scholarly journals The α7-nicotinic receptor is upregulated in immune cells from HIV-seropositive women: consequences to the cholinergic anti-inflammatory response

2015 ◽  
Vol 4 (12) ◽  
pp. e53 ◽  
Author(s):  
Manuel Delgado-Vélez ◽  
Carlos A Báez-Pagán ◽  
Yamil Gerena ◽  
Orestes Quesada ◽  
Laura I Santiago-Pérez ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Immune Cells ◽  
Nicotinic Receptor ◽  
Anti Inflammatory ◽  
Hiv Seropositive

scholarly journals Hydroalcoholic extract from Origanum vulgare induces a combined anti-mycobacterial and anti-inflammatory response in innate immune cells

PLoS ONE ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. e0213150 ◽  
Author(s):  
Federica De Santis ◽  
Noemi Poerio ◽  
Angelo Gismondi ◽  
Valentina Nanni ◽  
Gabriele Di Marco ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Immune Cells ◽  
Innate Immune ◽  
Innate Immune Cells ◽  
Origanum Vulgare ◽  
Hydroalcoholic Extract ◽  
Anti Inflammatory

A new paradigm for a new simple chemical: butyrate & immune regulation

2021 ◽  
Author(s):  
Guoqi Dang ◽  
Weida Wu ◽  
Hongfu Zhang ◽  
Nadia Everaert
Keyword(s):  
Inflammatory Response ◽  
Histone Deacetylase ◽  
Immune Cells ◽  
Immune Regulation ◽  
Host Immunity ◽  
New Paradigm ◽  
Simple Chemical ◽  
Anti Inflammatory

Butyrate has attracted a lot of attention on host immunity. It promotes anti-inflammatory response by interacting with receptors, immune cells and suppressing histone deacetylase activity.

Compensatory anti-inflammatory response syndrome

2009 ◽  
Vol 101 (01) ◽  
pp. 36-47 ◽  
Author(s):  
Jean-Marc Cavaillon ◽  
Minou Adib-Conquy
Keyword(s):  
Inflammatory Response ◽  
Immune Cells ◽  
Immune Status ◽  
Regulatory Mechanisms ◽  
Experimental Procedure ◽  
Intensive Care Patients ◽  
Major Consequence ◽  
Enhanced Sensitivity ◽  
Anti Inflammatory ◽  
Global Defect

SummaryThe concept of ‘Compensatory anti-inflammatory response syndrome’ (CARS) was proposed in 1997 by Roger Bone (1941–1997) to qualify the consequences of the counter-regulatory mechanisms initiated to limit the overzealous inflammatory process in patients with infectious (sepsis) or non-infectious systemic inflammatory response syndrome (SIRS). One major consequence of CARS is the modification of the immune status that could favour the enhanced susceptibility of intensive care patients to nosocomial infections. Indeed, most animal ‘two-hit’ models illustrate an enhanced sensitivity to infection after a first insult. However, this observation is highly dependent on the experimental procedure. Numerous functions of circulating leukocytes are altered in sepsis and SIRS patients, as well as in animal models of sepsis or SIRS. However, this is rather a reprogramming of circulating leukocytes, since there is not a global defect of the immune cells functions. Furthermore, within tissues, leukocytes are rather primed or activated than immunosuppressed. Thus, CARS may be considered as an adapted compartmentalized response with the aim to silence some acute proinflammatory genes, and to maintain the possible expression of certain genes involved in the anti-infectious process.

scholarly journals Obesity-Associated Inflammation: Does Curcumin Exert a Beneficial Role?

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 1021
Author(s):  
Rosaria Varì ◽  
Beatrice Scazzocchio ◽  
Annalisa Silenzi ◽  
Claudio Giovannini ◽  
Roberta Masella
Keyword(s):  
Adipose Tissue ◽  
Inflammatory Response ◽  
Chronic Diseases ◽  
Immune Cells ◽  
Molecular Mechanisms ◽  
Curcuma Longa ◽  
Low Grade ◽  
Obese People ◽  
Cytokines And Chemokines ◽  
Anti Inflammatory

Curcumin is a lipophilic polyphenol, isolated from the plant turmeric of Curcuma longa. Curcuma longa has always been used in traditional medicine in Asian countries because it is believed to have numerous health benefits. Nowadays it is widely used as spice component and in emerging nutraceutical food worldwide. Numerous studies have shown that curcumin possesses, among others, potential anti-inflammatory properties. Obesity represents a main risk factor for several chronic diseases, including type 2 diabetes, cardiovascular disease, and some types of cancer. The establishment of a low-grade chronic inflammation, both systemically and locally in adipose tissue, occurring in obesity most likely represents a main factor in the pathogenesis of chronic diseases. The molecular mechanisms responsible for the onset of the obesity-associated inflammation are different from those involved in the classic inflammatory response caused by infections and involves different signaling pathways. The inflammatory process in obese people is triggered by an inadequate intake of nutrients that produces quantitative and qualitative alterations of adipose tissue lipid content, as well as of various molecules that act as endogenous ligands to activate immune cells. In particular, dysfunctional adipocytes secrete inflammatory cytokines and chemokines, the adipocytokines, able to recruit immune cells into adipose tissue, amplifying the inflammatory response also at systemic level. This review summarizes the most recent studies focused at elucidating the molecular targets of curcumin activity responsible for its anti-inflammatory properties in obesity-associated inflammation and related pathologies.

scholarly journals Oviduct epithelium induces interferon-tau in bovine Day-4 embryos, which generates an anti-inflammatory response in immune cells

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Anup K. Talukder ◽  
Mohammad B. Rashid ◽  
Mohamed S. Yousef ◽  
Kazuya Kusama ◽  
Takashi Shimizu ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Immune Cells ◽  
Interferon Tau ◽  
Oviduct Epithelium ◽  
Anti Inflammatory
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