scholarly journals Searching for mammary analog secretory carcinoma of salivary gland among its mimics

2013 ◽  
Vol 27 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Andre Pinto ◽  
Vania Nosé ◽  
Claudia Rojas ◽  
Yao-Shan Fan ◽  
Carmen Gomez-Fernandez
Keyword(s):  
Salivary Gland ◽  
Secretory Carcinoma ◽  
Mammary Analog Secretory Carcinoma

scholarly journals Erratum: Searching for mammary analog secretory carcinoma of salivary gland among its mimics

2014 ◽  
Vol 27 (6) ◽  
pp. 918-918 ◽  
Author(s):  
Andre Pinto ◽  
Vania Nosé ◽  
Claudia Rojas ◽  
Yao-Shan Fan ◽  
Carmen Gomez-Fernandez
Keyword(s):  
Salivary Gland ◽  
Secretory Carcinoma ◽  
Mammary Analog Secretory Carcinoma

Mammary Analog Secretory Carcinoma of Salivary Gland Origin With the ETV6 Gene Rearrangement by FISH

2012 ◽  
Vol 36 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Ashton Connor ◽  
Bayardo Perez-Ordoñez ◽  
Mary Shago ◽  
Alena Skálová ◽  
Ilan Weinreb
Keyword(s):  
Salivary Gland ◽  
Gene Rearrangement ◽  
Secretory Carcinoma ◽  
Mammary Analog Secretory Carcinoma

scholarly journals Secretory Carcinoma: A Silent Mass Increasing in the Parotid Gland

2020 ◽  
Vol 8 (C) ◽  
pp. 191-194
Author(s):  
Cheng-Chieh Lu ◽  
Chien-Jui Cheng ◽  
Yu-Chien Kao ◽  
Mei-Chien Chen
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Regional Lymph Node ◽  
Surgical Excision ◽  
Low Grade ◽  
Secretory Carcinoma ◽  
Unique Case ◽  
Complete Surgical Excision ◽  
Immunohistochemical Studies ◽  
Mammary Analog Secretory Carcinoma

BACKGROUND: Secretory carcinoma (SC) of the salivary gland, also known as mammary analog secretory carcinoma, is a rare tumor in the parotid gland. This kind of tumor is characterized by generally indolent clinical behavior and expression of a break in the ETV6 gene. CASE REPORT: We present a unique case of secretory carcinoma and show its favorable prognoses. CONCLUSION: Secretory carcinoma of the salivary gland is a low-grade carcinoma with a favorable prognosis. It has low regional lymph node and distant metastasis potential. Due to the possibility of misdiagnosis, immunohistochemical studies and FISH are suggested. The most effective treatment is complete surgical excision with negative surgical margins.

scholarly journals The cytopathologic features of mammary analog secretory carcinoma and its mimics

CytoJournal ◽  
2014 ◽  
Vol 11 ◽  
pp. 24 ◽  
Author(s):  
T. Danielle Samulski ◽  
Virginia A. LiVolsi ◽  
Zubair Baloch
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Needle Aspiration ◽  
Definite Diagnosis ◽  
Secretory Carcinoma ◽  
Warthin Tumor ◽  
Fine Needle ◽  
Monomorphic Population ◽  
Mammary Analog Secretory Carcinoma ◽  
Foamy Cytoplasm

Mammary Analogue Secretory Carcinoma (MASC) is a newly recognized neoplasm of the salivary gland, first described in 2010. This tumor harbors a unique translocation, t(12;15)(p13;q25) that results in the fusion of ETV6 with NTRK3 which produces a transformative chimeric tyrosine kinase. To date, few cases of MASC sampled by fine needle aspiration have been reported. Cytologically, MASC can be confused with other oncocytic salivary gland tumors, including Warthin-tumor, acinic cell carcinoma (AciCC) and mucoepidermoid carcinoma. It is characterized by a monomorphic population of lesional cells with round nuclei, prominent nucleoli and abundant, eosinophilic foamy cytoplasm; forming papillary groups with transgressing vessels. Though, based on cytomorphology alone, the definite diagnosis can be challenging, in conjunction with available clinical clues (i.e. male patient, extra-parotid site) MASC should be included in the differential diagnosis of FNA specimens diagnosed as oncocytic salivary gland neoplasms or suspicious for AciCC. Here we present a case of MASC with FNA sampling at our institution.

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