scholarly journals Schwann cell precursors as a source for adrenal gland chromaffin cells

2017 ◽  
Vol 8 (10) ◽  
pp. e3072-e3072 ◽  
Author(s):  
Luiza Lousado ◽  
Pedro H D M Prazeres ◽  
Julia P Andreotti ◽  
Ana E Paiva ◽  
Patrick O Azevedo ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Adrenal Gland ◽  
Chromaffin Cells ◽  
Schwann Cell Precursors

scholarly journals Schwann Cell Precursors Generate the Majority of Chromaffin Cells in Zuckerkandl Organ and Some Sympathetic Neurons in Paraganglia

2019 ◽  
Vol 12 ◽  
Author(s):  
Maria Eleni Kastriti ◽  
Polina Kameneva ◽  
Dmitry Kamenev ◽  
Viacheslav Dyachuk ◽  
Alessandro Furlan ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Chromaffin Cells ◽  
Sympathetic Neurons ◽  
Schwann Cell Precursors

Multipotent Schwann Cell Precursors Generate Steroid-Producing Cells of the Adrenal Cortex and Chromaffin Cells of the Adrenal Medulla

2021 ◽  
Author(s):  
Charlotte Steenblock ◽  
Ilona Berger ◽  
Alice Santambrogio ◽  
Susanne Reinhardt ◽  
Mathias Lesche ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Adrenal Cortex ◽  
Adrenal Medulla ◽  
Chromaffin Cells ◽  
Schwann Cell Precursors

scholarly journals Nerve-associated Schwann cell precursors contribute extracutaneous melanocytes to the heart, inner ear, supraorbital locations and brain meninges

2021 ◽  
Author(s):  
Marketa Kaucka ◽  
Bara Szarowska ◽  
Michaela Kavkova ◽  
Maria Eleni Kastriti ◽  
Polina Kameneva ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Inner Ear ◽  
Gene Knockout ◽  
Hair Follicles ◽  
Lineage Tracing ◽  
Pigment Cells ◽  
Hearing Function ◽  
Embryonic Origin ◽  
Schwann Cell Precursors ◽  
Evolutionary Aspects

AbstractMelanocytes are pigmented cells residing mostly in the skin and hair follicles of vertebrates, where they contribute to colouration and protection against UV-B radiation. However, the spectrum of their functions reaches far beyond that. For instance, these pigment-producing cells are found inside the inner ear, where they contribute to the hearing function, and in the heart, where they are involved in the electrical conductivity and support the stiffness of cardiac valves. The embryonic origin of such extracutaneous melanocytes is not clear. We took advantage of lineage-tracing experiments combined with 3D visualizations and gene knockout strategies to address this long-standing question. We revealed that Schwann cell precursors are recruited from the local innervation during embryonic development and give rise to extracutaneous melanocytes in the heart, brain meninges, inner ear, and other locations. In embryos with a knockout of the EdnrB receptor, a condition imitating Waardenburg syndrome, we observed only nerve-associated melanoblasts, which failed to detach from the nerves and to enter the inner ear. Finally, we looked into the evolutionary aspects of extracutaneous melanocytes and found that pigment cells are associated mainly with nerves and blood vessels in amphibians and fish. This new knowledge of the nerve-dependent origin of extracutaneous pigment cells might be directly relevant to the formation of extracutaneous melanoma in humans.

Schwann cell precursors generate sympathoadrenal system during zebrafish development

2021 ◽  
Author(s):  
Dmitrii Kamenev ◽  
Kazunori Sunadome ◽  
Maxim Shirokov ◽  
Andrey S. Chagin ◽  
Ajeet Singh ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Sympathoadrenal System ◽  
Zebrafish Development ◽  
Schwann Cell Precursors

Schwann cell precursors and their development

Glia ◽  
1991 ◽  
Vol 4 (2) ◽  
pp. 185-194 ◽  
Author(s):  
Kristjan R. Jessen ◽  
Rhona Mirsky
Keyword(s):  
Schwann Cell ◽  
Schwann Cell Precursors

scholarly journals EPHB6 and testosterone in concert regulate epinephrine release by adrenal gland chromaffin cells

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Yujia Wang ◽  
Wei Shi ◽  
Alexandre Blanchette ◽  
Junzheng Peng ◽  
Shijie Qi ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Chromaffin Cells

scholarly journals EPHB6 controls catecholamine biosynthesis by up-regulating tyrosine hydroxylase transcription in adrenal gland chromaffin cells

2019 ◽  
Vol 294 (17) ◽  
pp. 6871-6887 ◽  
Author(s):  
Wei Shi ◽  
Yujia Wang ◽  
Junzheng Peng ◽  
Shijie Qi ◽  
Nicolas Vitale ◽  
...  
Keyword(s):  
Tyrosine Hydroxylase ◽  
Adrenal Gland ◽  
Chromaffin Cells ◽  
Catecholamine Biosynthesis
Sign in / Sign up

Export Citation Format

Share Document