Sensitization of Peripheral Sensory Nerves by Mediators From Colonic Biopsies of Diarrhea-Predominant Irritable Bowel Syndrome Patients: A Role for PAR2

2013 ◽  
Vol 108 (10) ◽  
pp. 1634-1643 ◽  
Author(s):  
Eduardo E Valdez-Morales ◽  
Jeff Overington ◽  
Raquel Guerrero-Alba ◽  
Fernando Ochoa-Cortes ◽  
Charles O Ibeakanma ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Sensory Nerves ◽  
Irritable Bowel ◽  
Peripheral Sensory ◽  
Colonic Biopsies

scholarly journals Excitation of Enteric Neurons by Supernatants of Colonic Biopsies From Irritable Bowel Syndrome Patients (IBS) is Linked to Visceral Sensitivity

2011 ◽  
Vol 140 (5) ◽  
pp. S-521 ◽  
Author(s):  
Sabine Buhner ◽  
Qin Li ◽  
Breg Braak ◽  
Tamira K. Klooker ◽  
Sheila Vignali ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Enteric Neurons ◽  
Visceral Sensitivity ◽  
Irritable Bowel ◽  
Colonic Biopsies

scholarly journals Mucosal Tuft Cell Density Is Increased in Diarrhea-Predominant Irritable Bowel Syndrome Colonic Biopsies

2020 ◽  
Vol 11 ◽  
Author(s):  
Jessica Aigbologa ◽  
Maeve Connolly ◽  
Julliette M. Buckley ◽  
Dervla O'Malley
Keyword(s):  
Irritable Bowel Syndrome ◽  
Cell Density ◽  
Tuft Cell ◽  
Irritable Bowel ◽  
Colonic Biopsies

A Study of Microbial Diversity in Colonic Biopsies of Patients With Irritable Bowel Syndrome in Mexico Using High-Throughput Sequencing

2017 ◽  
Vol 112 ◽  
pp. S240-S241
Author(s):  
Max Schmulson ◽  
Samuel Ponce de León ◽  
Angel Mario Zárate ◽  
Patricia Orduña ◽  
Rubí Santiago-Cruz ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Microbial Diversity ◽  
High Throughput ◽  
High Throughput Sequencing ◽  
Irritable Bowel ◽  
Colonic Biopsies

366 Guanylate Cyclase-C Expression Is Down-Regulated in Colonic Biopsies From Female Irritable Bowel Syndrome Patients With Constipation

2016 ◽  
Vol 150 (4) ◽  
pp. S81-S82 ◽  
Author(s):  
Sonia Garcia-Carraballo ◽  
Andrea Harrington ◽  
Joel Castro ◽  
Gerhard Hannig ◽  
Caroline B. Kurtz ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Guanylate Cyclase ◽  
Guanylate Cyclase C ◽  
Irritable Bowel ◽  
Colonic Biopsies

Membrane-associated microtubular areays induced in proximal myelinated processes of dorsal root ganglia by large doses of vitamin B6

1986 ◽  
Vol 44 ◽  
pp. 368-369
Author(s):  
V.J. Montpetit ◽  
S. Dancea ◽  
L. Tryphonas ◽  
D.F. Clapin
Keyword(s):  
Animal Model ◽  
Endoplasmic Reticulum ◽  
Dorsal Root Ganglia ◽  
Rough Endoplasmic Reticulum ◽  
Dorsal Root ◽  
Vitamin B6 ◽  
Morphological Changes ◽  
Model System ◽  
Sensory Nerves ◽  
Peripheral Sensory

Very large doses of pyridoxine (vitamin B6) are neurotoxic in humans, selectively affecting the peripheral sensory nerves. We have undertaken a study of the morphological and biochemical aspects of pyridoxine neurotoxicity in an animal model system. Early morphological changes in dorsal root ganglia (DRG) associated with pyridoxine megadoses include proliferation of neurofilaments, ribosomes, rough endoplasmic reticulum, and Golgi complexes. We present in this report evidence of the formation of unique aggregates of microtubules and membranes in the proximal processes of DRG which are induced by high levels of pyridoxine.

Motor and sensory function of the rectum in different types of irritable bowel syndrome

2001 ◽  
Vol 120 (5) ◽  
pp. A399-A399
Author(s):  
J STEENS ◽  
P SCHAAR ◽  
C LAMERS ◽  
A MASCLEE
Keyword(s):  
Irritable Bowel Syndrome ◽  
Sensory Function ◽  
Different Types ◽  
Irritable Bowel
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