scholarly journals TRPA1 channel mediates organophosphate-induced delayed neuropathy

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Qiang Ding ◽  
Sui Fang ◽  
Xueqin Chen ◽  
Youxin Wang ◽  
Jian Li ◽  
...  
Keyword(s):  
Delayed Neuropathy

Biochemical and Morphological Validation of a Rodent Model of Organophosphorus-Induced Delayed Neuropathy

1988 ◽  
Vol 4 (3) ◽  
pp. 361-371 ◽  
Author(s):  
Stephanie Padilla ◽  
Bellina Veronesi
Keyword(s):  
Data Base ◽  
Experimental Model ◽  
Nerve Fibers ◽  
Rodent Model ◽  
Experimental Literature ◽  
Delayed Neuropathy

Exposure to certain organophosphates (OPs) produces a delayed degeneration of the longest and largest nerve fibers (OPIDN). Until recently, investigators have used the chicken as the primary experimental model of OPIDN. Although the chicken is extremely sensitive to the ataxia associated with this neuropathy, it lacks an extensive biochemical, electrophysiological and pathological data-base. Because of this we set out to develop a rodent model of OPIDN with morphological and biochemical correlates similar to those seen in the chicken. Historically the rat had been labeled insensitive to OPIDN because of its lack of demonstrable ataxia in response to the neuropathic OPs. This paper describes the validation of a rodent model with biochemical and morphological endpoints similar to those described in the clinical and experimental literature for other models of OPIDN.

Carbofuran-Induced Delayed Neuropathy

2000 ◽  
Vol 38 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Po-Yi Yang ◽  
Thomas C.Y. Tsao ◽  
Ja-Liang Lin ◽  
Rong-Kuo Lyu ◽  
Ping-Cherng Chiang
Keyword(s):  
Delayed Neuropathy

Organophosphate-Induced Delayed Neuropathy

2003 ◽  
pp. 17-27 ◽  
Author(s):  
Marion Ehrich ◽  
Bernard S. Jortner
Keyword(s):  
Delayed Neuropathy

Organophosphate induced delayed neuropathy in genetically dissimilar chickens: studies with tri-ortho-cresyl phosphate (TOCP) and trichlorfon

2002 ◽  
Vol 136 (2) ◽  
pp. 143-150 ◽  
Author(s):  
Georgino Honorato de Oliveira ◽  
Vanessa Moreira ◽  
Sheila Patricia Ribeiro Goes
Keyword(s):  
Delayed Neuropathy

Phenylmethylsulfonyl fluoride protects against the degradation of neurofilaments in tri-ortho-cresyl phosphate (TOCP) induced delayed neuropathy

Toxicology ◽  
2009 ◽  
Vol 262 (3) ◽  
pp. 258-264 ◽  
Author(s):  
Fuyong Song ◽  
Yongjian Yan ◽  
Xiulan Zhao ◽  
Dandan Dou ◽  
Cuili Zhang ◽  
...  
Keyword(s):  
Phenylmethylsulfonyl Fluoride ◽  
Delayed Neuropathy

Murine susceptibility to organophosphorus-induced delayed neuropathy (OPIDN)

1991 ◽  
Vol 107 (2) ◽  
pp. 311-324 ◽  
Author(s):  
Bellina Veronesi ◽  
Stephanie Padilla ◽  
Kate Blackmon ◽  
Carey Pope
Keyword(s):  
Delayed Neuropathy
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