THE DETERMINATION OF VITAMIN C BY THE GROWTH OF GUINEA-PIGS

1945 ◽  
Vol 23 (4) ◽  
pp. 281-287 ◽  
Author(s):  
Mary C Dawbarn
Keyword(s):  
Vitamin C ◽  
Guinea Pigs

scholarly journals The determination of vitamin C by means of its influence on the body weight of guinea-pigs

1936 ◽  
Vol 30 (9) ◽  
pp. 1719-1727 ◽  
Author(s):  
Katharine Hope Coward ◽  
Elsie Woodward Kassner
Keyword(s):  
Body Weight ◽  
Vitamin C ◽  
Guinea Pigs ◽  
The Body

Liver Histological Improvement After Administration of High-Dose Vitamin C in Guinea Pig with Nonalcoholic Steatohepatitis

2018 ◽  
Vol 88 (5-6) ◽  
pp. 263-269
Author(s):  
Seong-Hoon Park ◽  
A Lum Han ◽  
Na-Hyung Kim ◽  
Sae-Ron Shin
Keyword(s):  
Liver Biopsy ◽  
Vitamin C ◽  
Nonalcoholic Steatohepatitis ◽  
Guinea Pigs ◽  
Normal Diet ◽  
High Dose ◽  
Biochemical Tests ◽  
Deficient Diet ◽  
Histological Improvement ◽  
Vit C

Abstract. Background: Vitamin C is a strong antioxidant, and the health effects of vitamin C megadoses have not been validated despite the apparent health benefits. Therefore, the present study sought to confirm the effects of vitamin C megadoses. Materials and Methods : Four groups of six guinea pigs were used. Each group was fed one of the following diets for three weeks: normal diet, methionine choline-deficient diet, methionine choline-deficient diet + vitamin C megadose (MCD + vit C 2.5 g/kg/day), and methionine-choline deficient diet + ursodeoxycholic acid (MCD + UDCA 30 mg/kg/day). The MCD diet was given to induce nonalcoholic steatohepatitis, and UDCA was used to treat nonalcoholic steatohepatitis. Three weeks after initial diet administration, the results of biochemical tests and liver biopsy were compared between the groups. Results: The cytoplasm state was similar in the MCD + vit C and MCD + UDCA groups, exhibiting clearing of the cytoplasm and ballooning degeneration. However, macrovesicular steatosis was not observed in the MCD + vit C group. Aspartate transaminase and alanine transaminase were elevated significantly following vitamin C administration. Conclusions: The present study confirmed that alone vitamin C megadoses are potential remedies for nonalcoholic steatohepatitis, based on the liver biopsy results of guinea pigs that were unable to synthesize vitamin C.

Overpressured-layer chromatographic determination of ascorbigen (bound vitamin C) inBrassicavegetables

2004 ◽  
Vol 17 (5) ◽  
pp. 360-364 ◽  
Author(s):  
György Kátay ◽  
Zsolt Németh ◽  
Szilárd Szani ◽  
Oszkár Köck ◽  
Levente Albert ◽  
...  
Keyword(s):  
Vitamin C ◽  
Chromatographic Determination

A DETERMINATION OF THE AMOUNT OF VITAMIN C IN SOME MEDICAL PLANTS GROWING IN THE SOUTH– WESTERN ZARAFSHAN MOUNTAIN RANGES

2018 ◽  
pp. 48-49
Author(s):  
P. Mirkhamidova ◽  
U. E. Khujanazarov ◽  
D. A. Mamatqulov ◽  
S. Ziyamukhamedova ◽  
G. I. Mukhamedov
Keyword(s):  
Vitamin C ◽  
The South ◽  
Mountain Ranges ◽  
Medical Plants

INFLUENCE OF A PROLONGED PARTILA DEFICIENCY OF VITAMIN C ON THE RECOVERY OF GUINEA PIGS FROM INJURY TO BONES AND MUSCLES

Nature ◽  
1943 ◽  
Vol 151 (3831) ◽  
pp. 395-396 ◽  
Author(s):  
E. KODICEK ◽  
P. D. F. MURRAY
Keyword(s):  
Vitamin C ◽  
Guinea Pigs
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