scholarly journals Inhibitory effect of calcium channel blockers on human mesangial cell growth: Evidence for actions independent of L-type Ca2+ channels

1996 ◽  
Vol 49 (3) ◽  
pp. 868-879 ◽  
Author(s):  
Stephan R. Orth ◽  
Rainer Nobiling ◽  
Sabine Bönisch ◽  
Eberhard Ritz
Keyword(s):  
Cell Growth ◽  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Mesangial Cell ◽  
Inhibitory Effect ◽  
Channel Blockers ◽  
Human Mesangial Cell ◽  
Ca2 Channels

Inhibitory Effect of Calcium Channel Blockers on Growth of Pancreatic Cancer Cells

Pancreas ◽  
1994 ◽  
Vol 9 (2) ◽  
pp. 193-202 ◽  
Author(s):  
Kazuo Sato ◽  
Jin Ishizuka ◽  
Cary W. Cooper ◽  
Dai H. Chung ◽  
Takashi Tsuchiya ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Calcium Channel ◽  
Cancer Cells ◽  
Calcium Channel Blockers ◽  
Inhibitory Effect ◽  
Channel Blockers ◽  
Pancreatic Cancer Cells

scholarly journals Regulation of cultured human mesangial cell growth by ionized macromolecules.

1992 ◽  
Vol 2 (10) ◽  
pp. S95
Author(s):  
F Pugliese ◽  
G A Cinotti ◽  
P Menè
Keyword(s):  
Cell Growth ◽  
Mesangial Cell ◽  
Mesangial Cells ◽  
Fetal Bovine Serum ◽  
Inhibitory Effect ◽  
The Other ◽  
Net Charge ◽  
Human Mesangial Cells ◽  
Human Mesangial Cell ◽  
Fetal Bovine

We evaluated the importance of the net charge of polyionic macromolecules in the regulation of cultured human mesangial cell growth. Structurally unrelated polyanionic compounds, i.e., heparin, suramin, poly-L-aspartic acid, and poly-L-glutamic acid, strongly inhibited 10% fetal bovine serum-stimulated cell proliferation. On the other hand, two polycations, protamin sulfate and poly-L-lysine, were equally effective in inhibiting cell growth. The antiproliferative activity of each compound was neutralized by molecules with opposite net charge. These data indicate that both anionic and cationic macromolecules exert an antimitogenic effect on cultured human mesangial cells. This inhibitory effect is dependent upon charge density rather than on the net electric charge of each compound.

scholarly journals CYP3A4 Genetic Status May Be Associated With Increased Vulnerability to the Inhibitory Effect of Calcium-Channel Blockers on Clopidogrel

2013 ◽  
Vol 77 (5) ◽  
pp. 1289-1296 ◽  
Author(s):  
Jin Joo Park ◽  
Kyung Woo Park ◽  
Jeehoon Kang ◽  
Ki-Hyun Jeon ◽  
Si-Hyuck Kang ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Inhibitory Effect ◽  
Channel Blockers ◽  
Genetic Status

Inhibitory effect of calcium channel blockers on proliferation of human glioma cellsin vitro

1989 ◽  
Vol 79 (2) ◽  
pp. 166-169 ◽  
Author(s):  
J. Kunert-Radek ◽  
H. Stepien ◽  
A. Radek ◽  
K. Lyson ◽  
M. Pawlikowski
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Inhibitory Effect ◽  
Channel Blockers ◽  
Human Glioma
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