scholarly journals Importance of reward and prefrontal circuitry in hunger and satiety: Prader–Willi syndrome vs simple obesity

2011 ◽  
Vol 36 (5) ◽  
pp. 638-647 ◽  
Author(s):  
L M Holsen ◽  
C R Savage ◽  
L E Martin ◽  
A S Bruce ◽  
R J Lepping ◽  
...  
Keyword(s):  
Prader Willi Syndrome ◽  
Simple Obesity ◽  
Prefrontal Circuitry

scholarly journals Comparison of Frequency and Severity of Sleep-Related Breathing Disorders in Children with Simple Obesity and Paediatric Patients with Prader–Willi Syndrome

2021 ◽  
Vol 11 (2) ◽  
pp. 141
Author(s):  
Agnieszka Lecka-Ambroziak ◽  
Marta Wysocka-Mincewicz ◽  
Anna Świercz ◽  
Małgorzata Jędrzejczak ◽  
Mieczysław Szalecki
Keyword(s):  
Insulin Resistance ◽  
Apnea Hypopnea Index ◽  
Oral Glucose ◽  
Prader Willi Syndrome ◽  
Model Assessment ◽  
Sleep Related Breathing Disorders ◽  
Breathing Disorders ◽  
Simple Obesity ◽  
Rhgh Treatment ◽  
Group 1

Sleep-related breathing disorders (SRBDs) can be present in children with simple obesity and with Prader–Willi syndrome (PWS) and influence an individual diagnostic and treatment approach. We compared frequency and severity of SRBDs in children with simple obesity and with PWS, both without and on recombinant human growth hormone (rhGH) treatment, and correlation of SRBDs with insulin resistance tests. A screening polysomnography-polygraphy (PSG), the oral glucose tolerance test (OGTT) and homeostasis model assessment of insulin resistance (HOMA-IR) were analysed in three groups of patients—with simple obesity (group 1, n = 30, mean age 14.2 years), patients with PWS without the rhGH therapy (group 2, n = 8, mean age 13.0 years) and during the rhGH treatment (group 3, n = 17, mean age 8.9 years). The oxygen desaturation index (ODI) was significantly higher in groups 2 and 3, compared to group 1 (p = 0.00), and hypopnea index (HI) was higher in group 1 (p = 0.03). Apnea–hypopnea index (AHI) and apnea index (AI) results positively correlated with the insulin resistance parameters in groups 1 and 3. The PSG values worsened along with the increasing insulin resistance in children with simple obesity and patients with PWS treated with rhGH that may lead to a change in the patients’ care.

scholarly journals Body Composition and Fatness Patterns in Prader-Willi Syndrome: Comparison with Simple Obesity*

Obesity ◽  
2006 ◽  
Vol 14 (10) ◽  
pp. 1685-1690 ◽  
Author(s):  
Mariana F. Theodoro ◽  
Zohreh Talebizadeh ◽  
Merlin G. Butler
Keyword(s):  
Body Composition ◽  
Prader Willi Syndrome ◽  
Simple Obesity

Prader-willi syndrome: Genetics and behavior

1996 ◽  
Vol 71 (4) ◽  
pp. 187-212 ◽  
Author(s):  
Travis Thompson ◽  
Merlin Butler ◽  
William MacLean ◽  
Beth Joseph
Keyword(s):  
Prader Willi Syndrome ◽  
And Behavior

Profiles of obesity in Prader-Willi syndrome

2014 ◽  
Vol 122 (03) ◽  
Author(s):  
E Bogova ◽  
N Volevodz ◽  
V Peterkova
Keyword(s):  
Prader Willi Syndrome
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