Micropuncture Study of Composition of Colloid in Rat Thyroid Acini.

1968 ◽  
Vol 46 (4) ◽  
pp. P-16-P-17 ◽  
Author(s):  
T Shagrin ◽  
JA Young
Keyword(s):  
Micropuncture Study ◽  
Rat Thyroid

Micropuncture Study of Glomerulotubular Balance in the Rat Kidney

Nephron ◽  
1969 ◽  
Vol 6 (3) ◽  
pp. 418-436 ◽  
Author(s):  
Elvira E. Arrizurieta-Muchnik ◽  
W.E. Lassiter ◽  
Eleanor M. Lipham ◽  
C.W. Gottschalk
Keyword(s):  
Rat Kidney ◽  
Micropuncture Study ◽  
Glomerulotubular Balance

scholarly journals Retraction for Fusco et al., “A mos Oncogene-Containing Retrovirus, Myeloproliferative Sarcoma Virus, Transforms Rat Thyroid Epithelial Cells and Irreversibly Blocks Their Differentiation Pattern”

2018 ◽  
Vol 92 (6) ◽  
pp. e02169-17
Author(s):  
Alfredo Fusco ◽  
Giuseppe Portella ◽  
Pier Paolo Di Fiore ◽  
Maria Teresa Berlingieri ◽  
Roberto Di Lauro ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Sarcoma Virus ◽  
Differentiation Pattern ◽  
Rat Thyroid

scholarly journals Characteristics of a lysosomal membrane transport system for tyrosine and other neutral amino acids in rat thyroid cells.

1986 ◽  
Vol 261 (36) ◽  
pp. 17107-17112
Author(s):  
J Bernar ◽  
F Tietze ◽  
L D Kohn ◽  
I Bernardini ◽  
G S Harper ◽  
...  
Keyword(s):  
Amino Acids ◽  
Membrane Transport ◽  
Transport System ◽  
Lysosomal Membrane ◽  
Thyroid Cells ◽  
Neutral Amino Acids ◽  
Rat Thyroid

scholarly journals Hormonal disregulation mechanism in the rat thyroid tumor induced by diniconazole.

1993 ◽  
Vol 18 (1) ◽  
pp. 57-67 ◽  
Author(s):  
Shunji HOSOKAWA ◽  
Jun NAKAMURA ◽  
Seiichi ITO ◽  
Masakazu MURAKAMI ◽  
Mariko INEYAMA ◽  
...  
Keyword(s):  
Thyroid Tumor ◽  
Rat Thyroid

scholarly journals Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells

Cells ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1518
Author(s):  
Maria Qatato ◽  
Vaishnavi Venugopalan ◽  
Alaa Al-Hashimi ◽  
Maren Rehders ◽  
Aaron D. Valentine ◽  
...  
Keyword(s):  
Cell Surface ◽  
Cell Lines ◽  
Human Thyroid ◽  
Apical Plasma Membrane ◽  
Thyroid Cell ◽  
Thyroid Cells ◽  
Trace Amine ◽  
Rat Thyroid

Trace amine-associated receptor 1 (rodent Taar1/human TAAR1) is a G protein-coupled receptor that is mainly recognized for its functions in neuromodulation. Previous in vitro studies suggested that Taar1 may signal from intracellular compartments. However, we have shown Taar1 to localize apically and on ciliary extensions in rodent thyrocytes, suggesting that at least in the thyroid, Taar1 may signal from the cilia at the apical plasma membrane domain of thyrocytes in situ, where it is exposed to the content of the follicle lumen containing putative Taar1 ligands. This study was designed to explore mouse Taar1 (mTaar1) trafficking, heterologously expressed in human and rat thyroid cell lines in order to establish an in vitro system in which Taar1 signaling from the cell surface can be studied in future. The results showed that chimeric mTaar1-EGFP traffics to the apical cell surface and localizes particularly to spherical structures of polarized thyroid cells, procilia, and primary cilia upon serum-starvation. Moreover, mTaar1-EGFP appears to form high molecular mass forms, possibly homodimers and tetramers, in stably expressing human thyroid cell lines. However, only monomeric mTaar1-EGFP was cell surface biotinylated in polarized human thyrocytes. In polarized rat thyrocytes, mTaar1-EGFP is retained in the endoplasmic reticulum, while cilia were reached by mTaar1-EGFP transiently co-expressed in combination with an HA-tagged construct of the related mTaar5. We conclude that Taar1 trafficking to cilia depends on their integrity. The results further suggest that an in vitro cell model was established that recapitulates Taar1 trafficking in thyrocytes in situ, in principle, and will enable studying Taar1 signaling in future, thus extending our general understanding of its potential significance for thyroid autoregulation.

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