scholarly journals Mitochondrial DNA Mutations in Grade II and III Glioma Cell Lines Are Associated with Significant Mitochondrial Dysfunction and Higher Oxidative Stress

2017 ◽  
Vol 8 ◽  
Author(s):  
Bee Hong Soon ◽  
Nor Azian Abdul Murad ◽  
Sue-Mian Then ◽  
Azizi Abu Bakar ◽  
Farizal Fadzil ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Dna ◽  
Mitochondrial Dysfunction ◽  
Cell Lines ◽  
Glioma Cell ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations ◽  
Glioma Cell Lines ◽  
Grade Ii

scholarly journals Oxidative Stress Is Not a Major Contributor to Somatic Mitochondrial DNA Mutations

PLoS Genetics ◽  
2014 ◽  
Vol 10 (2) ◽  
pp. e1003974 ◽  
Author(s):  
Leslie S. Itsara ◽  
Scott R. Kennedy ◽  
Edward J. Fox ◽  
Selina Yu ◽  
Joshua J. Hewitt ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Dna ◽  
Major Contributor ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations

Oxidative stress is not an obligate mediator of disease provoked by mitochondrial DNA mutations

2001 ◽  
Vol 474 (1-2) ◽  
pp. 35-45 ◽  
Author(s):  
Justin L. Mott ◽  
Dekui Zhang ◽  
Melissa Stevens ◽  
Shin-Wen Chang ◽  
Grace Denniger ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mitochondrial Dna ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations

Do mitochondrial DNA mutations have a role in neurodegenerative disease?

2007 ◽  
Vol 35 (5) ◽  
pp. 1232-1235 ◽  
Author(s):  
K.J. Krishnan ◽  
A.K. Reeve ◽  
D.M. Turnbull
Keyword(s):  
Mitochondrial Dna ◽  
Mitochondrial Dysfunction ◽  
Neurodegenerative Disease ◽  
Mitochondrial Function ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations ◽  
A Cell ◽  
Eventual Death ◽  
Secondary Consequence

A decline in mitochondrial function has long been shown to exist in neurodegenerative disease. Whether this decline is a secondary consequence of other factors or whether it causes the eventual death of a cell is unknown. In this review, we will discuss some of the major evidence surrounding mitochondrial DNA mutations leading to mitochondrial dysfunction in neurodegenerative disease and discuss their possible role in neurodegeneration.

Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss

2007 ◽  
Vol 226 (1-2) ◽  
pp. 185-193 ◽  
Author(s):  
Tatsuya Yamasoba ◽  
Shinichi Someya ◽  
Chikako Yamada ◽  
Richard Weindruch ◽  
Tomas A. Prolla ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Mitochondrial Dna ◽  
Mitochondrial Dysfunction ◽  
Mitochondrial Dna Mutations ◽  
Dna Mutations ◽  
Age Related ◽  
Age Related Hearing Loss
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