scholarly journals Macroscopic hematuria in mesangial IgA nephropathy: Correlation with glomerular crescents and renal dysfunction

1983 ◽  
Vol 23 (2) ◽  
pp. 393-400 ◽  
Author(s):  
William M. Bennett ◽  
Priscilla Kincaid-Smith
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Macroscopic Hematuria

The effectiveness of steroid therapy for advanced IgA nephropathy with renal dysfunction

Nephrology ◽  
2002 ◽  
Vol 7 ◽  
pp. A111-A112
Author(s):  
T MORIYAMA ◽  
K HONDA ◽  
Y WATANABE ◽  
M ITABASHI ◽  
M TSUKADA ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Steroid Therapy

IgA Nephropathy: Association of a History of Macroscopic Hematuria Episodes with Increased Production of Polymeric IgA

Nephron ◽  
1987 ◽  
Vol 45 (2) ◽  
pp. 98-103 ◽  
Author(s):  
Luz Lozano ◽  
Rosa García-Hoyo ◽  
Jesús Egido
Keyword(s):  
Iga Nephropathy ◽  
Macroscopic Hematuria ◽  
History Of

scholarly journals Tonsillectomy in IgA Nephropathy - Clinical Case

2021 ◽  
Vol 26 (3) ◽  
pp. 59-61
Author(s):  
Livia Mirela Popa ◽  
Livia Popa ◽  
Cătălin-Bogdan Osalciuc
Keyword(s):  
Antibiotic Therapy ◽  
Iga Nephropathy ◽  
Clinical Case ◽  
Acute Infection ◽  
Acute Onset ◽  
First Episode ◽  
Urinary Volume ◽  
Upper Airways ◽  
Macroscopic Hematuria ◽  
Nephritic Syndrome

Abstract This article presents the clinical case of IgA nephropathy of a patient hospitalized in order to investigate a nephritic syndrome, apparently with acute onset, discovered in the following circumstances: recurrent macroscopic hematuria, decreased urinary volume, the first episode occurring about a month ago in the context of an acute infection of upper airways, remitted under antibiotic therapy, with reappearance every 2 weeks, also accompanied by odynophagia and decreased urinary volume.

scholarly journals Indian scenario of IgA nephropathy: a systematic review and meta-analysis

2021 ◽  
Vol 21 (1) ◽  
pp. 159-65
Author(s):  
Anju Khairwa
Keyword(s):  
Systematic Review ◽  
Iga Nephropathy ◽  
Clinical Features ◽  
Meta Analysis ◽  
Microscopic Hematuria ◽  
Macroscopic Hematuria ◽  
Female Ratio ◽  
Cochrane Database ◽  
Male Female Ratio ◽  
Indian Scenario

Background: IgA nephropathy (IgAN) is most common primary glomerulopathy. There are variations in prevalence of IgAN and its clinical features in different studies from India. Aim: To summarize overall scenario of IgAN in India. Methods: In this systematic review, studies related to IgAN and related renal disease were included. Data searched were PubMed, EMBASE, Google scholar, and Cochrane Database from inception to 31st January 2019. Results: Total 49 studies (N=2480) were included: 21studies (N=2309) of primary IgAN; 19 studies (N=21) of Secondary IgAN; four studies (N=133) of IgA vasculitis nephropathy (IgAVN); and five studies (N=17) of IgA dominant nephropathy (IgADN). Prevalence of IgAN was 16.5% in India. Age of affected persons was ranging from 27.2±16.7 to 48.6±21.3 years . Male female ratio was 1.8:1. Clinical features of Primary IgAN, IgAVN, IgADN & Secondary IgAN were microscopic hematuria (49.6%, 44.4%, 15.6% & 59.5%), macroscopic hematuria (5.1%, 0.4%,40.9%,& 35.7%), Subnephrotic proteinuria (42.1%, 29.4%, 23.2%, & 52.3%), nephrotic proteinuria (16.0%, 4.4%, 76.8%,& 47.6%), and hypertension (25.8%,18.3%, 35.5%,& 47.6%).. The 24 hours proteinuria was ranging from 2.6±1.5 to 4.7±2.3 gm/day and serum creatinine (mg/dl) was ranging from 0.9±0 to 3.5±3.9 mg/dl. Histolomorphologically, all type of IgAN showed mesangial hypercellularity and Immunofluorescence revealed IgA deposition. Conclusion: The overall prevalence of primary IgAN in India was 16.5%. The subnephrotic proteinuria and microscopic hematuria were common clinical features. Keywords: IgA Nephropathy; histomorphology; prevalence; India.

scholarly journals The Case | Renal dysfunction in a pregnant patient with IgA nephropathy

2014 ◽  
Vol 85 (6) ◽  
pp. 1477-1478 ◽  
Author(s):  
Ladan Zand ◽  
Amy Williams ◽  
Dusica Babovic-Vuksanovic ◽  
Rosemary Nwoko ◽  
Lynn Cornell ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Pregnant Patient

scholarly journals Role of myofibroblasts and collagen type IV in patients of IgA nephropathy as markers of renal dysfunction

2010 ◽  
Vol 20 (1) ◽  
pp. 34 ◽  
Author(s):  
RW Minz ◽  
A Bakshi ◽  
S Chhabra ◽  
K Joshi ◽  
V Sakhuja
Keyword(s):  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Collagen Type ◽  
Collagen Type Iv ◽  
Type Iv

scholarly journals A Case of Arteriovenous Fistula after Renal Biopsy in an IgA Nephropathy Patient with Macroscopic Hematuria

