scholarly journals The Case | Renal dysfunction in a pregnant patient with IgA nephropathy

2014 ◽  
Vol 85 (6) ◽  
pp. 1477-1478 ◽  
Author(s):  
Ladan Zand ◽  
Amy Williams ◽  
Dusica Babovic-Vuksanovic ◽  
Rosemary Nwoko ◽  
Lynn Cornell ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Pregnant Patient

The effectiveness of steroid therapy for advanced IgA nephropathy with renal dysfunction

Nephrology ◽  
2002 ◽  
Vol 7 ◽  
pp. A111-A112
Author(s):  
T MORIYAMA ◽  
K HONDA ◽  
Y WATANABE ◽  
M ITABASHI ◽  
M TSUKADA ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Steroid Therapy

scholarly journals Role of myofibroblasts and collagen type IV in patients of IgA nephropathy as markers of renal dysfunction

2010 ◽  
Vol 20 (1) ◽  
pp. 34 ◽  
Author(s):  
RW Minz ◽  
A Bakshi ◽  
S Chhabra ◽  
K Joshi ◽  
V Sakhuja
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Collagen Type ◽  
Collagen Type Iv ◽  
Type Iv

MO296MEAN PLATELET VOLUME IN FAMILIAL MEDITERRANEAN FEVER RELATED AMYLOIDOSIS AND COMPARISON WITH COMMON PRIMARY GLOMERULAR DISEASES

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Tolga Yildirim ◽  
Berranur Kutahya ◽  
Fatma Is ◽  
Mehmet Erdevir ◽  
Muge Uzerk Kibar ◽  
...  
Keyword(s):  
Familial Mediterranean Fever ◽  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Membranous Glomerulonephritis ◽  
The Other ◽  
Healthy Controls ◽  
Platelet Volume ◽  
Glomerular Diseases ◽  
Factors Affecting ◽  
Mediterranean Fever

Abstract Background and Aims Compared to healthy controls, mean platelet volume (MPV) is frequently higher in patients with Familial Mediterranean fever (FMF) but lower in amyloidosis patients. The cause of differing MPV levels in FMF patients with and without amyloidosis is not clear. We hypothesized that severe proteinuria and renal dysfunction in amyloidosis could be responsible from low MPV in contrast to FMF patients without amyloidosis. We aimed to compare MPV levels of FMF patients with amyloidosis and MPV values of patients with different glomerular diseases to understand if low MPV is unique to amyloidosis or MPV is similar in all glomerular diseases indicating that it is a consequence of proteinuria and/or renal dysfunction. Method We compared pre-biopsy MPV levels of patients with amyloidosis secondary to FMF, to MPV levels of patients with membranous glomerulonephritis, focal segmental glomerulosclerosis (FSGS) and IgA nephropathy that all present with proteinuria and renal dysfunction. Factors affecting MPV were also determined. Results 703 patients (411 male, 292 female) were included in the study. Mean age was 42.6±14.3 years. There were 124 patients with amyloidosis, 224 patients with IgA nephropathy, 188 patients with membranous glomerulonephritis and 167 patients with FSGS. Patients with amyloidosis had lower MPV compared to patients without amyloidosis (7.9±1.2 fL vs. 8.2±0.9 fL respectively, p=0.008). Patients with amyloidosis had also significantly lower MPV compared to patients with each of the other diagnoses. MPV was negatively correlated with platelet count (r = - 0.351, p <0.001). There was no significant correlation of MPV with serum creatinine and proteinuria. Conclusion This study is the largest study of MPV in patients with biopsy proven amyloidosis and confirms previous studies reporting low MPV in amyloidosis. This study indicates that low MPV in amyloidosis cannot be explained with severe proteinuria and renal dysfunction.

