an unbalanced 3-way chromosomal translocation that involved chromosomes X, 18, and 1. Electron microscopic findings were noncontributory. This unusual tumor raises the following questions and possibilities: (1) As the t(X;18) suggests, could this tumor be a monophasic synovial sarcoma with the histologic features of an MPNST? (2) Or, as the histology suggests, is this tumor an MPNST that has a t(X;18)? (3) Finally, could MPNST histology, a t(X;18), and no defining immunohistochemical or electron microscopic features represent an as yet unrecognized part of a spectrum that spans from synovial sarcoma to MPNST or other spindle cell tumors?

Synovial sarcoma mimicking benign peripheral nerve sheath tumor

2017 ◽  
Vol 46 (11) ◽  
pp. 1463-1468 ◽  
Author(s):  
Ana B. Larque ◽  
Miriam A. Bredella ◽  
G. Petur Nielsen ◽  
Ivan Chebib
Keyword(s):  
Peripheral Nerve ◽  
Synovial Sarcoma ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

Malignant Peripheral Nerve Sheath Tumor Arising from a Solitary Neurofibroma in a Patient without Neurofibromatosis Type 1

2016 ◽  
Vol 78 (5) ◽  
pp. 516-521
Author(s):  
Fumihisa SAWADA ◽  
Eiichi MAKINO ◽  
Takenobu YAMAMOTO ◽  
Ryo TANAKA ◽  
Yutaka FUJIWARA ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Solitary Neurofibroma
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