Low bone mineral density is associated with high serum ferritin levels and insulin resistance in post bone marrow transplant subjects

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S413
Author(s):  
M.O. Premaor ◽  
G. Faulhauber ◽  
H. Moser ◽  
L. Silla ◽  
T. Furlanetto
Keyword(s):  
Bone Mineral Density ◽  
Insulin Resistance ◽  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Bone Mineral ◽  
Serum Ferritin ◽  
Marrow Transplant ◽  
High Serum ◽  
Mineral Density ◽  
Low Bone Mineral Density

scholarly journals Low bone mineral density is associated with insulin resistance in bone marrow transplant subjects

2009 ◽  
Vol 43 (12) ◽  
pp. 953-957 ◽  
Author(s):  
G A M Faulhaber ◽  
M O Premaor ◽  
H L Moser Filho ◽  
L M Silla ◽  
T W Furlanetto
Keyword(s):  
Bone Mineral Density ◽  
Insulin Resistance ◽  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Bone Mineral ◽  
Marrow Transplant ◽  
Mineral Density ◽  
Low Bone Mineral Density

scholarly journals High serum FSH is not a risk factor for low bone mineral density in infertile men

Bone ◽  
2020 ◽  
Vol 136 ◽  
pp. 115366
Author(s):  
Leen Antonio ◽  
Lærke Priskorn ◽  
Inge A. Olesen ◽  
Jørgen H. Petersen ◽  
Dirk Vanderschueren ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Risk Factor ◽  
Bone Mineral ◽  
High Serum ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Infertile Men

Association Between Serum Ferritin Levels and Low Bone Mineral Density in Postmenopausal Osteoporosis Women

2020 ◽  
Author(s):  
Lama ALjeshi ◽  
Shaden Haddad
Keyword(s):  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Postmenopausal Osteoporosis ◽  
Bone Mineral ◽  
Serum Ferritin ◽  
Serum Ferritin Level ◽  
Ferritin Level ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Femur Neck

As women go through menopause, serum estrogen decreases, and ferritin increases. Ferritin is an essential component of the body, but many studies have stated that ferritin, which exceeds the normal physiological range, may potentially cause health problems in women. The aim of this study is to investigate the relationship between bone mineral density and serum ferritin levels in post-menopausal women and to evaluate serum ferritin levels as a potential biomarker for postmenopausal osteoporosis. Serum ferritin levels were measured in 62 postmenopausal women with low bone mineral density, and in 18 postmenopausal healthy control women using a standardized Enzyme-Linked Immune Sorbent Assay (ELISA) kit. Bone mineral density BMD was assessed at the lumbar spine and femoral neck. The mean serum ferritin level was significantly higher in the postmenopausal women with low BMD group (group 1) than in the normal control group (group 2), respectively (mean=262.69 vs. 181.44 ng/ml, (P<0.05), and serum ferritin level was negatively correlated with BMD among low BMD postmenopausal women's group (R= -0.628, P=0.0001), and in the healthy postmenopausal group (R= -0.052, P=0.838). A comparison of the BMD between spine and femur neck sites shows that the frequency of low BMD in the spine site is higher than the femur neck site. Our findings show that increased serum ferritin levels were associated with low bone mineral density in postmenopausal osteoporosis.

High Serum Retinol as a Relevant Contributor to Low Bone Mineral Density in Postmenopausal Osteoporotic Women

2018 ◽  
Vol 102 (6) ◽  
pp. 651-656 ◽  
Author(s):  
Cristina Navarro-Valverde ◽  
Javier Caballero-Villarraso ◽  
José M. Mata-Granados ◽  
Antonio Casado-Díaz ◽  
Manuel Sosa-Henríquez ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
High Serum ◽  
Serum Retinol ◽  
Mineral Density ◽  
Low Bone Mineral Density

High serum FSH is not a risk factor for low bone mineral density in infertile men

2020 ◽  
Author(s):  
Leen Antonio ◽  
Lærke Priskorn ◽  
Inge A Olesen ◽  
Dirk Vanderschueren ◽  
Niels Joergensen
Keyword(s):  
Bone Mineral Density ◽  
Risk Factor ◽  
Bone Mineral ◽  
High Serum ◽  
Mineral Density ◽  
Low Bone Mineral Density ◽  
Infertile Men

scholarly journals Bone Mineral Density in Congenital Generalized Lipodystrophy: The Role of Bone Marrow Tissue, Adipokines, and Insulin Resistance

2021 ◽  
Vol 18 (18) ◽  
pp. 9724
Author(s):  
Erika Bastos Lima Freire ◽  
Catarina Brasil d’Alva ◽  
Mayara Ponte Madeira ◽  
Grayce Ellen da Cruz Paiva Lima ◽  
Ana Paula Dias Rangel Montenegro ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Insulin Resistance ◽  
Bone Marrow ◽  
Adipose Tissue ◽  
Bone Mineral ◽  
Mineral Density ◽  
Alcoholic Fatty Liver ◽  
Bone Marrow Tissue ◽  
Congenital Generalized Lipodystrophy

Congenital Generalized Lipodystrophy (CGL) is a rare syndrome characterized by the almost total absence of subcutaneous adipose tissue due to the inability of storing lipid in adipocytes. Patients present generalized lack of subcutaneous fat and normal to low weight. They evolve with severe metabolic disorders, non-alcoholic fatty liver disease, early cardiac abnormalities, and infectious complications. Although low body weight is a known risk factor for osteoporosis, it has been reported that type 1 and 2 CGL have a tendency of high bone mineral density (BMD). In this review, we discuss the role of bone marrow tissue, adipokines, and insulin resistance in the setting of the normal to high BMD of CGL patients. Data bases from Pubmed and LILACS were searched, and 113 articles published until 10 April 2021 were obtained. Of these, 76 were excluded for not covering the review topic. A manual search for additional literature was performed using the bibliographies of the studies located. The elucidation of the mechanisms responsible for the increase in BMD in this unique model of insulin resistance may contribute to the understanding of the interrelationships between bone, muscle, and adipose tissue in a pathophysiological and therapeutic perspective.

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