scholarly journals Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis

Cell Research ◽  
2009 ◽  
Vol 19 (7) ◽  
pp. 802-815 ◽  
Author(s):  
Jianxin Lu ◽  
Lokendra Kumar Sharma ◽  
Yidong Bai
Keyword(s):  
Mitochondrial Dna ◽  
Mitochondrial Dysfunction ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations

Do mitochondrial DNA mutations have a role in neurodegenerative disease?

2007 ◽  
Vol 35 (5) ◽  
pp. 1232-1235 ◽  
Author(s):  
K.J. Krishnan ◽  
A.K. Reeve ◽  
D.M. Turnbull
Keyword(s):  
Mitochondrial Dna ◽  
Mitochondrial Dysfunction ◽  
Neurodegenerative Disease ◽  
Mitochondrial Function ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations ◽  
A Cell ◽  
Eventual Death ◽  
Secondary Consequence

A decline in mitochondrial function has long been shown to exist in neurodegenerative disease. Whether this decline is a secondary consequence of other factors or whether it causes the eventual death of a cell is unknown. In this review, we will discuss some of the major evidence surrounding mitochondrial DNA mutations leading to mitochondrial dysfunction in neurodegenerative disease and discuss their possible role in neurodegeneration.

Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss

2007 ◽  
Vol 226 (1-2) ◽  
pp. 185-193 ◽  
Author(s):  
Tatsuya Yamasoba ◽  
Shinichi Someya ◽  
Chikako Yamada ◽  
Richard Weindruch ◽  
Tomas A. Prolla ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Mitochondrial Dna ◽  
Mitochondrial Dysfunction ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations ◽  
Age Related ◽  
Age Related Hearing Loss

scholarly journals Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

PLoS ONE ◽  
2010 ◽  
Vol 5 (7) ◽  
pp. e11468 ◽  
Author(s):  
Asimina Hiona ◽  
Alberto Sanz ◽  
Gregory C. Kujoth ◽  
Reinald Pamplona ◽  
Arnold Y. Seo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Mitochondrial Dna ◽  
Mitochondrial Dysfunction ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations
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