scholarly journals Effect of antihypertensive medication adherence on hospitalization for cardiovascular disease and mortality in hypertensive patients

2013 ◽  
Vol 36 (11) ◽  
pp. 1000-1005 ◽  
Author(s):  
Sukyoun Shin ◽  
Hyunjong Song ◽  
Sang-Kwon Oh ◽  
Kyung Eob Choi ◽  
Ho Kim ◽  
...  
2020 ◽  
Vol 8 ◽  
pp. 205031212098245
Author(s):  
Assefa Tola Gemeda ◽  
Lemma Demissie Regassa ◽  
Adisu Birhanu Weldesenbet ◽  
Bedasa Taye Merga ◽  
Nanti Legesse ◽  
...  

The foundation of controlling hypertension is adherence to antihypertensive medication adherence. This systematic review and meta-analysis aimed to assess the magnitude and associated factors of adherence to antihypertensive medication among adult hypertensive patients in Ethiopia. A comprehensible bibliographic searching was conducted from PubMed, EMBASE, Scopus, and Web of Science core collection. All published and unpublished studies that had been accessible before 31 May 2020, and written in English were eligible. Joanna Briggs Institute assessment tool was used to evaluate the quality of the findings of the included studies. Stata software 16.0 was used to analyze the data. Study-specific estimates were pooled to determine the overall prevalence estimate across studies using a random-effects meta-analysis model. Publication bias and heterogeneity were checked. Fourteen studies with a total of 4938 hypertensive patients were included in the final systematic review and meta-analysis. The pooled prevalence of medication adherence among hypertensive patients in Ethiopia was 65.41% (95% confidence interval: 58.91–71.91). Sub-group analysis shown that the pooled prevalence of medication adherence was the highest (69.07%, 95% confidence interval: 57.83–80.31, I2 = 93.51) among studies using questionnaire technique whereas the lowest in Morisky Medication Adherence Scale eight-items (60.66%, 95% confidence interval: 48.92–72.40, I2 = 97.16). Moreover, medication adherence was associated with the presence of comorbidities (pooled odds ratio = 0.23, 95% confidence interval: 0.07–0.38, p = 0.030, I2 = 54.9%) and knowledge about the disease and its management (pooled odds ratio = 2.98, 95% confidence interval: 1.72–4.24, p = 0.04, I2 = 55.55%) but not with place of residence (pooled odds ratio = 1.22, 95% confidence interval: 0.51–1.93, p = 0.00, I2 = 76.9%). Despite a lack of uniformity among included studies, adherence to antihypertensive medication among the hypertensive population in Ethiopia was moderate. The presence of comorbidities and/or complications reduced the odds of adherence whereas having good knowledge about the disease increased chance of medication adherence among hypertensive patients.


2020 ◽  
Vol 61 (3) ◽  
pp. 120
Author(s):  
UwemedimbukSmart Ekanem ◽  
EmemIme Dan ◽  
GeorgeGeorge Etukudo ◽  
IdongesitIbanga Ndon ◽  
EkeminiEssien Etebom ◽  
...  

2015 ◽  
Vol 33 (2) ◽  
pp. 412-420 ◽  
Author(s):  
Marie Krousel-Wood ◽  
Elizabeth Holt ◽  
Cara Joyce ◽  
Rachael Ruiz ◽  
Adriana Dornelles ◽  
...  

Hypertension ◽  
2020 ◽  
Vol 76 (Suppl_1) ◽  
Author(s):  
RAHUL CHOUDHARY ◽  
Dinesh K Gautam ◽  
Shashi M Sharma

