Erratum: Neither Diabetes Mellitus nor Overweight Is a Risk Factor for Hepatocellular Carcinoma in a Dual HBV and HCV Endemic Area: Community Cross-Sectional and Case–Control Studies

2010 ◽  
Vol 105 (6) ◽  
pp. 1455
Author(s):  
Hung-Da Tung ◽  
Jing-Houng Wang ◽  
Po-Lin Tseng ◽  
Chao-Hung Hung ◽  
Kwong-Ming Kee ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hepatocellular Carcinoma ◽  
Risk Factor ◽  
Endemic Area ◽  
Case Control ◽  
Case Control Studies ◽  
Cross Sectional

scholarly journals Is Diabetes Mellitus a Risk Factor for Intrahepatic and Extrahepatic Cholangiocarcinoma?: A Meta-Analysis of Case Control Studies

2011 ◽  
Vol 140 (5) ◽  
pp. S-919
Author(s):  
Abdul S. Khan ◽  
Priyanka Tiwari ◽  
Jonathan P. Nass ◽  
Tuhama Rihani ◽  
Brian B. Borg ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Meta Analysis ◽  
Case Control ◽  
Case Control Studies ◽  
Extrahepatic Cholangiocarcinoma

scholarly journals Diabetes Mellitus as a Risk Factor for Trigger Finger –a Longitudinal Cohort Study Over More Than 20 Years

2021 ◽  
Vol 2 ◽  
Author(s):  
Jin Persson Löfgren ◽  
Malin Zimmerman ◽  
Lars B. Dahlin ◽  
Peter M. Nilsson ◽  
Mattias Rydberg
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Cohort Study ◽  
Population Based ◽  
Trigger Finger ◽  
Case Control Studies ◽  
Cross Sectional ◽  
Kaplan Meier ◽  
National Patient ◽  
Cox Proportional Hazard Regression

Background and AimTrigger finger (TF) or stenosing tenosynovitis has been associated with diabetes mellitus (DM), although today’s knowledge is mostly based on cross-sectional and case-control studies. Thus, the aim of the present population-based cohort study over more than 20 years was to investigate DM as a risk factor for TF.MethodsData from Malmö Diet and Cancer Study (MDCS), including 30,446 individuals, were analysed with regards to baseline DM and known or potential confounders. Information regarding TF diagnosis until study end date of Dec 31st, 2018, was retrieved from the Swedish National Patient Register (NPR) using ICD-codes. Survival probability was investigated in Kaplan-Meier plots. Cox proportional hazard regression model was used to evaluate DM as risk factor for TF, adjusted for several confounders and presented as Hazard Ratio (HR) with 95% confidence intervals (CI).ResultsAt baseline, 4.6% (1,393/30,357) participants had DM. In total, 3.2% (974/30,357) participants were diagnosed with TF during the study period. Kaplan-Meier plot showed that the probability for incident TF was significantly higher in participants with baseline DM compared with individuals without baseline DM. Adjusted HR for DM as risk factor for TF was 2.0 (95% CI: 1.5-2.6, p<0.001).ConclusionThis longitudinal study showed that DM is an important risk factor for developing TF. When adjusting for sex, age, BMI, manual work, statin use, smoking and alcohol consumption, DM remained the main risk factor for TF.

scholarly journals Diabetes Mellitus Is Associated with Hepatocellular Carcinoma: A Retrospective Case-Control Study in Hepatitis Endemic Area

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e84776 ◽  
Author(s):  
Ze Zheng ◽  
Chao Zhang ◽  
Jianhua Yan ◽  
Yanping Ruan ◽  
Xiaoyi Zhao ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hepatocellular Carcinoma ◽  
Endemic Area ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Control Study

scholarly journals Is chronic toxoplasmosis a risk factor for diabetes mellitus? A systematic review and meta-analysis of case–control studies

