scholarly journals Comparison of MIB-1 proliferation index with S-phase fraction in human breast carcinomas

1996 ◽  
Vol 73 (5) ◽  
pp. 640-643 ◽  
Author(s):  
PA Ellis ◽  
A Makris ◽  
SA Burton ◽  
J Titley ◽  
MG Ormerod ◽  
...  
Keyword(s):  
S Phase ◽  
Phase Fraction ◽  
Proliferation Index ◽  
Breast Carcinomas ◽  
Human Breast ◽  
Human Breast Carcinomas ◽  
Mib 1

Ki67 Index and S-Phase Fraction in Human Breast Carcinomas: Comparison and Correlations with Prognostic Factors

1990 ◽  
Vol 94 (6) ◽  
pp. 681-686 ◽  
Author(s):  
Philippe Vielh ◽  
Sylvie Chevillard ◽  
Veronique Mosseri ◽  
Bruno Donatini ◽  
Henri Magdelenat
Keyword(s):  
Prognostic Factors ◽  
S Phase ◽  
Phase Fraction ◽  
Ki67 Index ◽  
Breast Carcinomas ◽  
Human Breast ◽  
Human Breast Carcinomas

Evidence for a second tumor suppressor gene on 17p linked to high S-phase index in primary human breast carcinomas

1994 ◽  
Vol 76 (2) ◽  
pp. 106-111 ◽  
Author(s):  
Giorgio R. Merlo ◽  
Tiziana Venesio ◽  
Amelia Bernardi ◽  
Craig S. Cropp ◽  
Francesca Diella ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
S Phase ◽  
Breast Carcinomas ◽  
Human Breast ◽  
Phase Index ◽  
Human Breast Carcinomas ◽  
Primary Human Breast ◽  
Second Tumor

scholarly journals Intratumoral Variations in DNA Ploidy and S-Phase Fraction in Human Breast Cancer

2001 ◽  
Vol 23 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Conny Arnerlöv ◽  
Stefan O. Emdin ◽  
Stefan Cajander ◽  
Nils‐Olof Bengtsson ◽  
Björn Tavelin ◽  
...  
Keyword(s):  
Human Breast Cancer ◽  
Dna Ploidy ◽  
S Phase ◽  
Phase Fraction ◽  
Prognostic Indicators ◽  
Intratumor Heterogeneity ◽  
Breast Carcinomas ◽  
Human Breast ◽  
Dna Index ◽  
Aneuploidy Rate

To study intratumoral DNA ploidy heterogeneity and S‐phase fraction (SPF) variability, we prospectively collected five different samples from 48 breast carcinomas and each sample was analysed separately by flow cytometry. Aneuploidy rate was 89.6% after analysis of four or five samples. DNA ploidy heterogeneity, i.e., different samples classified as either DNA euploid or DNA aneuploid in the same tumor was seen in 17%, and DNA index heterogeneity, i.e., tumor populations with different DNA indices (DIs) seen in different samples was 44%. A statistical model defining SPF heterogeneity is proposed. SPF heterogeneity as defined by us was 71%, and as expected the SPF heterogeneity rate increased significantly with increasing number of analysed samples. Four or more samples are needed to detect the most deviant (highest) SPF values. An unrecognized intratumor heterogeneity of DNA ploidy and SPF may partly explain the conflicting results reported in the literature on the above prognostic indicators.

In primary human breast carcinomas mutations in exons 5 and 6 of the p53 gene are associated with a high s-phase index

1993 ◽  
Vol 54 (4) ◽  
pp. 531-535 ◽  
Author(s):  
Giorgio R. Merlo ◽  
Amelia Bernardi ◽  
Francesca Diella ◽  
Tiziana Venesio ◽  
Alberto P. M. Cappa ◽  
...  
Keyword(s):  
P53 Gene ◽  
S Phase ◽  
Breast Carcinomas ◽  
Human Breast ◽  
Phase Index ◽  
Human Breast Carcinomas ◽  
Primary Human Breast

scholarly journals BUB1infrequently mutated in human breast carcinomas

2003 ◽  
Vol 22 (5) ◽  
pp. 420-420 ◽  
Author(s):  
Anita Langerød ◽  
Maria Strømberg ◽  
Koei Chin ◽  
Vessela N. Kristensen ◽  
Anne-Lise Børresen-Dale
Keyword(s):  
Breast Carcinomas ◽  
Human Breast ◽  
Human Breast Carcinomas

scholarly journals Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas

Oncogene ◽  
2004 ◽  
Vol 23 (36) ◽  
pp. 6047-6055 ◽  
Author(s):  
Vassiliki Theodorou ◽  
Mandy Boer ◽  
Britta Weigelt ◽  
Jos Jonkers ◽  
Martin van der Valk ◽  
...  
Keyword(s):  
Insertional Mutagenesis ◽  
Mammary Tumors ◽  
Breast Carcinomas ◽  
Human Breast ◽  
Human Breast Carcinomas ◽  
Mouse Mammary Tumors
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