Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicity

F Rizvi; S Shukla; P Kakkar

doi:10.1038/cddis.2014.118

Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicity

Cell Death and Disease ◽

10.1038/cddis.2014.118 ◽

2014 ◽

Vol 5 (3) ◽

pp. e1153-e1153 ◽

Cited By ~ 34

Author(s):

F Rizvi ◽

S Shukla ◽

P Kakkar

Keyword(s):

Protein Phosphatase ◽

Essential Role ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Repeat Protein ◽

Fyn Kinase ◽

Protein Phosphatase 2 ◽

Leucine Rich Repeat Protein

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PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2)

Atlas of Genetics and Cytogenetics in Oncology and Haematology ◽

10.4267/2042/44756 ◽

2011 ◽

Author(s):

AK O'Neill ◽

AC Newton

Keyword(s):

Protein Phosphatase ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Repeat Protein ◽

Protein Phosphatase 2 ◽

Leucine Rich Repeat Protein

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MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2

Journal of Experimental & Clinical Cancer Research ◽

10.1186/s13046-017-0516-2 ◽

2017 ◽

Vol 36 (1) ◽

Cited By ~ 30

Author(s):

Lei Ding ◽

Shanyong Zhang ◽

Mu Xu ◽

Renwen Zhang ◽

Pengcheng Sui ◽

...

Keyword(s):

Gastric Cancer ◽

Cancer Cells ◽

Protein Phosphatase ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Gastric Cancer Cells ◽

Repeat Protein ◽

Protein Phosphatase 2 ◽

Leucine Rich Repeat Protein ◽

Malignant Behavior

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PH Domain Leucine-Rich Repeat Protein Phosphatase (PHLPP)

Encyclopedia of Signaling Molecules ◽

10.1007/978-1-4614-6438-9_101823-1 ◽

2016 ◽

pp. 1-7

Author(s):

Agnieszka T. Grzechnik ◽

Alexandra C. Newton

Keyword(s):

Protein Phosphatase ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Repeat Protein ◽

Leucine Rich Repeat Protein

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Diacylglycerol Kinase δ Modulates Akt Phosphorylation through Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase 2 (PHLPP2)

Journal of Biological Chemistry ◽

10.1074/jbc.m112.407379 ◽

2012 ◽

Vol 288 (3) ◽

pp. 1439-1447 ◽

Cited By ~ 16

Author(s):

Tracy M. Crotty ◽

Tomoyuki Nakano ◽

Diana M. Stafforini ◽

Matthew K. Topham

Keyword(s):

Protein Phosphatase ◽

Diacylglycerol Kinase ◽

Pleckstrin Homology Domain ◽

Leucine Rich Repeat ◽

Pleckstrin Homology ◽

Repeat Protein ◽

Akt Phosphorylation ◽

Protein Phosphatase 2 ◽

Leucine Rich Repeat Protein

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PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum

Cell Death and Differentiation ◽

10.1038/cdd.2009.127 ◽

2009 ◽

Vol 17 (2) ◽

pp. 324-335 ◽

Cited By ~ 32

Author(s):

A Saavedra ◽

J M García-Martínez ◽

X Xifró ◽

A Giralt ◽

J F Torres-Peraza ◽

...

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Protein Phosphatase ◽

Protein Phosphatase 1 ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Repeat Protein ◽

Survival Pathway ◽

Leucine Rich Repeat Protein

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Discovery of Small Molecule Inhibitors of the PH Domain Leucine-Rich Repeat Protein Phosphatase (PHLPP) by Chemical and Virtual Screening

Journal of Medicinal Chemistry ◽

10.1021/jm100331d ◽

2010 ◽

Vol 53 (19) ◽

pp. 6899-6911 ◽

Cited By ~ 49

Author(s):

Emma Sierecki ◽

William Sinko ◽

J. Andrew McCammon ◽

Alexandra C. Newton

Keyword(s):

Virtual Screening ◽

Small Molecule ◽

Protein Phosphatase ◽

Small Molecule Inhibitors ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Repeat Protein ◽

Leucine Rich Repeat Protein

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Deletion of the PH-domain and Leucine-rich Repeat Protein Phosphatase 1 (Phlpp1) Increases Fibroblast Growth Factor (Fgf) 18 Expression and Promotes Chondrocyte Proliferation

Journal of Biological Chemistry ◽

10.1074/jbc.m114.612937 ◽

2015 ◽

Vol 290 (26) ◽

pp. 16272-16280 ◽

Cited By ~ 23

Author(s):

Elizabeth W. Bradley ◽

Lomeli R. Carpio ◽

Alexandra C. Newton ◽

Jennifer J. Westendorf

Keyword(s):

Growth Factor ◽

Fibroblast Growth Factor ◽

Protein Phosphatase ◽

Protein Phosphatase 1 ◽

Fibroblast Growth ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Chondrocyte Proliferation ◽

Repeat Protein ◽

Leucine Rich Repeat Protein

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MicroRNA-331-3p promotes proliferation and metastasis of hepatocellular carcinoma by targeting PH domain and leucine-rich repeat protein phosphatase

Hepatology ◽

10.1002/hep.27221 ◽

2014 ◽

Vol 60 (4) ◽

pp. 1251-1263 ◽

Cited By ~ 101

Author(s):

Rui-Min Chang ◽

Hao Yang ◽

Feng Fang ◽

Jiang-Feng Xu ◽

Lian-Yue Yang

Keyword(s):

Hepatocellular Carcinoma ◽

Protein Phosphatase ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Repeat Protein ◽

Proliferation And Metastasis ◽

Leucine Rich Repeat Protein

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Expression of PH Domain Leucine-rich Repeat Protein Phosphatase, Forkhead Homeobox Type O 3a and RAD51, and their Relationships with Clinicopathologic Features and Prognosis in Ovarian Serous Adenocarcinoma

Chinese Medical Journal ◽

10.4103/0366-6999.198932 ◽

2017 ◽

Vol 130 (3) ◽

pp. 280-287 ◽

Cited By ~ 1

Author(s):

Jun Zhang ◽

Jun-Chao Wang ◽

Yue-Hong Li ◽

Rui-Xue Wang ◽

Xiao-Mei Fan

Keyword(s):

Protein Phosphatase ◽

Clinicopathologic Features ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Serous Adenocarcinoma ◽

Repeat Protein ◽

Ovarian Serous Adenocarcinoma ◽

Leucine Rich Repeat Protein

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Regulation Of Neutrophil Adhesion And Migration By PH Domain And Leucine Rich Repeat Protein Phosphatase

10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1380 ◽

2012 ◽

Author(s):

Xiangdong Zhu ◽

Jonathan Learoyd ◽

Lee Tang ◽

Linda Ning ◽

Zuo-Hui Shao ◽

...

Keyword(s):

Protein Phosphatase ◽

Neutrophil Adhesion ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Repeat Protein ◽

And Migration ◽

Leucine Rich Repeat Protein

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