scholarly journals Cycles of transient high-dose cyclophosphamide administration and intratumoral oncolytic adenovirus vector injection for long-term tumor suppression in Syrian hamsters

2014 ◽  
Vol 21 (4) ◽  
pp. 171-178 ◽  
Author(s):  
D Dhar ◽  
K Toth ◽  
W S M Wold
Keyword(s):  
Tumor Suppression ◽  
Adenovirus Vector ◽  
Oncolytic Adenovirus ◽  
High Dose ◽  
Syrian Hamsters ◽  
Cyclophosphamide Administration

scholarly journals INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies

2009 ◽  
Vol 16 (8) ◽  
pp. 625-637 ◽  
Author(s):  
B Ying ◽  
K Toth ◽  
J F Spencer ◽  
J Meyer ◽  
A E Tollefson ◽  
...  
Keyword(s):  
Adenovirus Vector ◽  
Oncolytic Adenovirus ◽  
Syrian Hamsters ◽  
Biodistribution Studies

scholarly journals 642. Toxicological Findings with Oncolytic Adenovirus Vector VRX-007, Wild-Type Ad5, and a Replication-Defective Adenovirus Vector in Syrian Hamsters and C57BL/6 Mice

2006 ◽  
Vol 13 ◽  
pp. S247
Author(s):  
Karoly Toth ◽  
Jacqueline F. Spencer ◽  
Drew L. Lichtenstein ◽  
Ann E. Tollefson ◽  
Debabrata Patra ◽  
...  
Keyword(s):  
Adenovirus Vector ◽  
Oncolytic Adenovirus ◽  
Wild Type ◽  
Syrian Hamsters ◽  
Replication Defective Adenovirus

[18F]Fluoride PET Indicates Reduced Bone Formation in Severe Glucocorticoid-induced Osteoporosis

1998 ◽  
Vol 37 (02) ◽  
pp. 76-79 ◽  
Author(s):  
T. D. Kirchhoff ◽  
W. Burchert ◽  
J. v. d. Hoff ◽  
H. Zeidler ◽  
H. Hundeshagen ◽  
...  
Keyword(s):  
Bone Formation ◽  
Multiple Organ ◽  
High Dose ◽  
Multiple Fractures ◽  
Glucocorticoid Treatment ◽  
Organ Manifestations ◽  
Diagnostic Benefit ◽  
Sharp Syndrome ◽  
18F Fluoride

SummaryA 61-year-old female patient presenting with mixed connective tissue disease (Sharp syndrome), underwent a long-term high dose glucocorticoid treatment because of multiple organ manifestations. Under steroid therapy she developed severe osteoporosis resulting in multiple fractures. A dynamic [18F]fluoride PET study in this patient revealed reduced fluoride influx in non-fractured vertebrae. This finding corresponds to pathogenetic concepts which propose an inhibition of bone formation as major cause of glucocorticoid-induced osteoporosis. In the light of the presented case it seems to be promising to evaluate the diagnostic benefit of [18F]fluoride PET in osteoporosis.

High-dose glucocorticoid therapy impairs long-term memory, but not executive function

2005 ◽  
Vol 113 (08) ◽  
Author(s):  
R Brunner ◽  
D Schaefer ◽  
K Hess ◽  
P Parzer ◽  
F Resch ◽  
...  
Keyword(s):  
Executive Function ◽  
Glucocorticoid Therapy ◽  
Long Term Memory ◽  
High Dose ◽  
Term Memory
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