Pancreas divisum increases the risk of idiopathic recurrent acute pancreatitis in the presence of cathepsin B L26V polymorphism

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S47
Author(s):  
Mohsin Aslam ◽  
Steffie Avanthi ◽  
Govardhan Balle ◽  
V. Vishnubhotla Ravikanth ◽  
Zaheer Nabi ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Cathepsin B ◽  
Pancreas Divisum ◽  
Recurrent Acute Pancreatitis ◽  
Pancréas Divisum

Pancreas Divisum Increases the Risk of Idiopathic Recurrent Acute Pancreatitis in the Presence of Cathepsin B L26V polymorphism

2017 ◽  
Vol 15 (1) ◽  
pp. 154
Author(s):  
Mohsin Aslam ◽  
Steffie Avanthi ◽  
Vishnubhotla Ravikanth ◽  
Duvvuru Nageshwar Reddy ◽  
Rupjyoti Talukdar
Keyword(s):  
Acute Pancreatitis ◽  
Cathepsin B ◽  
Pancreas Divisum ◽  
Recurrent Acute Pancreatitis ◽  
Pancréas Divisum

scholarly journals Clinical outcome of endoscopic therapy in patients with symptomatic pancreas divisum: a Dutch cohort study

2021 ◽  
Vol 09 (07) ◽  
pp. E1164-E1170
Author(s):  
David M. de Jong ◽  
Pauline M. Stassen ◽  
Jan Werner Poley ◽  
Paul Fockens ◽  
Robin Timmer ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Cohort Study ◽  
Endoscopic Therapy ◽  
Clinical Success ◽  
Pancreas Divisum ◽  
Univariate Analysis ◽  
Clinical Success Rate ◽  
Recurrent Acute Pancreatitis ◽  
Pancréas Divisum

Abstract Background and study aims Although the majority of patients with pancreas divisum (PDiv) are asymptomatic, a subgroup present with recurrent pancreatitis or pain for which endoscopic therapy may be indicated. The aim of this study was to evaluate success rates and long-term outcomes of endoscopic treatment in patients with symptomatic PDiv. Patients and methods A multicenter, retrospective cohort study was performed. Patients with symptomatic PDiv presenting with recurrent acute pancreatitis (RAP), chronic pancreatitis (CP), or chronic abdominal pancreatic-type pain (CAP) who underwent endoscopic retrograde cholangiopancreatography (ERCP) between January 2000 and December 2019 were included. The primary outcome was clinical success, defined as either no recurrent episode of acute pancreatitis (AP) for RAP patients, no flares for CP patients, or absence of abdominal pain for patients with CAP after technically successful ERCP. Results In 60 of 81 patients (74.1 %) a technically successful papilla minor intervention was performed. Adverse events were reported in 30 patients (37 %), with post-ERCP pancreatitis in 18 patients. The clinical success rate for patients with at least 3 months of follow-up was 42.6 %, with higher rates of success among patients presenting with RAP (44.4 %) as compared to those with CP (33.3 %) or CAP (33.3 %). Long-term sustained response was present in 40.9 % of patients with a technically successful intervention. In patients with RAP who did not completely respond to treatment, the mean number of AP episodes after treatment decreased significantly from 3.5 to 1.1 per year, and subsequently the interval between AP episodes increased from 278 to 690 days (P = 0.0006). A potential predictive factor of failure of clinical success after technically successful ERCP, at univariate analysis, was male sex (OR = 0.25, P = 0.02). Conclusions Endoscopic therapy in patients with symptomatic PDiv is moderately effective, with its highest yield in patients presenting with RAP. Future studies are needed to assess factors predictive for success of endoscopic therapy and potential risk factors for relapse after ERCP.

Sa1503 Which Patients With Recurrent Acute Pancreatitis in the Setting of Pancreas Divisum Respond to Minor Sphincterotomy?

2016 ◽  
Vol 83 (5) ◽  
pp. AB275-AB276 ◽  
Author(s):  
Zachary A. Zator ◽  
Rohit Das ◽  
Rawad Mounzer ◽  
Arun Mannem ◽  
Dhiraj Yadav ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Pancreas Divisum ◽  
Recurrent Acute Pancreatitis ◽  
Pancréas Divisum

scholarly journals Duodenal Web and Pancreas Divisum Causing Pancreatitis in an Adult

HPB Surgery ◽  
1994 ◽  
Vol 7 (3) ◽  
pp. 231-235 ◽  
Author(s):  
J. Kollias ◽  
J. Toouli
Keyword(s):  
Acute Pancreatitis ◽  
Intestinal Obstruction ◽  
Clinical Characteristics ◽  
Pancreas Divisum ◽  
Recurrent Acute Pancreatitis ◽  
The Third ◽  
Pancréas Divisum ◽  
Duodenal Web

Duodenal malformations are the third commonest cause of intestinal obstruction in infants1. A spectrum of intrinsic obstructive lesions within the duodenum ranges from atresia to congenital bands2. Rarely, duodenal malformations may first present in adulthood. Less than 70 cases of duodenal web presenting in an adult have been reported in the literature. In 10 patients the presentation was associated with pancreatitis. We report a case of congenital duodenal web associated with pancreas divisum which first presented in an adult with the clinical characteristics of recurrent acute pancreatitis.

scholarly journals Idiopathic recurrent acute pancreatitis in the context of pancreas divisum: A case report

2020 ◽  
Vol 15 (11) ◽  
pp. 2255-2258
Author(s):  
Shahab Shayesteh ◽  
Daniel Fadaei Fouladi ◽  
Alejandra Blanco ◽  
Elliot K. Fishman ◽  
Satomi Kawamoto
Keyword(s):  
Acute Pancreatitis ◽  
Case Report ◽  
Pancreas Divisum ◽  
Recurrent Acute Pancreatitis ◽  
Pancréas Divisum
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