scholarly journals Adequate iodine nutrition in Sweden: a cross-sectional national study of urinary iodine concentration in school-age children

2008 ◽  
Vol 63 (7) ◽  
pp. 828-834 ◽  
Author(s):  
M Andersson ◽  
G Berg ◽  
R Eggertsen ◽  
H Filipsson ◽  
E Gramatkovski ◽  
...  
2013 ◽  
Vol 1 (1) ◽  
pp. 38-41
Author(s):  
AK Nepal ◽  
S Gautam ◽  
S Khatiwada ◽  
PR Shakya ◽  
B Gelal ◽  
...  

Background: Iodine deficiency remains a significant health problem in developing countries, including Nepal.   Objective: This study was conducted to measure the iodine status of school children in two districts Dhankuta and Tehrathum of Eastern Nepal by estimating median urinary iodine concentration (UIC) as a population parameter in the school children. Materials and Methods: This cross-sectional study was conducted from August 2010 to July 2011 in school children (6-12 years of age) of two hilly districts of Eastern Nepal, Dhankuta and Tehrathum. A total of 154 school age children from the two districts were chosen for the study after obtaining written consent from their guardians and school authority. UIC was estimated in these school children by ammonium persulphate digestion microplate method. Results: Among the school age children selected for the study median inter-quartile range (IQR) of urinary iodine in Dhankuta (n=63) and Tehrathum (n=91) districts were 214.04 (126.44; 323.0) μg/L and 252.34 (161.81; 301.63) μg/L. No significant differences were observed between the median UIC of these two districts (p=0.235). Among the school children in Dhankuta districts 2(3.2%) were severely deficient, 4(6.3%) were moderately deficient and 6(9.5%) were mildly deficient. In Tehrathum district 2(2.2%) were moderately deficient and 5(5.5%) were mildly deficient. Conclusion: The present study showed improved iodine status with optimal levels of median urinary iodine concentration in the two districts, Dhankuta and Tehrathum of Eastern Nepal. Regular monitoring of population median urinary iodine concentration is recommended for sustainable optimal iodine nutrition.DOI: http://dx.doi.org/10.3126/stcj.v1i1.7986 Sunsari Technical College Journal Vol.1(1) 2012 38-41


2019 ◽  
Vol 25 (10) ◽  
pp. 987-993 ◽  
Author(s):  
Nicholas Hutchings ◽  
Elena Aghajanova ◽  
Sisak Baghdasaryan ◽  
Mushegh Qefoyan ◽  
Catherine Sullivan ◽  
...  

Objective: Iodine is a necessary nutrient for the synthesis of thyroid hormones and essential in human development. Being naturally deficient in iodine, Armenia launched a national universal salt iodization (USI) strategy in 2004. Although high rates of goiter continued to be reported, iodine status has not been studied since 2005. Therefore, this study sought to assess the current situation of population iodine nutrition in Armenia.Methods: We used a selective cross-sectional model to recruit three groups: school-age children (SAC), pregnant women (PW), and nonpregnant women of reproductive age (WRA) from each province. We collected casual urine and table salt samples from each participant, which were analyzed for iodine concentration. A repeat urine sample was collected in a subset of participants to adjust the results for within-person variation in iodine concentration. Group-wise urinary iodine concentrations (UICs) were compared with international reference criteria for iodine status.Results: Urine samples were collected from 1,125 participants from 13 different towns in Armenia; a total of 1,078 participants were included in the final analysis: 361 SAC (mean age, 10.5 years, 46.6% female), 356 PW (mean age, 26.1 years), and 361 WRA (mean age, 35.5 years). Population and geographically weighted median UIC were: SAC, 242 μg/L ([25th percentile] 203 to [75th percentile] 289 μg/L); PW, 226 μg/L (209 to 247 μg/L); WRA, 311 μg/L (244 to 371 μg/L). A total of 1,041 table salt samples were sufficient for laboratory analysis: 973 (93.4%) of the salt iodine measurements were within the national standard range of 40 ± 15 mg/kg.Conclusion: The results of household salt sampling indicated a successful USI strategy. While the present study did not achieve a truly representative sample of Armenia's population, the UIC results support the conclusion that iodine deficiency has not recurred and is not an underlying factor for any remaining high goiter prevalence in Armenia.Abbreviations: PW = pregnant women; SAC = school-age children; SI = salt iodine; UIC = urinary iodine concentration; USI = universal salt iodization; WHO = World Health Organization; WRA = women of reproductive age


2016 ◽  
Vol 14 (3) ◽  
pp. 350
Author(s):  
Renata De Oliveira Campos ◽  
Joaquim Custódio Silva Júnior ◽  
Elton Estrela Ramos

