scholarly journals The utilization of circulating cell-free fetal DNA testing and decrease in invasive diagnostic procedures: an institutional experience

2014 ◽  
Vol 34 (10) ◽  
pp. 750-753 ◽  
Author(s):  
K E Pettit ◽  
A D Hull ◽  
L Korty ◽  
M C Jones ◽  
D H Pretorius
Keyword(s):  
Diagnostic Procedures ◽  
Dna Testing ◽  
Fetal Dna ◽  
Cell Free Fetal Dna ◽  
Institutional Experience

scholarly journals Non Invasive Prenatal Diagnosis of Aneuploidy: Next Generation Sequencing or Fetal DNA Enrichment?

2012 ◽  
Vol 15 (Supplement) ◽  
pp. 17-26 ◽  
Author(s):  
Neil D. Avent ◽  
A Webb ◽  
TE Madgett ◽  
T Miran ◽  
K Sillence ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Detection Rate ◽  
Improve Patient Safety ◽  
Chorionic Villus ◽  
Diagnostic Procedures ◽  
Chorionic Villus Sampling ◽  
Group Status ◽  
Non Invasive ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

ABSTRACT Current invasive procedures [amniocentesis and chorionic villus sampling (CVS)] pose a risk to mother and fetus and such diagnostic procedures are available only to high risk pregnancies limiting aneuploidy detection rate. This review seeks to highlight the necessity of investing in non invasive prenatal diagnosis (NIPD) and how NIPD would improve patient safety and detection rate as well as allowing detection earlier in pregnancy. Non invasive prenatal diagnosis can take either a proteomics approach or nucleic acid-based approach; this review focuses on the latter. Since the discovery of cell free fetal DNA (cffDNA) and fetal RNA in maternal plasma, procedures have been developed for detection for monogenic traits and for some have become well established (e.g., RHD blood group status). However, NIPD of aneuploidies remains technically challenging. This review examines currently published literature evaluating techniques and approaches that have been suggested and developed for aneuploidy detection, highlighting their advantages and limitations and areas for further research.

scholarly journals Cell-free fetal DNA testing in singleton IVF conceptions

2018 ◽  
Vol 33 (4) ◽  
pp. 572-578 ◽  
Author(s):  
Timothy J Lee ◽  
Daniel L Rolnik ◽  
Melody A Menezes ◽  
Andrew C McLennan ◽  
Fabricio da Silva Costa
Keyword(s):  
Dna Testing ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

scholarly journals Cell-free fetal DNA testing: a pilot study of obstetric healthcare provider attitudes toward clinical implementation

2011 ◽  
Vol 31 (11) ◽  
pp. 1070-1076 ◽  
Author(s):  
Lauren C. Sayres ◽  
Megan Allyse ◽  
Mary E. Norton ◽  
Mildred K. Cho
Keyword(s):  
Pilot Study ◽  
Healthcare Provider ◽  
Dna Testing ◽  
Clinical Implementation ◽  
Provider Attitudes ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

scholarly journals Cell-free fetal DNA testing: who is driving implementation?

2012 ◽  
Vol 15 (6) ◽  
pp. 433-434 ◽  
Author(s):  
Jessica Mozersky ◽  
Michael T. Mennuti
Keyword(s):  
Dna Testing ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

Detection of Y chromosome material in a 46,XX male with SRY translocation: novel application of cell-free fetal DNA testing

2015 ◽  
Vol 35 (8) ◽  
pp. 823-825 ◽  
Author(s):  
Kalina Benedict ◽  
Christina S. Han ◽  
Neil S. Silverman ◽  
Deborah Krakow ◽  
Lawrence D. Platt
Keyword(s):  
Y Chromosome ◽  
Dna Testing ◽  
Fetal Dna ◽  
Cell Free Fetal Dna ◽  
Chromosome Material ◽  
Xx Male
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