scholarly journals RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases

2010 ◽  
Vol 24 (2) ◽  
pp. 288-296 ◽  
Author(s):  
Dengfeng Cao ◽  
Aijun Liu ◽  
Fenghua Wang ◽  
Robert W Allan ◽  
Kaiyong Mei ◽  
...  
Keyword(s):  
Germ Cell ◽  
Rna Binding ◽  
Immunohistochemical Study ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Germ Cell Tumors ◽  
Extragonadal Germ Cell Tumors

RNA-binding protein LIN28 is a marker for testicular germ cell tumors

2011 ◽  
Vol 42 (5) ◽  
pp. 710-718 ◽  
Author(s):  
Dengfeng Cao ◽  
Robert W. Allan ◽  
Liang Cheng ◽  
Yan Peng ◽  
Charles C. Guo ◽  
...  
Keyword(s):  
Germ Cell ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Germ Cell Tumors ◽  
Testicular Germ Cell Tumors ◽  
Testicular Germ Cell

RNA-binding protein LIN28 is a sensitive marker of ovarian primitive germ cell tumours

2011 ◽  
Vol 59 (3) ◽  
pp. 452-459 ◽  
Author(s):  
Debin Xue ◽  
Yan Peng ◽  
Fenghua Wang ◽  
Robert W Allan ◽  
Dengfeng Cao
Keyword(s):  
Germ Cell ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Germ Cell Tumours ◽  
Sensitive Marker

scholarly journals Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse

2008 ◽  
Vol 17 (18) ◽  
pp. 2803-2818 ◽  
Author(s):  
Ingrid Ehrmann ◽  
Caroline Dalgliesh ◽  
Aikaterini Tsaousi ◽  
Maria Paola Paronetto ◽  
Bettina Heinrich ◽  
...  
Keyword(s):  
Germ Cell ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Nuclear Rna

scholarly journals Male Germ Cell-Specific RNA Binding Protein RBMY: A New Oncogene Explaining Male Predominance in Liver Cancer

PLoS ONE ◽  
2011 ◽  
Vol 6 (11) ◽  
pp. e26948 ◽  
Author(s):  
Daw-Jen Tsuei ◽  
Po-Huang Lee ◽  
Hsiao-Yu Peng ◽  
Shau-Lin Lu ◽  
De-Shiuan Su ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Germ Cell ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Male Germ Cell ◽  
Male Predominance

scholarly journals Author response: An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning

2018 ◽  
Author(s):  
Ingrid Ehrmann ◽  
James H Crichton ◽  
Matthew R Gazzara ◽  
Katherine James ◽  
Yilei Liu ◽  
...  
Keyword(s):  
Germ Cell ◽  
Splice Site ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Author Response ◽  
Cryptic Splice Site

RNA binding protein Musashi‐1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus

2015 ◽  
Vol 29 (7) ◽  
pp. 2759-2768 ◽  
Author(s):  
Jessie M. Sutherland ◽  
Alexander P. Sobinoff ◽  
Barbara A. Fraser ◽  
Kate A. Redgrove ◽  
Tara‐Lynne Davidson ◽  
...  
Keyword(s):  
Germ Cell ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Cell Development ◽  
Germ Cell Development

scholarly journals The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming

Development ◽  
2019 ◽  
Vol 146 (19) ◽  
pp. dev175950 ◽  
Author(s):  
Victor A. Ruthig ◽  
Matthew B. Friedersdorf ◽  
Jason A. Garness ◽  
Steve C. Munger ◽  
Corey Bunce ◽  
...  
Keyword(s):  
Germ Cell ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Negative Regulator ◽  
Cell Reprogramming ◽  
Positive Regulator ◽  
Epigenetic Modifiers

scholarly journals A testis cytoplasmic RNA-binding protein that has the properties of a translational repressor.

1996 ◽  
Vol 16 (6) ◽  
pp. 3023-3034 ◽  
Author(s):  
K Lee ◽  
M A Fajardo ◽  
R E Braun
Keyword(s):  
Germ Cell ◽  
Untranslated Region ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Male Germ Cell ◽  
Translational Repression ◽  
Translational Repressor ◽  
Germ Cell Differentiation

Translation of the mouse protamine 1 (Prm-1) mRNA is repressed for several days during male germ cell differentiation. With the hope of cloning genes that regulate the translational repression of Prm-1, we screened male germ cell cDNA expression libraries with the 3' untranslated region of the Prm-1 RNA. From this screen we obtained two independent clones that encode Prbp, a Prm-1 RNA-binding protein. Prbp contains two copies of a double-stranded-RNA-binding domain. In vitro, the protein binds to a portion of the Prm-1 3' untranslated region previously shown to be sufficient for translational repression in transgenic mice, as well as to poly(I). poly(C). Prbp protein is present in multiple forms in cytoplasmic extracts prepared from wild-type mouse testes and is absent from testes of germ cell-deficient mouse mutants, suggesting that Prbp is restricted to the germ cells of the testis. Immunocytochemical localization confirmed that Prbp is present in the cytoplasmic compartment of late-stage meiotic cells and haploid round spermatids. Recombinant Prbp protein inhibits the translation of multiple mRNAs in a wheat germ lysate, suggesting that Prbp acts to repress translation in round spermatids. While this protein lacks complete specificity for Prm-1-containing RNAs in vitro, the properties of Prbp are consistent with it acting as a general repressor of translation.

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