Endoscopic Placement of a U-Shaped Plastic Stent in Patients With Recurrent Acute Pancreatitis and Incomplete Pancreas Divisum

2017 ◽  
Vol 112 (12) ◽  
pp. 1777
Author(s):  
Qi-Shan Zeng ◽  
Chun-Cheng Wu ◽  
Wei Liu ◽  
Lian-Song Ye ◽  
Shan Jiang ◽  
...  
2021 ◽  
Vol 09 (07) ◽  
pp. E1164-E1170
Author(s):  
David M. de Jong ◽  
Pauline M. Stassen ◽  
Jan Werner Poley ◽  
Paul Fockens ◽  
Robin Timmer ◽  
...  

Abstract Background and study aims Although the majority of patients with pancreas divisum (PDiv) are asymptomatic, a subgroup present with recurrent pancreatitis or pain for which endoscopic therapy may be indicated. The aim of this study was to evaluate success rates and long-term outcomes of endoscopic treatment in patients with symptomatic PDiv. Patients and methods A multicenter, retrospective cohort study was performed. Patients with symptomatic PDiv presenting with recurrent acute pancreatitis (RAP), chronic pancreatitis (CP), or chronic abdominal pancreatic-type pain (CAP) who underwent endoscopic retrograde cholangiopancreatography (ERCP) between January 2000 and December 2019 were included. The primary outcome was clinical success, defined as either no recurrent episode of acute pancreatitis (AP) for RAP patients, no flares for CP patients, or absence of abdominal pain for patients with CAP after technically successful ERCP. Results In 60 of 81 patients (74.1 %) a technically successful papilla minor intervention was performed. Adverse events were reported in 30 patients (37 %), with post-ERCP pancreatitis in 18 patients. The clinical success rate for patients with at least 3 months of follow-up was 42.6 %, with higher rates of success among patients presenting with RAP (44.4 %) as compared to those with CP (33.3 %) or CAP (33.3 %). Long-term sustained response was present in 40.9 % of patients with a technically successful intervention. In patients with RAP who did not completely respond to treatment, the mean number of AP episodes after treatment decreased significantly from 3.5 to 1.1 per year, and subsequently the interval between AP episodes increased from 278 to 690 days (P = 0.0006). A potential predictive factor of failure of clinical success after technically successful ERCP, at univariate analysis, was male sex (OR = 0.25, P = 0.02). Conclusions Endoscopic therapy in patients with symptomatic PDiv is moderately effective, with its highest yield in patients presenting with RAP. Future studies are needed to assess factors predictive for success of endoscopic therapy and potential risk factors for relapse after ERCP.


2016 ◽  
Vol 83 (5) ◽  
pp. AB275-AB276 ◽  
Author(s):  
Zachary A. Zator ◽  
Rohit Das ◽  
Rawad Mounzer ◽  
Arun Mannem ◽  
Dhiraj Yadav ◽  
...  

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S47
Author(s):  
Mohsin Aslam ◽  
Steffie Avanthi ◽  
Govardhan Balle ◽  
V. Vishnubhotla Ravikanth ◽  
Zaheer Nabi ◽  
...  

HPB Surgery ◽  
1994 ◽  
Vol 7 (3) ◽  
pp. 231-235 ◽  
Author(s):  
J. Kollias ◽  
J. Toouli

Duodenal malformations are the third commonest cause of intestinal obstruction in infants1. A spectrum of intrinsic obstructive lesions within the duodenum ranges from atresia to congenital bands2. Rarely, duodenal malformations may first present in adulthood. Less than 70 cases of duodenal web presenting in an adult have been reported in the literature. In 10 patients the presentation was associated with pancreatitis. We report a case of congenital duodenal web associated with pancreas divisum which first presented in an adult with the clinical characteristics of recurrent acute pancreatitis.


2021 ◽  
Vol 49 (11) ◽  
pp. 030006052110601
Author(s):  
Kunyi Liu ◽  
Xuechen Liu ◽  
Chengyi Shi ◽  
Siqi Liu ◽  
Hongwei Du ◽  
...  

Pancreas divisum (PD) is a common pancreatic malformation caused by the failure of fusion between ventral and dorsal pancreatic ducts. There is a small branch of communication between the two systems in incomplete PD, and this variation has an incidence of 15%. A 43-year-old female patient presented to our department with recurrent abdominal pain. Magnetic resonance cholangiopancreatography (MRCP) showed that the ventral pancreatic duct was curved, with a local pouchlike dilatation. Endoscopic ultrasonography supported the diagnosis of incomplete PD and showed a thin branch of communication between ventral and dorsal pancreatic ducts. Endoscopic retrograde cholangiopancreatography (ERCP) and papillotomy of the minor papilla with double plastic stent implantation were performed. One pancreatic plastic stent was inserted across the minor and major papilla over the guide wire, creating a U-shape. The other wire-guided plastic stent was inserted through the minor papilla into the dorsal pancreatic duct. The pancreatic fluid drained smoothly after stent placement. During the 6-month follow-up, the patient remained well, without recurrence of pancreatitis.


2020 ◽  
Vol 15 (11) ◽  
pp. 2255-2258
Author(s):  
Shahab Shayesteh ◽  
Daniel Fadaei Fouladi ◽  
Alejandra Blanco ◽  
Elliot K. Fishman ◽  
Satomi Kawamoto

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