The effectiveness of steroid therapy for advanced IgA nephropathy with renal dysfunction

Nephrology ◽  
2008 ◽  
Vol 7 ◽  
pp. A111-A111
Author(s):  
T MORIYAMA ◽  
K HONDA ◽  
Y WATANABE ◽  
M ITABASHI ◽  
M TSUKADA ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Steroid Therapy

scholarly journals Association between VDR gene FokI polymorphism and renal function in patients with IgA nephropathy

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7092
Author(s):  
Man-Qiu Mo ◽  
Ling Pan ◽  
Lin Tan ◽  
Ling Jiang ◽  
Yong-Qing Pan ◽  
...  
Keyword(s):  
Renal Function ◽  
Regression Analysis ◽  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Interstitial Fibrosis ◽  
Direct Sequencing ◽  
Linear Regression Analysis ◽  
Control Group ◽  
Increased Risk ◽  
The Relationship

Background Studies have shown that the occurrence and development of IgA nephropathy (IgAN) are genetically susceptible, but the relationship between vitamin D receptor (VDR) gene polymorphisms and renal function in IgAN patients is unclear. Methods We investigated the relationship between VDR FokI (rs2228570) single nucleotide polymorphism (SNP) and renal function and related clinicopathologic parameters in IgAN patients. Clinical and pathological data of 282 IgAN patients treated at the First Affiliated Hospital of Guangxi Medical University were collected, and FokI genotypes were determined by PCR and direct sequencing. Patients were divided into the renal dysfunction group and normal renal function (control) group by estimated glomerular filtration rate (eGFR) and serum creatinine level. Results Frequencies of TT genotype and T allele in the renal dysfunction group were higher than those of the control group. Blood urea nitrogen, serum phosphorus (P), proportions of mesangial cell proliferation, interstitial fibrosis/tubular atrophy and crescents in T allele carriers were higher than those in non-T allele carriers, while eGFR and 25-Hydroxyvitamin D3 were lower in T allele carriers than non-T allele carriers. Multiple linear regression analysis showed that eGFR was affected by FokI genotypes in IgAN patients. Logistics regression analysis showed that middle and elderly age, elevated P, intact parathyroid hormone and TT genotype were independent risk factors for renal dysfunction in IgAN patients; the odds ratio of carrying the TT genotype was as high as 84.77 (P < 0.05 for all). Conclusions IgA nephropathy patients carrying the VDR FokI TT genotype have an increased risk of renal dysfunction. VDR FokI SNP is closely related to renal function, calcium-phosphate metabolism, and related pathological damage in IgAN patients.

scholarly journals A Randomized, Controlled Trial of Rituximab in IgA Nephropathy with Proteinuria and Renal Dysfunction

2016 ◽  
Vol 28 (4) ◽  
pp. 1306-1313 ◽  
Author(s):  
Richard A. Lafayette ◽  
Pietro A. Canetta ◽  
Brad H. Rovin ◽  
Gerald B. Appel ◽  
Jan Novak ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Controlled Trial ◽  
Randomized Controlled

scholarly journals Differential expression of glycogenes in tonsillar B lymphocytes in association with proteinuria and renal dysfunction in IgA nephropathy

2010 ◽  
Vol 136 (3) ◽  
pp. 447-455 ◽  
Author(s):  
Tatsuyuki Inoue ◽  
Hitoshi Sugiyama ◽  
Yoshiyuki Hiki ◽  
Keiichi Takiue ◽  
Hiroshi Morinaga ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Differential Expression ◽  
B Lymphocytes

Interstitial inflammation and the expression of apoptotic modulators in iga nephropathy

Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A114-A114
Author(s):  
Menahem Sa ◽  
Maguire Ja ◽  
Stein‐Oakley A ◽  
Bailey M ◽  
Dowling J ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Interstitial Inflammation

The Management of the Isosensitized Pregnant Patient and Her Erythroblastotic Infant

1951 ◽  
Vol 35 (3) ◽  
pp. 749-770 ◽  
Author(s):  
Alexander S. Wiener ◽  
Irving B. Wexler ◽  
Theodore H. Grundfast
Keyword(s):  
Pregnant Patient
Sign in / Sign up

Export Citation Format

Share Document