scholarly journals Clinician Scientists and PhDs: The Need to Connect Basic Research to Translational Medicine—A Personal Experience

2014 ◽  
Vol 134 (2) ◽  
pp. 295-298 ◽  
Author(s):  
Carien M. Niessen ◽  
Thomas Krieg
Keyword(s):  
Translational Medicine ◽  
Personal Experience ◽  
Basic Research

scholarly journals Value-Oriented Consciousness

2015 ◽  
pp. 244-250
Author(s):  
V. V. Matyushina
Keyword(s):  
Personal Experience ◽  
Real Life ◽  
Basic Research ◽  
Special Focus ◽  
Special Device ◽  
Specific System ◽  
Word Meanings ◽  
World Outlook ◽  
The World ◽  
Research Pattern

The article regards the interrelation between language and consciousness, but with a special focus on the fact that consciousness is not only the tool and method of reflecting human existence or regulating human actions and relations, but it is as well a special device of evaluating the items and phenomena of real life. Consciousness is understood as a person's world outlook. Society members create and get knowledge in the course of cognitive coactivity. Speech is considered to be one of the types of activity. Outwardly the images of consciousness that are figured in the course of activity are expressed with the help of language tools. The procedure of studying consciousness in psychology is described, in psychology consciousness is understood as a person's image of the world, the connection between consciousness (or the image of the world) and the category of linguistic consciousness is traced, linguistic consciousness is thought to be an integral part of consciousness. As in psychology consciousness is compared with and likened to the so called image of the world, the latter can be represented in a form of the system of meanings. The system of meanings that is moulded in the course of perceiving the real world services and works as a specific system to direct a person in life. The knowledge gained in the course of activity is transformed into personal experience and expertise in a person's consciousness. The essence of the fundamental paradigm of modern psycholinguistics is revealed where the image of linguistic consciousness is the basic research pattern. The image of linguistic consciousness is determined as the image of the world mediated by language, or it can be presented as a collection of images of consciousness expressed with the help of language tools. The images of consciousness exist as word meanings. An attempt is made to prove that linguistic consciousness not only forms, stores or processes language signs and their meanings but also determines the attitude of a person to the items and phenomena of real life. Linguistic consciousness where the axiological factor is regarded as its essence directs a person's activity, determines a person's attitude to the items and phenomena of real life. On the basis of all above - mentioned it is proved that the element of value does exist in linguistic consciousness. Consequently values can be defined as the words with socially built meaning.

scholarly journals CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine

2020 ◽  
Vol 24 (7) ◽  
pp. 3766-3778 ◽  
Author(s):  
Filipe V. Jacinto ◽  
Wolfgang Link ◽  
Bibiana I. Ferreira
Keyword(s):  
Genome Editing ◽  
Translational Medicine ◽  
Basic Research

scholarly journals Swiss institute for translational and entrepreneurial medicine (sitem-insel)

2017 ◽  
Vol 1 (1) ◽  
pp. 2514183X1771410
Author(s):  
Felix J Frey
Keyword(s):  
Private Sector ◽  
Clinical Application ◽  
Translational Medicine ◽  
Continuing Professional Development ◽  
Basic Research ◽  
University Hospital ◽  
Non Profit ◽  
Private Sector Development ◽  
New Findings ◽  
Swiss Institute

sitem-insel – the Swiss Institute for Translational and Entrepreneurial Medicine in Bern – was created to establish, operate and develop a National Center of Excellence for Translational Medicine. sitem-insel is organized as a non-profit oriented public private partnership. Translational medicine is a new, process-oriented discipline that aims to translate new findings and products emerging from private-sector development and basic research into clinical application. The discipline seeks to professionalize the essential interaction between scientists conducting basic research in the private sector and universities, clinicians, regulatory bodies and investors. The mission of sitem-insel is to create and foster an enhanced environment for translational medicine in Switzerland. The sitem-insel strategy rests on three pillars: 1) The sitem-insel School offers university-level continuing professional development courses taught by university and private-sector lecturers. 2) The sitem-insel Enabling Facilities provide infrastructure to foster cooperation between industrial partners, basic scientists and clinicians on the campus of the University Hospital of Bern (Inselspital) with the ultimate goal to bring novel diagnostic and therapeutic products towards clinical application. 3) The sitem-insel Promoting Services aim to optimize the administrative-regulatory effort along the route from laboratory bench to commercial products.

A Metastasis Suppressor Pt-Dendrimer Nanozyme for the Alleviation of Glioblastoma

2021 ◽  
Author(s):  
Jong Min An ◽  
Youngwon Ju ◽  
Jeong Hee Kim ◽  
Hyein Lee ◽  
Yuna Jung ◽  
...  
Keyword(s):  
Translational Medicine ◽  
Basic Research ◽  
Cutting Edge ◽  
Metastasis Suppressor ◽  
Biological Applications ◽  
Enzymatic Characteristics ◽  
Natural Enzyme

Nanozymes are nanostructure-based materials which mimic the enzymatic characteristics of natural enzyme. Biological applications of nanozymes have been highlighted in basic research, industry, and translational medicine as a new cutting-edge...

scholarly journals Embryo-Engineered Nonhuman Primate Models: Progress and Gap to Translational Medicine

Research ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Mei Huang ◽  
Jiao Yang ◽  
Peng Li ◽  
Yongchang Chen
Keyword(s):  
Animal Models ◽  
Nonhuman Primate ◽  
Translational Medicine ◽  
Nonhuman Primates ◽  
Basic Research ◽  
Human Diseases ◽  
Therapeutic Interventions ◽  
Medicine Research ◽  
Close Relatives ◽  
Translational Medicine Research

Animal models of human diseases are vital in better understanding the mechanism of pathogenesis and essential for evaluating and validating potential therapeutic interventions. As close relatives of humans, nonhuman primates (NHPs) play an increasingly indispensable role in advancing translational medicine research. In this review, we summarized the progress of NHP models generated by embryo engineering, analyzed their unique advantages in mimicking clinical patients, and discussed the remaining gap between basic research of NHP models to translational medicine.

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