scholarly journals Frozen section analysis of margins for head and neck tumor resections: reduction of sampling errors with a third histologic level

2011 ◽  
Vol 24 (5) ◽  
pp. 665-670 ◽  
Author(s):  
Stephen M Olson ◽  
Mohammad Hussaini ◽  
James S Lewis
Keyword(s):  
Head And Neck ◽  
Frozen Section ◽  
Head And Neck Tumor ◽  
Sampling Errors ◽  
Neck Tumor ◽  
Frozen Section Analysis ◽  
Section Analysis

scholarly journals Reliability of Frozen Section Analysis in Transoral Laser Microsurgery of Upper Aerodigestive Tract Advanced Malignant Tumors

2011 ◽  
Vol 1 (2) ◽  
pp. 44-46 ◽  
Author(s):  
Nayla Matar ◽  
Georges Lawson ◽  
Marc Remacle ◽  
Marie-Cécile Nollevaux ◽  
Monique Delos ◽  
...  
Keyword(s):  
Head And Neck ◽  
Frozen Section ◽  
Aerodigestive Tract ◽  
Surgical Margins ◽  
Transoral Laser Microsurgery ◽  
Upper Aerodigestive Tract ◽  
Laser Microsurgery ◽  
Fixed Tissue ◽  
Frozen Section Analysis ◽  
Section Analysis

ABSTRACT Objective Transoral laser microsurgery (TLM) for endoscopic excision of head and neck cancers of the upper aerodigestive tract has become an accepted treatment modality. As in any excision of head and neck tumors, the persistance of tumor at the surgical margins influences the outcome. One of the frequent criticisms of endoscopic resection is that the laser use makes interpretation of the surgical margins difficult due to the thermal effect. The goal of this study is to assess the reliability of frozen section after laser excision in locally advanced tumors. Methods The charts of patients with T2 and T3 tumors, who underwent TLM between January 2000 and 2008, using the CO2 laser AcuBlade system were reviewed. Frozen section margin results obtained during TLM were compared with margins after formalin fixation. Results Sixty-seven patients fulfilled the inclusion criteria. 20 had supraglottic tumors, 22 had oral cavity tumors, 13 had oropharyngeal tumors and 12 had hypopharyngeal tumors. Fifty-nine had no prior treatment, seven had prior radiation therapy and one had prior open surgery. The mean number of frozen margins per surgery was 4. Histological examination on the formalin-fixed tissue confirmed frozen section in 97% of the cases. In 3% of the frozen sections, the diagnosis of invasive carcinoma was missed. None of these patients had significant locoregional disease progression. Conclusion Frozen section analysis of margins is reliable during TLM when performed by an experienced team. It enables a one-stage approach reducing the need of a planned second procedure.

Multimodal nonlinear microscopy of head and neck carcinoma - toward surgery assisting frozen section analysis

Head & Neck ◽  
2016 ◽  
Vol 38 (10) ◽  
pp. 1545-1552 ◽  
Author(s):  
Sandro Heuke ◽  
Olga Chernavskaia ◽  
Thomas Bocklitz ◽  
Fisseha Bekele Legesse ◽  
Tobias Meyer ◽  
...  
Keyword(s):  
Head And Neck ◽  
Frozen Section ◽  
Head And Neck Carcinoma ◽  
Nonlinear Microscopy ◽  
Neck Carcinoma ◽  
Frozen Section Analysis ◽  
Section Analysis

Clinical Study of Head and Neck Tumor Patients Who Underwent Carotid Artery Reconstruction

2013 ◽  
Vol 64 (3) ◽  
pp. 199-205
Author(s):  
Akiteru Maeda ◽  
Shunichi Chitose ◽  
Hirohito Umeno ◽  
Buichiro Shin ◽  
Takeharu Ono ◽  
...  
Keyword(s):  
Clinical Study ◽  
Carotid Artery ◽  
Head And Neck ◽  
Head And Neck Tumor ◽  
Tumor Patients ◽  
Neck Tumor ◽  
Carotid Artery Reconstruction ◽  
Artery Reconstruction

scholarly journals Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks

2017 ◽  
Vol 77 (23) ◽  
pp. 6538-6550 ◽  
Author(s):  
Dylan Z. Kelley ◽  
Emily L. Flam ◽  
Evgeny Izumchenko ◽  
Ludmila V. Danilova ◽  
Hildegard A. Wulf ◽  
...  
Keyword(s):  
Head And Neck ◽  
Integrated Analysis ◽  
Open Chromatin ◽  
Whole Genome ◽  
Head And Neck Tumor ◽  
Rna Seq ◽  
Neck Tumor ◽  
Integration Sites

Bladder-to-bladder metastasis: gallbladder cancer metastasising to the urinary bladder

2021 ◽  
Author(s):  
S Mukherjee ◽  
J Abbaraju ◽  
G Russell ◽  
S Madaan
Keyword(s):  
Urinary Bladder ◽  
Gallbladder Cancer ◽  
Palliative Chemotherapy ◽  
Frozen Section ◽  
Healthy Woman ◽  
Frozen Section Analysis ◽  
Bladder Metastasis ◽  
Distant Spread ◽  
Bladder Mass ◽  
Section Analysis

We report a 48-year-old fit and healthy woman who was incidentally diagnosed to have adenocarcinoma of gallbladder after laparoscopic cholecystectomy. Subsequent imaging showed no evidence of regional or distant spread. She was scheduled for elective laparotomy and resection of gallbladder bed, but during laparotomy frozen section analysis of an incidentally discovered peritoneal deposit confirmed metastasis, so the procedure was abandoned. Thereafter, she received cisplatin and gemcitabine chemotherapy. However, surveillance computed tomography incidentally noted a urinary bladder mass which had not been present before. Transurethral resection of the bladder lesion revealed moderately differentiated adenocarcinoma of urinary bladder. The appearance and immunoprofile of the lesion confirmed metastasis from the primary gallbladder cancer, which has not been documented in the literature to the best of our knowledge. Her disease progressed and she is being challenged with gemcitabine and carboplatin as second-line palliative chemotherapy. She is still alive two years after the initial diagnosis.

690 ROLE OF FROZEN SECTION ANALYSIS DURING RADICAL PROSTATECTOMY A 2,641-CASE EXPERIENCE

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Yasuhiro Kakiuchi ◽  
Bonnie Choy ◽  
Jennifer Gordetsky ◽  
Guan Wu ◽  
Hani Rashid ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Frozen Section ◽  
Frozen Section Analysis ◽  
Section Analysis
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