scholarly journals Ganglion cell complex thickness in nonexudative age-related macular degeneration

Eye ◽  
2015 ◽  
Vol 29 (8) ◽  
pp. 1076-1080 ◽  
Author(s):  
E Yenice ◽  
A Şengün ◽  
G Soyugelen Demirok ◽  
E Turaçlı
Keyword(s):  
Ganglion Cell ◽  
Macular Degeneration ◽  
Cell Complex ◽  
Age Related Macular Degeneration ◽  
Ganglion Cell Complex ◽  
Age Related

Macular Ganglion Cell Complex and Retinal Nerve Fiber Layer Comparison in Different Stages of Age-Related Macular Degeneration

2015 ◽  
Vol 160 (3) ◽  
pp. 602-607.e1 ◽  
Author(s):  
Ilaria Zucchiatti ◽  
Maurizio Battaglia Parodi ◽  
Luisa Pierro ◽  
Maria Vittoria Cicinelli ◽  
Marco Gagliardi ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Macular Degeneration ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Cell Complex ◽  
Age Related Macular Degeneration ◽  
Ganglion Cell Complex ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Age Related

scholarly journals Ganglion Cell Complex Evaluation in Exudative Age-Related Macular Degeneration after Repeated Intravitreal Injections of Ranibizumab

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Andrea Perdicchi ◽  
Giacomo Peluso ◽  
Daniela Iacovello ◽  
Marco Balestrieri ◽  
Martina Delle Fave ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Statistical Significance ◽  
Clinical Results ◽  
Cell Complex ◽  
Age Related Macular Degeneration ◽  
Intravitreal Injections ◽  
Ganglion Cell Complex ◽  
Intravitreal Ranibizumab ◽  
Age Related ◽  
Wet Amd

Purpose. To detect the effects of intravitreal ranibizumab injections on GCC in patients with wet AMD.Methods. 32 wet AMD eyes were selected and submitted at three ranibizumab injections. RTVue-OCT GCC and MM5 protocol were performed before treatment and twenty days after each injection.Results. At baseline mean GCC thickness was 93.9 ± 18.5 μm. Twenty days after each intravitreal injection it was, respectively, 85.8 ± 10.1, 86.5 ± 9.3, and 91.1 ± 11.5 μm, without statistical significance. A significant improvement in visual acuity (P= 0.031) and a reduction of mean foveal (P= 0.001) and macular thickness (P= 0.001) were observed.Conclusion. The clinical results confirm therapeutic efficacy of intravitreal injections of ranibizumab in wet AMD. A contemporary not statistically significant reduction of GCC thickness suggests that the loading phase of ranibizumab does not have any toxic effects on ganglion cell complex.

scholarly journals Ganglion Cell Complex Evaluation in Exudative Age-Related Macular Degeneration after Repeated Intravitreal Injections of Ranibizumab

2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Andrea Perdicchi ◽  
Giacomo Peluso ◽  
Daniela Iacovello ◽  
Marco Balestrieri ◽  
Martina Delle Fave ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Statistical Significance ◽  
Clinical Results ◽  
Cell Complex ◽  
Age Related Macular Degeneration ◽  
Intravitreal Injections ◽  
Ganglion Cell Complex ◽  
Intravitreal Ranibizumab ◽  
Age Related ◽  
Wet Amd

Purpose. To detect the effects of intravitreal ranibizumab injections on GCC in patients with wet AMD.Methods. 32 wet AMD eyes were selected and submitted at three ranibizumab injections. RTVue-OCT GCC and MM5 protocol were performed before treatment and twenty days after each injection.Results. At baseline mean GCC thickness was 93.9 ± 18.5 μm. Twenty days after each intravitreal injection it was, respectively, 85.8 ± 10.1, 86.5 ± 9.3, and 91.1 ± 11.5 μm, without statistical significance. A significant improvement in visual acuity (P= 0.031) and a reduction of mean foveal (P= 0.001) and macular thickness (P= 0.001) were observed.Conclusion. The clinical results confirm therapeutic efficacy of intravitreal injections of ranibizumab in wet AMD. A contemporary not statistically significant reduction of GCC thickness suggests that the loading phase of ranibizumab does not have any toxic effects on ganglion cell complex.

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