Introduction: The prevalence of systemic hypertension has increased considerably in India over the past few decades from 5 percent to between 20-40 percent in urban population and 12-17 percent in rural population. Although there is availability of numerous affordable antihypertensive drugs, hypertension is still poorly controlled, leading to an epidemic of non-communicable diseases. Drug nonadherence is implicated as a major factor responsible for poorly controlled hypertension. Aim: This study was undertaken to gather data regarding drug adherence among hypertensive cohort and factors responsible for poor adherence. Methods: We prospectively studied 1468 hypertensive patients at a tertiary care hospital. Assessment of antihypertensive medication adherence was determined using the instrument validated by Morisky et al. Poor medication adherence was defined as answering yes to three or more of eight questions. Office reading and 24-hr ABPM were used to assess the level of hypertension control. Result: The mean age of the included patients was 61.2 ± 10.6 years and 63.5 % were male. Among the studied cohort, 55.8 % (819 out of 1468) patients were highly adherent to antihypertensive medication and adequate BP control was achieved in only 39.10 % (574 out of 1468) patients. Independent predictors of drug non-adherence in a multivariate analysis model were illiteracy (hazard ratio [HR] 3.06; 95% confidence interval [CI], 1.31-7.16), low socioeconomic status (HR 2.6; 95% CI, 1.28-4.89), presence of drug side effect (HR 1.7; 95% CI, 1.54-1.95), number of drugs (HR 1.8; 95% CI, 1.4-2.2), number of years on treatment (HR 1.4; 95% CI, 1.1-1.8), incognizant of long term risk of uncontrolled hypertension (HR 1.5; 95% CI, 1.31-1.74), irregular BP monitoring (HR 1.3; 95% CI, 1.1-1.6), and associated CKD and/or DM (HR 2.74; 95% CI, 1.065-7.05) Conclusion: Antihypertensive drug non adherence is a prevalent behavior among patients and since many of the attributed factors are modifiable, they signal opportunities to improve adherence, and thus, BP control in clinical practice


2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Saiful Nurhidayat

Abstract : Hypertension or high blood pressure is an abnormal increase in blood pressure in the arteries continuously over a period. The dangers of hypertension can lead to damage to various organs including kidneys, brain, heart, eye, causing vascular resistance and stroke. Hypertension takes care of the old and continuously. One effective way to lower blood pressure is to obediently take medicine so that it takes the role of families in monitoring patients taking the medication. With the participation of the family are expected to hypertension sufferers can be controlled. This study aims to determine the family's role in monitoring the adherence of hypertensive patients. The study was conducted in rural communities Slahung Ponorogo, a representative sample of 53 respondents taken by purposive sampling. Quantitative design with cross sectional design of the study the family's role in monitoring the adherence of hypertensive patients. Instruments in this study using questionnaires and observation sheets. The results of 53 respondents obtained the majority of the 29 respondents (55%) has the role of both families and 24 respondents (45%) families have a bad role in monitoring medication adherence. Age and education contribute to determining the role family. Intermediate (41-60 years old) and college education contribute to determining the role well. Conversely > 61 years of elementary education and contribute in a bad role.Keywords : the role of the family, medication adherence, hypertension. Abstrak : Hipertensi atau tekanan darah tinggi adalah suatu peningkatan abnormal tekanan darah dalam pembuluh darah arteri secara terus-menerus lebih dari suatu periode. Bahaya hipertensi dapat memicu rusaknya berbagai organ tubuh diantaranya: ginjal, otak, jantung, mata, menyebabkan resistensi pembuluh darah dan stroke. Penyakit hipertensi membutuhkan perawatan yang lama dan terus menerus. Salah satu cara yang efektif untuk menurunkan tekanan darah adalah dengan patuh minum obat sehingga dibutuhkan peran keluarga dalam memantau minum obat penderita. Dengan adanya peran serta keluarga diharapkan penyakit hipertensi penderita dapat terkontrol. Penelitian ini bertujuan untuk mengetahui peran keluarga dalam memantau kepatuhan minum obat penderita hipertensi. Penelitian dilakukan pada masyarakat desa Slahung Ponorogo,sampel representatif sejumlah 53 responden diambil secara Purposive Sampling. Desain kuantitatif dengan rancangan Cross sectional yang mempelajari peran keluarga dalam memantau kepatuhan minum obat penderita hipertensi. Instrumen pada penelitian ini menggunakan kuesioner dan lembar observasi. Hasil penelitian dari 53 responden didapatkan sebagian besar 29 responden (55 %) keluarga mempunyai peran baik dan 24 responden (45 %) keluarga mempunyai peran buruk dalam memantau kepatuhan minum obat. Faktor usia dan pendidikan berkontribusi dalam menentukan peran keluarga. Usia madya (41-60 tahun) dan jenjang pendidikan perguruan tinggi berkontribusi dalam menentukan peran baik. Sebaliknya > 61 tahun dan jenjang pendidikan SD berkontribusi dalam peran buruk.Kata Kunci : peran keluarga, kepatuhan minum obat, penyakit hipertensi.


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