scholarly journals Low bone mineral density is associated with insulin resistance in bone marrow transplant subjects

2009 ◽  
Vol 43 (12) ◽  
pp. 953-957 ◽  
Author(s):  
G A M Faulhaber ◽  
M O Premaor ◽  
H L Moser Filho ◽  
L M Silla ◽  
T W Furlanetto
Keyword(s):  
Bone Mineral Density ◽  
Insulin Resistance ◽  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Bone Mineral ◽  
Marrow Transplant ◽  
Mineral Density ◽  
Low Bone Mineral Density

scholarly journals Bone Mineral Density in Congenital Generalized Lipodystrophy: The Role of Bone Marrow Tissue, Adipokines, and Insulin Resistance

2021 ◽  
Vol 18 (18) ◽  
pp. 9724
Author(s):  
Erika Bastos Lima Freire ◽  
Catarina Brasil d’Alva ◽  
Mayara Ponte Madeira ◽  
Grayce Ellen da Cruz Paiva Lima ◽  
Ana Paula Dias Rangel Montenegro ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Insulin Resistance ◽  
Bone Marrow ◽  
Adipose Tissue ◽  
Bone Mineral ◽  
Mineral Density ◽  
Alcoholic Fatty Liver ◽  
Bone Marrow Tissue ◽  
Congenital Generalized Lipodystrophy

Congenital Generalized Lipodystrophy (CGL) is a rare syndrome characterized by the almost total absence of subcutaneous adipose tissue due to the inability of storing lipid in adipocytes. Patients present generalized lack of subcutaneous fat and normal to low weight. They evolve with severe metabolic disorders, non-alcoholic fatty liver disease, early cardiac abnormalities, and infectious complications. Although low body weight is a known risk factor for osteoporosis, it has been reported that type 1 and 2 CGL have a tendency of high bone mineral density (BMD). In this review, we discuss the role of bone marrow tissue, adipokines, and insulin resistance in the setting of the normal to high BMD of CGL patients. Data bases from Pubmed and LILACS were searched, and 113 articles published until 10 April 2021 were obtained. Of these, 76 were excluded for not covering the review topic. A manual search for additional literature was performed using the bibliographies of the studies located. The elucidation of the mechanisms responsible for the increase in BMD in this unique model of insulin resistance may contribute to the understanding of the interrelationships between bone, muscle, and adipose tissue in a pathophysiological and therapeutic perspective.

Evaluation with densitometry of patients with breast cancer and low bone mineral density after 2 years of treatment

2013 ◽  
Author(s):  
Sonia Munoz Gil ◽  
Tomas Mut Dolera ◽  
Belen C Garrido Lopez ◽  
M D Torregrosa Maicas ◽  
R Girones Sarrio ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Low Bone Mineral Density
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