2013 ◽  
Vol 3 (1) ◽  
pp. 64-68 ◽  
Author(s):  
Satoshi Horikoshi ◽  
Akiko Takahata ◽  
Akihiko Shiraishi ◽  
Hiromitsu Fukuda ◽  
Isao Ohsawa ◽  
...  
Keyword(s):  
Renal Biopsy ◽  
Arteriovenous Fistula ◽  
Iga Nephropathy ◽  
Macroscopic Hematuria

scholarly journals P0488IG A NEPHROPATHY: ANALYSIS OF 501 BIOPSY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Marwa Omrane ◽  
Raja Aoudia ◽  
Mondher Ounissi ◽  
Soumaya Chargui ◽  
Mouna Jerbi ◽  
...  
Keyword(s):  
Renal Biopsy ◽  
Iga Nephropathy ◽  
Vascular Lesions ◽  
Macroscopic Hematuria ◽  
Systematic Screening ◽  
Female Ratio ◽  
Male Predominance ◽  
Glomerular Lesions ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background and Aims Mesangial deposits Ig A was described the first time in 1968 by Berger and Hinglais. It remains the most common primary glomerulonephritis worldwide. It is often idiopathic but can also be secondary. The aim of our study is to describe the epidemiologic characteristics, the incidence and the anatomopathological features of 501 IgA nephropathy (IgA N) patients. Method It is a retrospective mono-centric study including patients having IgA N in the renal biopsy done in our department among a period of 17 years. Results We analyzed data of 8427 patients who underwent renal biopsy. 81% had glomerular nephropathy with 7.3% (501) IgA N. A male-to-female ratio of 2.27. The average age was 28.7 years. IgA N was primary in 80.2% cases and secondary in 17.8% cases. The most frequent secondary IgA N was rheumatoid purpura (74.8%). There was a male predominance in Berger‘s disease as well as in rheumatoid purpura. Berger’s disease was more common in adults, whereas rheumatoid purpura was more common in children. The main indication of renal biopsy was proteinuria with hematuria in 23.2% of cases and nephrotic syndrome in 23.8%. The association of non-nephrotic proteinuria, hematuria, arterial hypertension and renal injury was found in 9.3% whereas isolated macroscopic hematuria only in 6.4% of cases. According to HAAS classification, HAAS 3 was the most frequent. OXFORD classification used only from 2010, and M1, S1, E0, T0 and M1, S1, E0, T2 were the most frequent. Glomerular lesions were associated to tubulo interstitial and vascular lesions in 48.2% of cases. Conclusion IgA nephropathy is the most common glomerular disease and a frequent cause of end stage renal disease. Because of a clear increase of it’s incidence in our country and the delay in the diagnosis, a systematic screening of urines is needed in our country as it’s done in Singapore and Japan.

MO296MEAN PLATELET VOLUME IN FAMILIAL MEDITERRANEAN FEVER RELATED AMYLOIDOSIS AND COMPARISON WITH COMMON PRIMARY GLOMERULAR DISEASES

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Tolga Yildirim ◽  
Berranur Kutahya ◽  
Fatma Is ◽  
Mehmet Erdevir ◽  
Muge Uzerk Kibar ◽  
...  
Keyword(s):  
Familial Mediterranean Fever ◽  
Renal Dysfunction ◽  
Iga Nephropathy ◽  
Membranous Glomerulonephritis ◽  
The Other ◽  
Healthy Controls ◽  
Platelet Volume ◽  
Glomerular Diseases ◽  
Factors Affecting ◽  
Mediterranean Fever

Abstract Background and Aims Compared to healthy controls, mean platelet volume (MPV) is frequently higher in patients with Familial Mediterranean fever (FMF) but lower in amyloidosis patients. The cause of differing MPV levels in FMF patients with and without amyloidosis is not clear. We hypothesized that severe proteinuria and renal dysfunction in amyloidosis could be responsible from low MPV in contrast to FMF patients without amyloidosis. We aimed to compare MPV levels of FMF patients with amyloidosis and MPV values of patients with different glomerular diseases to understand if low MPV is unique to amyloidosis or MPV is similar in all glomerular diseases indicating that it is a consequence of proteinuria and/or renal dysfunction. Method We compared pre-biopsy MPV levels of patients with amyloidosis secondary to FMF, to MPV levels of patients with membranous glomerulonephritis, focal segmental glomerulosclerosis (FSGS) and IgA nephropathy that all present with proteinuria and renal dysfunction. Factors affecting MPV were also determined. Results 703 patients (411 male, 292 female) were included in the study. Mean age was 42.6±14.3 years. There were 124 patients with amyloidosis, 224 patients with IgA nephropathy, 188 patients with membranous glomerulonephritis and 167 patients with FSGS. Patients with amyloidosis had lower MPV compared to patients without amyloidosis (7.9±1.2 fL vs. 8.2±0.9 fL respectively, p=0.008). Patients with amyloidosis had also significantly lower MPV compared to patients with each of the other diagnoses. MPV was negatively correlated with platelet count (r = - 0.351, p <0.001). There was no significant correlation of MPV with serum creatinine and proteinuria. Conclusion This study is the largest study of MPV in patients with biopsy proven amyloidosis and confirms previous studies reporting low MPV in amyloidosis. This study indicates that low MPV in amyloidosis cannot be explained with severe proteinuria and renal dysfunction.

scholarly journals Acute worsening of renal function during episodes of macroscopic hematuria in IgA nephropathy

1985 ◽  
Vol 28 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Manuel Praga ◽  
Victor Gutierrez-Millet ◽  
José J. Navas ◽  
Luis M. Ruilope ◽  
José M. Morales ◽  
...  
Keyword(s):  
Renal Function ◽  
Iga Nephropathy ◽  
Macroscopic Hematuria
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