scholarly journals p63 Immunohistochemistry in the distinction of adenoid cystic carcinoma from basaloid squamous cell carcinoma

2004 ◽  
Vol 18 (5) ◽  
pp. 645-650 ◽  
Author(s):  
Patrick Emanuel ◽  
Beverly Wang ◽  
Maoxin Wu ◽  
David E Burstein
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Adenoid Cystic Carcinoma ◽  
Squamous Cell ◽  
Basaloid Squamous Cell Carcinoma ◽  
Adenoid Cystic ◽  
Basaloid Squamous

Basaloid squamous cell carcinoma with adenoid cystic‐like features of the head and neck region: A report of two cases

2020 ◽  
Vol 70 (10) ◽  
pp. 767-774
Author(s):  
Kimihide Kusafuka ◽  
Haruna Yagi ◽  
Satoshi Baba ◽  
Hiroshi Inagaki ◽  
Chinatsu Tsuchiya ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Region ◽  
Basaloid Squamous Cell Carcinoma ◽  
Head And Neck Region ◽  
Adenoid Cystic ◽  
Basaloid Squamous

Basaloid Squamous Cell Carcinoma of the Esophagus With or Without Adenoid Cystic Features

2004 ◽  
Vol 128 (10) ◽  
pp. 1124-1130 ◽  
Author(s):  
Tie-Jun Li ◽  
Yong-Xin Zhang ◽  
Julie Wen ◽  
Daniel F. Cowan ◽  
John Hart ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Smooth Muscle ◽  
Cell Carcinoma ◽  
Tumor Cells ◽  
Squamous Cell ◽  
Smooth Muscle Actin ◽  
Basaloid Squamous Cell Carcinoma ◽  
Muscle Actin ◽  
Adenoid Cystic ◽  
Basaloid Squamous

Abstract Context.—Basaloid squamous cell carcinoma (BSCC) of the esophagus is a rare malignant tumor that morphologically could bear some resemblance to adenoid cystic carcinoma (ACC) originating from salivary glands. Objective.—The purpose of this study is to describe the histologic, immunohistochemical, and ultrastructural findings of BSCCs of the esophagus, with an emphasis on comparing tumors with or without adenoid cystic features. Design.—We reviewed 239 cases of primary esophageal carcinoma and detected 12 cases (5%) of BSCC. The light and electron microscopic findings and immunocytochemical localization of various antigens, including cytokeratins (AE1, AE3), carcinoembryonic antigen, epithelial membrane antigen, S100, smooth muscle actin, and p53, were examined in these BSCC cases. Results.—Histologically, all BSCCs were composed of solid lobules or nests of basaloid cells with well-demarcated outlines surrounded by a fibrous stroma. Seven of 12 tumors showed areas of ACC-like features, that is, cribriform-like pseudoglandular lumina formation and hyaline material surrounding the tumor nests, whereas the remaining 5 tumors were apparently pure basaloid carcinomas. These 2 groups of tumors were histologically and immunohistochemically identical in many aspects, namely, high-grade nuclei of the tumor cells with frequent mitoses, abundant comedo-type necrosis, focal areas of concomitant squamous differentiation, consistent immunoreactivity for cytokeratins, and poor or absent staining for S100 and smooth muscle actin. Ultrastructurally, the basaloid tumor cells exhibited relatively undifferentiated cellular characteristics and undeveloped cell organelles. Conclusion.—Basaloid squamous cell carcinomas of the esophagus frequently have an intimate association with ACC-like patterns, but their histologic, immunocytochemical, and ultrastructural features correspond more to poorly differentiated squamous cell carcinoma than to salivary gland ACC. This distinction is important because genuine ACC is much less aggressive than BSCC.

scholarly journals Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Kumiko Sekiguchi ◽  
Takeshi Matsutani ◽  
Tsutomu Nomura ◽  
Nobutoshi Hagiwara ◽  
Akihisa Matsuda ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Pulmonary Metastasectomy ◽  
Basaloid Squamous Cell Carcinoma ◽  
Basaloid Squamous

scholarly journals Cutaneous metastasis from esophageal basaloid squamous cell carcinoma: A case report

2021 ◽  
Vol 80 ◽  
pp. 105621
Author(s):  
Fumitaka Endo ◽  
Yuji Akiyama ◽  
Masazumi Onishi ◽  
Noriyuki Uesugi ◽  
Tamotsu Sugai ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Metastasis ◽  
Basaloid Squamous Cell Carcinoma ◽  
Basaloid Squamous

Mucosal Adenoid Squamous Cell Carcinoma of the Head and Neck

1996 ◽  
Vol 105 (5) ◽  
pp. 409-413 ◽  
Author(s):  
Alfio Ferlito ◽  
Kenneth O. Devaney ◽  
Christopher M. Milroy ◽  
Alessandra Rinaldo ◽  
Antonino Carbone
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Adenosquamous Carcinoma ◽  
Neck Region ◽  
Metastatic Adenocarcinoma ◽  
Head And Neck Region ◽  
Adenoid Cystic ◽  
Basaloid Squamous

Adenoid squamous cell carcinoma is an uncommon variant of squamous cell carcinoma. The lesion is histologically distinctive and it is usually localized on the skin of the head and neck region; it only rarely involves the mucosal sites. The differential diagnoses include adenosquamous carcinoma, adenoid cystic carcinoma, mucoepidermoid carcinoma, basaloid squamous cell carcinoma, and metastatic adenocarcinoma. Surgery is the treatment of choice. The biologic behavior of this neoplasm is more aggressive when it involves mucosal areas, and the prognosis seems worse than that of conventional squamous cell carcinoma.

Sign in / Sign up

Export Citation Format

Share Document