scholarly journals Possible Pathogenic Role of Th17 Cells for Atopic Dermatitis

2008 ◽  
Vol 128 (11) ◽  
pp. 2625-2630 ◽  
Author(s):  
Chizuko Koga ◽  
Kenji Kabashima ◽  
Noriko Shiraishi ◽  
Miwa Kobayashi ◽  
Yoshiki Tokura
Keyword(s):  
Atopic Dermatitis ◽  
Th17 Cells ◽  
Pathogenic Role

scholarly journals 100 Pathogenic role of interleukin (IL)-26 producing Th17 cells in the acute forms of psoriasis

2018 ◽  
Vol 138 (5) ◽  
pp. S17
Author(s):  
A. Fries ◽  
J. Di Domizio ◽  
O. Demaria ◽  
C. Triboulet ◽  
M. Gilliet
Keyword(s):  
Th17 Cells ◽  
Pathogenic Role

scholarly journals Possible pathogenic role of T helper type 9 cells and interleukin (IL)-9 in atopic dermatitis

2013 ◽  
Vol 175 (1) ◽  
pp. 25-31 ◽  
Author(s):  
L. Ma ◽  
H.-B. Xue ◽  
X.-H. Guan ◽  
C.-M. Shu ◽  
J.-H. Zhang ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
T Helper ◽  
Pathogenic Role ◽  
Helper Type

scholarly journals Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Elisabetta Volpe ◽  
Luca Battistini ◽  
Giovanna Borsellino
Keyword(s):  
Multiple Sclerosis ◽  
Cell Biology ◽  
Th17 Cells ◽  
Bacterial Infections ◽  
Demyelinating Diseases ◽  
T Helper ◽  
Pathogenic Role ◽  
T Helper 17 ◽  
Effector Cytokines

The discovery of the T helper (Th) 17 lineage, involved in the protection against fungal and extracellular bacterial infections, has profoundly revolutionized our current understanding of T cell-mediated responses in autoimmune diseases, including multiple sclerosis (MS). Indeed, recent data demonstrate the pathogenic role of Th17 cells in autoimmune disorders. In particular, studies in MS and in its animal model (EAE, experimental autoimmune encephalomyelitis) have revealed a crucial role of Th17 cells in the pathogenesis of autoimmune demyelinating diseases in both mice and humans. Over the past years, several important aspects concerning Th17 cells have been elucidated, such as the factors which promote or inhibit their differentiation and the effector cytokines which mediate their responses. The identification of the features endowing Th17 cells with high pathogenicity in MS is of particular interest, and discoveries in Th17 cell biology and function could lead to the design of new strategies aimed at modulating the immune response in MS. Here, we will discuss recent advances in this field, with particular focus on the mechanisms conferring pathogenicity in MS and their potential modulation.

Possible role of Th17 cells and IL-17 in the pathogenesis of atopic dermatitis in northern China

2012 ◽  
Vol 68 (1) ◽  
pp. 66-68 ◽  
Author(s):  
Lei Ma ◽  
Hai-Bo Xue ◽  
Xiu-Hao Guan ◽  
Rui-Qun Qi ◽  
Rong-Zhen An ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Th17 Cells ◽  
Northern China
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