<p><strong><em>Introduction:</em></strong><em> iodine deficiency </em><em>disorders (IDD)</em><em> </em><em>are most common cause of preventable brain damage, mental retardation and stunted growth in children</em><em> worldwide. Several indicators are complementary to urinary iodine concentration (UIC) for assessing iodine nutritional status, as thyroid size, thyroglobulin (Tg) and thyroid stimulating hormone (TSH) concentrations in the blood.</em><strong><em> Objective:</em></strong><em> </em><em>analyze TSH in filter paper blood values and correlate with UIC in schoolchildren from public school at state of Bahia, Brazil</em><em>. <strong>Methodology: </strong></em><em>cross-sectional study was conducted in 880 schoolchildren aged 6-14 years, randomly selected, of public schools in five cities of four micro-regions of Bahia between October 2013 and September 2014. TSH was analyzed in filter-paper blood and UIC were measured by adapted Sandell-Kolthoff reaction. </em><strong><em>Results:</em></strong><em> 880 blood samples on filter-paper were analyzed for TSH. The reference range previously established is 0.72 to 6.0 </em><em>μ</em><em>UI/mL</em><em>. Results of this research TSH dosage ranged from 0.24 </em><em>μ</em><em>IU/L to</em><em> 7.71 </em><em>μ</em><em>IU/L,</em><em> with a mean of 1.01±0.55 </em><em>μ</em><em>UI/L</em><em> and median 0.89 </em><em>μ</em><em>UI/L</em><em>. Only one child presented TSH greater than 6.0 (7.71 </em><em>μ</em><em>IU/L); however, results of urinary iodine were consistent with a more than adequate nutrition iodine (243.70</em><em>μ</em><em>g/L). There’ no correlation between TSH and UIC (r= 0.115; p= 0.002)</em><em>.</em><em> </em><strong><em>Conclusion:</em></strong><em>  in the present study, schoolchildren showed low values of TSH, but the mean UIC was indicative of adequate iodine nutrition</em><em>.</em><em></em></p>


2016 ◽  
Vol 9 (1) ◽  
pp. 38
Author(s):  
Md. Anowar Hossain ◽  
M. Abul Hasanat ◽  
Murshed Ahamed Khan ◽  
Jobaida Naznin ◽  
Kazi Ashraful Alam ◽  
...  

<p><strong>Background:</strong> Iodine deficiency disorders (IDD) are common nutritional problem globally. All groups of people are affected by it, but the pregnant women and their neonates are most vulnerable.</p><p><strong>Objectives:</strong> This study was carried out to see the iodine status of pregnant women using median urinary iodine concentration (MUI) as a measure of outcome. Methods: This cross sectional observational study assessed the MUI in casual urine samples from 225 pregnant women (75 pregnants from each trimester) and 75 non-pregnant healthy controls. The urinary iodine content was estimated in urine sample using the method of Dunn et al. with the modification of Sandell &amp; Kolthoff (wet digestion method).</p><p><strong>Results:</strong> Median value of urinary iodine in pregnant women was 48.21Ug/L compared to 52.27</p>


2019 ◽  
Vol 110 (4) ◽  
pp. 949-958 ◽  
Author(s):  
Molla Mesele Wassie ◽  
Philippa Middleton ◽  
Shao Jia Zhou

ABSTRACT Background Population iodine deficiency is indicated by >3% of the population with newborn thyroid-stimulating hormone (TSH) concentration >5 mIU/L, median urinary iodine concentration (MUIC) <100 µg/L, or >5% prevalence of goiter in school-age children. However, the agreement between these population markers has not been systematically investigated. Objective To assess the agreement between TSH, MUIC, and goiter as markers of population iodine status. Methods We performed a systematic search for studies published on PubMed, Scopus, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase, and PsycINFO up to 29 October, 2018. Studies assessing iodine status in the population using the TSH marker and either MUIC or goiter prevalence in school-age children were included. The agreement between markers in classifying iodine status of the population was assessed. The sensitivity and specificity of the TSH marker was determined against MUIC and goiter prevalence as the reference markers. Results Of 17,435 records identified by the search strategy, 57 eligible studies were included in the review. The agreement between markers in classifying the iodine status of populations into the same category was 65% for TSH and MUIC, and 83% for TSH and goiter prevalence. The TSH marker had a sensitivity of 0.75 and specificity of 0.53 when compared with MUIC, and 0.86 and 0.50 when compared with goiter prevalence. Conclusions The TSH marker has a better agreement with goiter prevalence than MUIC when classifying the iodine status of populations. Re-evaluation of the current criteria for classifying the iodine status of populations using the TSH marker is warranted. This systematic review was registered at PROSPERO (http://www.crd.york.ac.uk/prospero/) as CRD42018091247.


Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1404
Author(s):  
Xiaoyun Shan ◽  
Changqing Liu ◽  
Xiaoyan Luo ◽  
Yan Zou ◽  
Lichun Huang ◽  
...  

We evaluated the iodine nutritional status and related factors among school-age children based on the 2016 National Nutrition and Health Surveillance of Children and Lactating Women; 3808 children from Hebei, Guangxi, and Zhejiang province were included in the study. Urinary iodine concentration (UIC), thyroid-stimulating hormone (TSH), body mass index (BMI), vitamin A (VA), and vitamin D (VD) were measured. The abnormal rate of UIC and TSH were assessed. Relationships between UIC/TSH and the possible factors were analyzed. The overall median UIC was 185.14 µg/L, and the median UIC of children aged 8–10 was 164.60 µg/L. Prevalence of iodine deficiency and excess was 13.84% and 14.36%, respectively, and 12.87% of children showed TSH excess. UIC, as well as the abnormal rates of iodine deficiency (ID) and TSH, were significantly different among the three provinces. The median UICs and excess rates increased with age, reaching 211.45 µg/L and 21.35% at age of 14~, while TSH showed the opposite trend. Overweight children tended to have lower UIC and higher TSH. Higher UIC and TSH were found in VA sufficient group (p < 0.01). Further, the VD deficient group had a higher TSH compared to the sufficient group (p < 0.01). Moreover, UI and TSH distribution was obviously different among different vitamin A/D status (p < 0.05). Although the median UIC of school-age children was optimal, there were pockets of inadequate and excessive UI in the three provinces. Compared to the national IDD monitoring results in 2014, the iodine nutritional status of children was greatly improved. Considerations of region, age, BMI, VA, or VD are needed in the future iodine evaluation and surveillance.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Man Kumar Tamang ◽  
Basanta Gelal ◽  
Binaya Tamang ◽  
Madhab Lamsal ◽  
David Brodie ◽  
...  

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