scholarly journals Association of Prothrombotic Status With Markers of Cerebral Small Vessel Disease in Elderly Hypertensive Patients

2012 ◽  
Vol 25 (10) ◽  
pp. 1088-1094 ◽  
Author(s):  
Michiaki Nagai ◽  
Satoshi Hoshide ◽  
Kazuomi Kario
Keyword(s):  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Hypertensive Patients ◽  
Vessel Disease ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

scholarly journals Cerebral Small Vessel Disease Associated with Subclinical Vascular Damage Indicators in Asymptomatic Hypertensive Patients

2019 ◽  
Vol 9 (9) ◽  
pp. 91
Author(s):  
Zenaida Milagros Hernández-Díaz ◽  
Marisol Peña-Sánchez ◽  
Alina González-Quevedo Monteagudo ◽  
Sergio González-García ◽  
Paula Andrea Arias-Cadena ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Vascular Damage ◽  
Small Vessel ◽  
Hypertensive Retinopathy ◽  
Hypertensive Patients ◽  
Lacunar Infarcts ◽  
Vessel Disease ◽  
Subclinical Vascular Damage

Background: Cerebral small vessel disease (CSVD) is frequent in patients with cardiovascular risk factors including arterial hypertension, and it is associated with vascular damage in other organs and the risk of stroke, cognitive impairment, and dementia. Early diagnosis of CSVD could prevent deleterious consequences. Objective: To characterize CSVD associated with indicators of subclinical vascular damage in asymptomatic hypertensive patients. Materials and Methods: Participants were hypertensive (HT) and non-hypertensive (non-HT) individuals; without signs of cerebrovascular disease, dementia, and chronic renal failure. For CSVD, white matter hyperintensities (WMH), enlarged Virchow–Robin perivascular spaces (EVRPS), lacunar infarcts, and microbleeds were investigated. Subclinical vascular damage was evaluated (hypertensive retinopathy, microalbuminuria, and extracranial carotid morphology: intima media thickness (IMT) and atheroma plaque). Results: CSVD MRI findings were more frequent in HT; as well as greater intimal thickening. The IMT + plaque was significantly associated with all MRI variables; but retinopathy was correlated with EVRPS and lacunar infarcts. Only microalbuminuria was related to the greater severity of WMH in HT. Multivariate analysis evidenced that CSVD was independently associated with the combination of indicators of vascular damage and systolic blood pressure. Conclusions: Combining indicators of subclinical vascular damage, such as carotid morphological variables, microalbuminuria, and hypertensive retinopathy for early detection of CSVD in asymptomatic hypertensive patients could prove to be useful to take actions for the prevention of irreversible brain damage, which could lead to cognitive impairment, dementia and stroke.

scholarly journals Increased risk of cognitive impairment and more severe brain lesions in hypertensive compared to non-hypertensive patients with cerebral small vessel disease

2018 ◽  
Vol 20 (9) ◽  
pp. 1260-1265 ◽  
Author(s):  
Aleksandra M. Pavlovic ◽  
Tatjana Pekmezovic ◽  
Jasna Zidverc Trajkovic ◽  
Gordana Tomic ◽  
Edita Cvitan ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Brain Lesions ◽  
Small Vessel ◽  
Hypertensive Patients ◽  
Vessel Disease ◽  
Increased Risk

scholarly journals Increased Aortic Pulse Wave Velocity Is Associated With Silent Cerebral Small-Vessel Disease in Hypertensive Patients

Hypertension ◽  
2008 ◽  
Vol 52 (6) ◽  
pp. 1120-1126 ◽  
Author(s):  
Léon H.G. Henskens ◽  
Abraham A. Kroon ◽  
Robert J. van Oostenbrugge ◽  
Ed H.B.M. Gronenschild ◽  
Monique M.J.J. Fuss-Lejeune ◽  
...  
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Small Vessel Disease ◽  
Aortic Pulse Wave Velocity ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Hypertensive Patients ◽  
Vessel Disease

scholarly journals Relationship between cerebral blood flow and later cognitive decline in hypertensive patients with cerebral small vessel disease

2009 ◽  
Vol 32 (9) ◽  
pp. 816-820 ◽  
Author(s):  
Kazuo Kitagawa ◽  
Naohiko Oku ◽  
Yasuyuku Kimura ◽  
Yoshiki Yagita ◽  
Manabu Sakaguchi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Cognitive Decline ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Hypertensive Patients ◽  
Vessel Disease

Neuroimaging of Cerebral Small Vessel Disease and Retinopathy in Hypertensive Patients

2018 ◽  
Vol 24 (9) ◽  
pp. 6753-6755
Author(s):  
Yetty Ramli ◽  
Mellia Ambarningrum ◽  
Eva Dewati ◽  
Jacub Pendelaki
Keyword(s):  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Hypertensive Patients ◽  
Vessel Disease
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