2016 ◽  
Vol 20 (6) ◽  
pp. 605-609 ◽  
Author(s):  
Hamidreza Majidiani ◽  
Sahar Dalvand ◽  
Ahmad Daryani ◽  
Ma de la Luz Galvan-Ramirez ◽  
Masoud Foroutan-Rad
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Risk Factor ◽  
Meta Analysis ◽  
Case Control ◽  
Case Control Studies

scholarly journals The Effect of Prophylactic HPV Vaccines on Oral and Oropharyngeal HPV Infection—A Systematic Review

Viruses ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1339
Author(s):  
Kristoffer Juul Nielsen ◽  
Kathrine Kronberg Jakobsen ◽  
Jakob Schmidt Jensen ◽  
Christian Grønhøj ◽  
Christian Von Buchwald
Keyword(s):  
Cohort Study ◽  
Oropharyngeal Cancer ◽  
Hpv Infection ◽  
Case Control ◽  
Igg Antibodies ◽  
Hpv Vaccines ◽  
Case Control Studies ◽  
Cross Sectional ◽  
Post Vaccination ◽  
Cross Sectional Studies

Human papillomavirus (HPV) imposes an increased risk of developing cervical, anal and oropharyngeal cancer. In the Western world, HPV infection is currently the major cause of oropharyngeal cancer. The effectiveness of HPV vaccines for oral or oropharyngeal HPV infection is yet to be determined. This study conducted a systematic literature search in Pubmed and Embase. Studies investigating the impact of HPV vaccines on oral or oropharyngeal HPV infection were enrolled. This review reports the relative prevention percentage (RPP), including a risk of bias assessment as well as a quality assessment study. Nine studies were included (48,777 participants): five cross-sectional studies; one randomized community trial study (RCT); one longitudinal cohort study; and two case-control studies. A significant mean RPP of 83.9% (66.6–97.8%) was calculated from the cross-sectional studies, 82.4% in the included RCT and 83% in the longitudinal cohort study. Further, two case-control studies that measured antibody response in participants immunized with HPV vaccines were included. Respectively, 100% and 93.2% of participants developed HPV-16 Immunoglobulin G (IgG) antibodies in oral fluids post-vaccination. Analysis of the studies identified a significant decrease in vaccine-type oral or oropharyngeal HPV infections in study participants immunized with HPV vaccines across study designs and heterogenous populations. Further, a significant percentage of participants developed IgG antibodies in oral fluid post-vaccination.

scholarly journals Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case–control study

2008 ◽  
Vol 89 (11) ◽  
pp. 2882-2890 ◽  
Author(s):  
Zhong-Liao Fang ◽  
Caroline A. Sabin ◽  
Bai-Qing Dong ◽  
Shao-Chao Wei ◽  
Qin-Yan Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Risk Factor ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Case Control Study ◽  
Case Control ◽  
Deletion Mutations ◽  
B Virus ◽  
Nested Case Control ◽  
Control Study

A matched nested case–control study of 33 paired cases and controls was conducted, based on a study cohort in Long An county, Guangxi, China, to determine whether infection with hepatitis B virus (HBV) with pre-S deletions is independently associated with the development of hepatocellular carcinoma (HCC), without the confounding effects of basal core promoter (BCP) double mutations. The prevalence of pre-S deletions was significantly higher in HCC (45.5 %, 15 of 33) than the controls (18.2 %, 6 of 33) (P<0.01), under the control of the influence of BCP double mutations. Most of the pre-S deletions occurred in, or involved, the 5′ half of the pre-S2 region and the difference between HCC (93.3 %, 14 of 15) and controls (66.7 %, four of six) was significant for this region (P=0.015). There was no significant difference in pre-S deletions between the BCP mutant group and BCP wild-type group (P>0.05), nor was the prevalence of pre-S deletions significantly different between genotypes B and C (P>0.1). These results suggest that pre-S deletions constitute an independent risk factor for HCC and their emergence and effect are independent of BCP mutations. The 5′ terminus of pre-S2 is the favoured site for the deletion mutations, especially in HCC cases. Further prospective studies are required to confirm the role of these mutations in the development of HCC.

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