scholarly journals Excessive variability in systolic blood pressure that is self-measured at home exacerbates the progression of brain white matter lesions and cognitive impairment in the oldest old

2015 ◽  
Vol 39 (4) ◽  
pp. 245-253 ◽  
Author(s):  
Zhendong Liu ◽  
Yingxin Zhao ◽  
Hua Zhang ◽  
Qiang Chai ◽  
Yi Cui ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cognitive Impairment ◽  
White Matter ◽  
Systolic Blood Pressure ◽  
Oldest Old ◽  
White Matter Lesions ◽  
Brain White Matter ◽  
At Home

scholarly journals Variability in Midlife Systolic Blood Pressure Is Related to Late-Life Brain White Matter Lesions

Stroke ◽  
2002 ◽  
Vol 33 (1) ◽  
pp. 26-30 ◽  
Author(s):  
Richard J. Havlik ◽  
Daniel J. Foley ◽  
Bryan Sayer ◽  
Kamal Masaki ◽  
Lon White ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
Systolic Blood Pressure ◽  
White Matter Lesions ◽  
Late Life ◽  
Brain White Matter

scholarly journals White Matter Lesions and Cognitive Impairment as Silent Cerebral Disease in Hypertension

2006 ◽  
Vol 6 ◽  
pp. 494-501 ◽  
Author(s):  
Cristina Sierra ◽  
Antonio Coca
Keyword(s):  
Blood Pressure ◽  
Cognitive Impairment ◽  
White Matter ◽  
Indirect Evidence ◽  
White Matter Lesions ◽  
Cerebral White Matter ◽  
Cognitive Changes ◽  
Cerebral Disease ◽  
Functional Changes ◽  
Cerebral White Matter Lesions

Although the pathogenesis and clinical significance of cerebral white matter lesions remain controversial, it is well established that age and hypertension are the most important factors related to the presence of these lesions. Hypertension is known to be the most important factor for developing stroke and vascular dementia. In addition, the presence of cerebral white matter lesions is an important prognostic factor for the development of stroke, and also for cognitive impairment and dementia. The mechanisms underlying hypertension-related cognitive changes are complex and are not yet fully understood. Correlations between cerebral white matter lesions and elevated blood pressure provide indirect evidence that structural and functional changes in the brain over time may lead to lowered cognitive functioning when blood pressure control is poor or lacking.Some authors have suggested that the presence of white matter lesions in hypertensive patients could be considered an early marker of brain damage.

Prevention of White-Matter Lesions Through Control of Cerebrovascular Risk Factors

2003 ◽  
Vol 15 (S1) ◽  
pp. 147-151 ◽  
Author(s):  
Charles DeCarli
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
Systolic Blood Pressure ◽  
Strong Association ◽  
Treatment Strategies ◽  
White Matter Lesions ◽  
Elevated Blood Pressure ◽  
Cerebral White Matter ◽  
Elevated Blood ◽  
Atherosclerotic Vascular Disease

Multiple epidemiological and brain imaging studies show a strong association between elevations in systolic blood pressure and lesions of cerebral white matter. The association between white-matter lesions and systolic blood pressure persists even if individuals are receiving treatment, suggesting that these individuals may be undertreated. In addition, these studies suggest that lesions of cerebral white matter may serve as markers for atherosclerotic vascular disease. Treatment strategies, therefore, should focus on early and aggressive management of elevated blood pressure, but definitions of elevated blood pressure may need to be revised downward to achieve best results.

scholarly journals Association between central systolic blood pressure, white matter lesions in cerebral MRI and carotid atherosclerosis

2009 ◽  
Vol 32 (10) ◽  
pp. 869-874 ◽  
Author(s):  
Isha Shrestha ◽  
Tetsuya Takahashi ◽  
Eiichi Nomura ◽  
Toshiho Ohtsuki ◽  
Tomohiko Ohshita ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
Systolic Blood Pressure ◽  
Carotid Atherosclerosis ◽  
White Matter Lesions ◽  
Cerebral Mri ◽  
Central Systolic Blood Pressure

P-126: Blood pressure and white matter lesions' volume in mild cognitive impairment: Evidence for groups with different genetic vulnerability

2007 ◽  
Vol 3 (3S_Part_2) ◽  
pp. S139-S139
Author(s):  
Samantha Galluzzi ◽  
Cristina Geroldi ◽  
Luisa Benussi ◽  
Roberta Ghidoni ◽  
Cristina Testa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
White Matter ◽  
White Matter Lesions ◽  
Genetic Vulnerability
Sign in / Sign up

Export Citation Format

Share Document