scholarly journals Tug of war in the haematopoietic stem cell niche: do myeloma plasma cells compete for the HSC niche?

2012 ◽  
Vol 2 (9) ◽  
pp. e91-e91 ◽  
Author(s):  
J E Noll ◽  
S A Williams ◽  
L E Purton ◽  
A C W Zannettino
Keyword(s):  
Stem Cell ◽  
Stem Cell Niche ◽  
Plasma Cells ◽  
Haematopoietic Stem Cell ◽  
Hsc Niche ◽  
Cell Niche

scholarly journals The Haematopoietic Stem Cell Niche: New Insights into the Mechanisms Regulating Haematopoietic Stem Cell Behaviour

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Andrew J. Lilly ◽  
William E. Johnson ◽  
Christopher M. Bunce
Keyword(s):  
Bone Marrow ◽  
Stem Cell ◽  
Stem Cell Niche ◽  
Cell Types ◽  
Haematopoietic Stem Cell ◽  
Cell Behaviour ◽  
Ongoing Research ◽  
Hsc Niche ◽  
Numerous Cell ◽  
Cell Niche

The concept of the haematopoietic stem cell (HSC) niche was formulated by Schofield in the 1970s, as a region within the bone marrow containing functional cell types that can maintain HSC potency throughout life. Since then, ongoing research has identified numerous cell types and a plethora of signals that not only maintain HSCs, but also dictate their behaviour with respect to homeostatic requirements and exogenous stresses. It has been proposed that there are endosteal and vascular niches within the bone marrow, which are thought to regulate different HSC populations. However, recent data depicts a more complicated picture, with functional crosstalk between cells in these two regions. In this review, recent research into the endosteal/vascular cell types and signals regulating HSC behaviour are considered, together with the possibility of a single subcompartmentalised niche.

scholarly journals The bone metastasis niche in breast cancer: potential overlap with the haematopoietic stem cell niche in vivo

2019 ◽  
Vol 17 ◽  
pp. 100244 ◽  
Author(s):  
Gloria Allocca ◽  
Russell Hughes ◽  
Ning Wang ◽  
Hannah K Brown ◽  
Penelope D Ottewell ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Stem Cell ◽  
Bone Metastasis ◽  
Stem Cell Niche ◽  
Haematopoietic Stem Cell ◽  
Cell Niche

scholarly journals The haematopoietic stem cell niche at a glance

2011 ◽  
Vol 124 (21) ◽  
pp. 3529-3535 ◽  
Author(s):  
C. Lo Celso ◽  
D. T. Scadden
Keyword(s):  
Stem Cell ◽  
Stem Cell Niche ◽  
Haematopoietic Stem Cell ◽  
Cell Niche

scholarly journals Osteoblastic cells regulate the haematopoietic stem cell niche

Nature ◽  
2003 ◽  
Vol 425 (6960) ◽  
pp. 841-846 ◽  
Author(s):  
L. M. Calvi ◽  
G. B. Adams ◽  
K. W. Weibrecht ◽  
J. M. Weber ◽  
D. P. Olson ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Niche ◽  
Haematopoietic Stem Cell ◽  
Osteoblastic Cells ◽  
Cell Niche

scholarly journals Gata3 targets Runx1 in the embryonic haematopoietic stem cell niche

IUBMB Life ◽  
2019 ◽  
Vol 72 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Simon R. Fitch ◽  
Chrysa Kapeni ◽  
Aikaterini Tsitsopoulou ◽  
Nicola K. Wilson ◽  
Berthold Göttgens ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Niche ◽  
Haematopoietic Stem Cell ◽  
Cell Niche

scholarly journals In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

Nature ◽  
2011 ◽  
Vol 474 (7350) ◽  
pp. 216-219 ◽  
Author(s):  
Joji Fujisaki ◽  
Juwell Wu ◽  
Alicia L. Carlson ◽  
Lev Silberstein ◽  
Prabhakar Putheti ◽  
...  
Keyword(s):  
Stem Cell ◽  
In Vivo Imaging ◽  
Stem Cell Niche ◽  
Treg Cells ◽  
Immune Privilege ◽  
Haematopoietic Stem Cell ◽  
Cell Niche

Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms

Nature ◽  
2014 ◽  
Vol 512 (7512) ◽  
pp. 78-81 ◽  
Author(s):  
Lorena Arranz ◽  
Abel Sánchez-Aguilera ◽  
Daniel Martín-Pérez ◽  
Joan Isern ◽  
Xavier Langa ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Niche ◽  
Myeloproliferative Neoplasms ◽  
Haematopoietic Stem Cell ◽  
Cell Niche
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