Clinical and toxicological investigations of a case of delayed neuropathy in man after acute poisoning by an organophosphorus pesticide

1978 ◽  
Vol 40 (4) ◽  
pp. 279-284 ◽  
Author(s):  
R. Hierons ◽  
M. K. Johnson
Keyword(s):  
Organophosphorus Pesticide ◽  
Acute Poisoning ◽  
Delayed Neuropathy

Plasma cholinesterase: double-edged parameter in the diagnosis of acute organophosphorus poisoning

2010 ◽  
Vol 50 (3) ◽  
pp. 159-160 ◽  
Author(s):  
D R Mahadeshwara Prasad ◽  
Hareesh S Gouda ◽  
Vinay R Hallikeri
Keyword(s):  
Biochemical Marker ◽  
Organophosphorus Pesticides ◽  
Clinical Signs ◽  
Organophosphorus Pesticide ◽  
Signs And Symptoms ◽  
Acute Poisoning ◽  
Plasma Cholinesterase ◽  
Pesticide Poisoning ◽  
Organophosphorus Poisoning ◽  
Clinical Signs And Symptoms

Biochemical markers are one of the mainstays in the diagnosis of ill health. Plasma cholinesterase is one such marker of the ill health caused by acute organophosphorus pesticide poisoning. Organophosphorus pesticides are powerful inhibitors of plasma cholinesterase; consequently, the reduced level of this biochemical marker has been used in the diagnosis of cases of acute poisoning. But how dependable is this biochemical marker in the diagnosis of suspected organophosphorus pesticide poisoning without adequate clinical signs and symptoms? In the case reported here, the low level of plasma cholinesterase which was suspected to be due to organophosphorus poisoning was found to be caused by pulmonary Koch's and hepatitis B with associated malnutrition.

scholarly journals Study of the Effect of Air to Fuel Ratio Parameter on the Organophosphorus – Pesticide Analysis by GC-FPD

2014 ◽  
Vol 36 ◽  
pp. 236-248
Author(s):  
A.Y. Kilany ◽  
Mohamed A. Elsayed ◽  
M.K. Abd El Megid ◽  
M.S. Fayed
Keyword(s):  
Dynamic Range ◽  
Organophosphorus Pesticides ◽  
Organophosphorus Pesticide ◽  
Acute Poisoning ◽  
Present Contribution ◽  
Flame Photometric Detector ◽  
Fuel Ratio ◽  
Relative Flow Rate ◽  
Photometric Detector ◽  
Relative Standard

In the present contribution, sensitive and precise method for the quantification of Organophosphorus / Pesticides (Malathion and Dimethoate) in nanograms range has been developed. The performance of flame photometric detector (FPD), a selective detector (P&S-mode) that can be used in the analysis of organophosphorus compound, is evaluated in terms of sensitivity, selectivity and reproducibility. The performance of flame photometric detector was strongly depending on the absolute and relative flow rate of air and hydrogen gases. The optimum air-to-fuel ratio for detection of Malathion and Dimethoate was 0.4 and 0.3 (FPD-P mode). At this ratio, low picogram amounts of phosphor can be detected accurately (0.18 pgP) with a wide linear dynamic range of 0.18 pgP to 298 ngP. While, the optimum air-to-fuel ratio, for detection of Malathion and Dimethoate was 0.6 (FPD-S mode). In addition to, the method is precise with 4.5 % relative standard deviation (RSD). In conclusion, it could be proposed that this procedure can be recommended as a suitable method for the quantification of Malathion and Dimethoate in cases of acute poisoning.

PRO-INFLAMMATORY CYTOKINS AND LACTOFERRINE IN BLOOD OF RATS AT AN ACUTE POISONING WITH DELTAMETRIN AND AT THE ENTEROSORBTION

2013 ◽  
pp. 100-104
Author(s):  
V.A. Likholobov ◽  
◽  
Yu.N. Fedorov ◽  
L.G. P'yanova ◽  
L.K. Gerunova ◽  
...  
Keyword(s):  
Acute Poisoning

Study of acute poisoning cases at tertiary care teaching hospital

2020 ◽  
Vol 13 (2) ◽  
pp. 18-21
Author(s):  
Mohammed Liyaqat Shareef ◽  
◽  
Mohammed Taqiuddin Khan ◽  
Keyword(s):  
Teaching Hospital ◽  
Tertiary Care ◽  
Acute Poisoning ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching

A structural analysis of acute exotoxicoses in people of elderly and senile age

2017 ◽  
pp. 10-14 ◽  
Author(s):  
K. K. Ilyashenko ◽  
A. Yu. Simonova ◽  
M. V. Belova
Keyword(s):  
Emergency Medicine ◽  
Structural Analysis ◽  
Suicide Attempt ◽  
Medical Records ◽  
Age Groups ◽  
Acute Poisoning ◽  
Frequent Reason ◽  
Research Institute

Based on the analysis of reports of the Department for treatment of acute poisonings at the N.V. Sklifosovskiy Research Institute of Emergency Medicine from 2009 to 2014 and medical records of in-patients hospitalized during that period, the structure of acute poisoning in elderly and senile patients was investigated. The share of patients of the senior age groups averages 12.5% of all patients. The most frequent reason for poisoning is a suicide attempt-71.9%. Psychopharmacological (46.5%) and cardiotropic (13.6%,) medications take the key place in poisonings as well as combined poisonings. The lethality analysis revealed its growth with increase in age of victims. One of the main causes of lethal outcomes is pneumonia.

Acute poisoning in children

1999 ◽  
Vol 75 (8) ◽  
pp. 244-50 ◽  
Author(s):  
Cláudio Schvartsman ◽  
Samuel Schvartsman
Keyword(s):  
Acute Poisoning ◽  
Poisoning In Children

scholarly journals Clinical characteristics and treatment of mixed-pesticide poisoning in a patient: reflections on a particular case

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097739
Author(s):  
Yiming Tao ◽  
Tingting Liu ◽  
Jie Han ◽  
Xiangdong Jian ◽  
Baotian Kan
Keyword(s):  
Medical History ◽  
Intramuscular Injection ◽  
Clinical Symptoms ◽  
Delayed Diagnosis ◽  
Acute Poisoning ◽  
Assisted Ventilation ◽  
Pesticide Poisoning ◽  
Methods Of Suicide ◽  
Commit Suicide ◽  
Careful Physical Examination

Patients who commit suicide often deliberately hide their medical history. Given that taking pesticides is one of the most common methods of suicide, other forms of poisoning may be neglected in clinical practice. We report here a case of mixed-pesticide poisoning. The patient was poisoned by oral administration of a coumarin rodenticide in combination with an intramuscular injection of organophosphorus (OP) pesticide. The patient was treated with vitamin K1, cholinesterase reactivators, atropine, ventilator-assisted ventilation, and bedside debridement. Her condition gradually stabilized and she eventually recovered and was discharged. Assessment of the causes of delayed diagnosis and treatment suggests that we need to improve early detection and treatment of acute poisoning. It is especially important to ask about the patient’s medical history, conduct a careful physical examination, and track the clinical symptoms and differential diagnosis of common poisoning. In addition to the three common routes of poisoning—oral, inhalation, and cutaneous mucosal contact—intramuscular injection of OP can also lead to severe poisoning, which manifests as respiratory failure.

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