Detection of Y chromosome material in a 46,XX male with SRY translocation: novel application of cell-free fetal DNA testing

2015 ◽  
Vol 35 (8) ◽  
pp. 823-825 ◽  
Author(s):  
Kalina Benedict ◽  
Christina S. Han ◽  
Neil S. Silverman ◽  
Deborah Krakow ◽  
Lawrence D. Platt
Keyword(s):  
Y Chromosome ◽  
Dna Testing ◽  
Fetal Dna ◽  
Cell Free Fetal Dna ◽  
Chromosome Material ◽  
Xx Male

Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance

2016 ◽  
Vol 36 (4) ◽  
pp. 353-361 ◽  
Author(s):  
Giulia Breveglieri ◽  
Elisabetta Bassi ◽  
Silvia Carlassara ◽  
Lucia Carmela Cosenza ◽  
Patrizia Pellegatti ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Y Chromosome ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Chromosome Identification ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

scholarly journals Cell-free fetal DNA testing in singleton IVF conceptions

2018 ◽  
Vol 33 (4) ◽  
pp. 572-578 ◽  
Author(s):  
Timothy J Lee ◽  
Daniel L Rolnik ◽  
Melody A Menezes ◽  
Andrew C McLennan ◽  
Fabricio da Silva Costa
Keyword(s):  
Dna Testing ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

scholarly journals Cell-free fetal DNA testing: a pilot study of obstetric healthcare provider attitudes toward clinical implementation

2011 ◽  
Vol 31 (11) ◽  
pp. 1070-1076 ◽  
Author(s):  
Lauren C. Sayres ◽  
Megan Allyse ◽  
Mary E. Norton ◽  
Mildred K. Cho
Keyword(s):  
Pilot Study ◽  
Healthcare Provider ◽  
Dna Testing ◽  
Clinical Implementation ◽  
Provider Attitudes ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

scholarly journals Detection of SRY‐positive46,XX male syndrome by the analysis of cell‐free fetal DNA via non‐invasive prenatal testing

2019 ◽  
Vol 7 (10) ◽  
pp. 1977-1981
Author(s):  
Luigia De Falco ◽  
Giovanni Savarese ◽  
Teresa Suero ◽  
Sonia Amabile ◽  
Raffaella Ruggiero ◽  
...  
Keyword(s):  
Prenatal Testing ◽  
Non Invasive ◽  
Fetal Dna ◽  
Cell Free Fetal Dna ◽  
Xx Male

Application of real-time PCR of sex-independent insertion-deletion polymorphisms to determine fetal sex using cell-free fetal DNA from maternal plasma

2015 ◽  
Vol 53 (8) ◽  
Author(s):  
Sherry Sze Yee Ho ◽  
Angela Barrett ◽  
Henna Thadani ◽  
Cecille Laureano Asibal ◽  
Evelyn Siew-Chuan Koay ◽  
...  
Keyword(s):  
Real Time ◽  
Y Chromosome ◽  
Real Time Pcr ◽  
Genetic Material ◽  
Maternal Plasma ◽  
Fetal Sex ◽  
Female Fetus ◽  
Non Invasive ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

AbstractPrenatal diagnosis of sex-linked disorders requires invasive procedures, carrying a risk of miscarriage of up to 1%. Cell-free fetal DNA (cffDNA) present in cell-free DNA (cfDNA) from maternal plasma offers a non-invasive source of fetal genetic material for analysis. Detection of Y-chromosome sequences in cfDNA indicates presence of a male fetus; in the absence of a Y-chromosome signal a female fetus is inferred. We aimed to validate the clinical utility of insertion-deletion polymorphisms (INDELs) to confirm presence of a female fetus using cffDNA.Quantitative real-time PCR (qPCR) for the Y-chromosome-specific sequence,Fetal sex was correctly determined in 77/82 (93.9%) cfDNA samples.We have validated a non-invasive prenatal test to confirm fetal sex as early as 6 gestational weeks using cffDNA from maternal plasma.

scholarly journals Cell-free fetal DNA testing: who is driving implementation?

2012 ◽  
Vol 15 (6) ◽  
pp. 433-434 ◽  
Author(s):  
Jessica Mozersky ◽  
Michael T. Mennuti
Keyword(s):  
Dna Testing ◽  
Fetal Dna ◽  
Cell Free Fetal Dna
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