scholarly journals Peripheral natural killer cell and allo-stimulated T-cell function in kidney transplant recipients associate with cancer risk and immunosuppression-related complications

2015 ◽  
Vol 88 (6) ◽  
pp. 1374-1382 ◽  
Author(s):  
Christopher M. Hope ◽  
Alexander Troelnikov ◽  
William Hanf ◽  
Shilpanjali Jesudason ◽  
Patrick T. Coates ◽  
...  
2018 ◽  
Vol 19 (1) ◽  
pp. 166-177 ◽  
Author(s):  
Claire Dendle ◽  
Poh‐Yi Gan ◽  
Kevan R. Polkinghorne ◽  
James Ngui ◽  
Rhonda L. Stuart ◽  
...  

2010 ◽  
Vol 135 ◽  
pp. S59-S60
Author(s):  
Martin Gasser ◽  
Igor Tsaur ◽  
Kai Lopau ◽  
Christoph Germer ◽  
Anil Chandraker ◽  
...  

2011 ◽  
Vol 79 (9) ◽  
pp. 1005-1012 ◽  
Author(s):  
Igor Tsaur ◽  
Martin Gasser ◽  
Beatriz Aviles ◽  
Jens Lutz ◽  
Lydia Lutz ◽  
...  

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Cody Orr ◽  
Henry Masur ◽  
Shyam Kottilil ◽  
Eric G Meissner

Abstract To identify immunologic correlates of hepatitis C virus (HCV) relapse after direct-acting antiviral (DAA) therapy, we quantified select immune transcripts in whole blood from noncirrhotic HCV subjects treated with 4–6 weeks of DAAs. We identified specific markers of natural killer-cell and CD8+ T-cell function (GZMB, PRF1, NKp46) with higher expression in subjects who relapsed. These findings suggest a role for host immunity in HCV eradication with ultrashort DAA therapy. We quantified whole blood immune transcripts in noncirrhotic HCV subjects treated with shortcourse antiviral therapy. Markers of natural killer-cell and CD8+ T-cell function had higher expression in virologic relapsers, suggesting a role for host immunity in HCV eradication.


2017 ◽  
Vol 31 (2) ◽  
pp. 187-197 ◽  
Author(s):  
Mario Fernández-Ruiz ◽  
Julia Origüen ◽  
David Lora ◽  
Francisco López-Medrano ◽  
Esther González ◽  
...  

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