scholarly journals Influence of eicosapentaenoic acid supplementation on lean body mass in cancer cachexia

2011 ◽  
Vol 105 (10) ◽  
pp. 1469-1473 ◽  
Author(s):  
R A Murphy ◽  
E Yeung ◽  
V C Mazurak ◽  
M Mourtzakis
Keyword(s):  
Eicosapentaenoic Acid ◽  
Lean Body Mass ◽  
Body Mass ◽  
Cancer Cachexia ◽  
Acid Supplementation

scholarly journals Baseline deficiency of the anti-inflammatory eicosapentaenoic acid in cell membranes worsens lean body mass wasting induced by inactivity

2017 ◽  
Vol 14 ◽  
pp. 36-41 ◽  
Author(s):  
Filippo Giorgio Di Girolamo ◽  
Francesco Agostini ◽  
Sara Mazzucco ◽  
Roberta Situlin ◽  
Filippo Mearelli ◽  
...  
Keyword(s):  
Eicosapentaenoic Acid ◽  
Lean Body Mass ◽  
Body Mass ◽  
Cell Membranes ◽  
Mass Wasting ◽  
Anti Inflammatory

scholarly journals Conjugated Linoleic Acid Supplementation for Twelve Weeks Increases Lean Body Mass in Obese Humans

2007 ◽  
Vol 137 (5) ◽  
pp. 1188-1193 ◽  
Author(s):  
Susan E. Steck ◽  
Allison M. Chalecki ◽  
Paul Miller ◽  
Jason Conway ◽  
Gregory L. Austin ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Lean Body Mass ◽  
Body Mass ◽  
Acid Supplementation

scholarly journals Ghrelin Treatment Causes Increased Food Intake and Retention of Lean Body Mass in a Rat Model of Cancer Cachexia

Endocrinology ◽  
2007 ◽  
Vol 148 (6) ◽  
pp. 3004-3012 ◽  
Author(s):  
Mark D. DeBoer ◽  
Xin Xia Zhu ◽  
Peter Levasseur ◽  
Michael M. Meguid ◽  
Susumu Suzuki ◽  
...  
Keyword(s):  
Food Intake ◽  
Lean Body Mass ◽  
Body Mass ◽  
Rat Model ◽  
Cancer Cachexia

scholarly journals Pancreatic Cancer Cachexia: The Role of Nutritional Interventions

Healthcare ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. 89 ◽  
Author(s):  
Toni Mitchell ◽  
Lewis Clarke ◽  
Alexandra Goldberg ◽  
Karen S. Bishop
Keyword(s):  
Quality Of Life ◽  
Pancreatic Cancer ◽  
Lean Body Mass ◽  
Body Mass ◽  
Nutritional Support ◽  
Cancer Cachexia ◽  
Calorie Intake ◽  
Nutritional Interventions ◽  
Oral Nutritional Supplements

Pancreatic cancer is a cancer with one of the highest mortality rates and many pancreatic cancer patients present with cachexia at diagnosis. The definition of cancer cachexia is not consistently applied in the clinic or across studies. In general, it is “defined as a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass with or without loss of fat mass that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment.” Many regard cancer cachexia as being resistant to dietary interventions. Cachexia is associated with a negative impact on survival and quality of life. In this article, we outline some of the mechanisms of pancreatic cancer cachexia and discuss nutritional interventions to support the management of pancreatic cancer cachexia. Cachexia is driven by a combination of reduced appetite leading to reduced calorie intake, increased metabolism, and systemic inflammation driven by a combination of host cytokines and tumour derived factors. The ketogenic diet showed promising results, but these are yet to be confirmed in human clinical trials over the long-term. L-carnitine supplementation showed improved quality of life and an increase in lean body mass. As a first step towards preventing and managing pancreatic cancer cachexia, nutritional support should be provided through counselling and the provision of oral nutritional supplements to prevent and minimise loss of lean body mass.

scholarly journals Effects of perioperative Eicosapentaenoic acid-enriched oral nutritional supplement on lean body mass after total gastrectomy for gastric cancer

2019 ◽  
Vol 10 (5) ◽  
pp. 1070-1076 ◽  
Author(s):  
Toru Aoyama ◽  
Takaki Yoshikawa ◽  
Satoshi Ida ◽  
Haruhiko Cho ◽  
Kentaro Sakamaki ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Eicosapentaenoic Acid ◽  
Total Gastrectomy ◽  
Lean Body Mass ◽  
Body Mass ◽  
Nutritional Supplement ◽  
Oral Nutritional Supplement
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