A base pair between tRNA and 23S rRNA in the peptidyl transferase centre of the ribosome

Raymond R. Samaha; Rachel Green; Harry F. Noller

doi:10.1038/377309a0

A base pair between tRNA and 23S rRNA in the peptidyl transferase centre of the ribosome

Nature ◽

10.1038/377309a0 ◽

1995 ◽

Vol 377 (6547) ◽

pp. 309-314 ◽

Cited By ~ 152

Author(s):

Raymond R. Samaha ◽

Rachel Green ◽

Harry F. Noller

Keyword(s):

Base Pair ◽

23S Rrna ◽

Peptidyl Transferase ◽

Peptidyl Transferase Centre

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A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre

Molecular Microbiology ◽

10.1046/j.1365-2958.1999.01203.x ◽

1999 ◽

Vol 31 (2) ◽

pp. 633-639 ◽

Cited By ~ 128

Author(s):

Liqun Xiong ◽

Sunita Shah ◽

Pascale Mauvais ◽

Alexander S. Mankin

Keyword(s):

Resistance Mutation ◽

23S Rrna ◽

Peptidyl Transferase ◽

Peptidyl Transferase Centre

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Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics inMycobacterium smegmatisby perturbation of the drug binding pocket

Molecular Microbiology ◽

10.1111/j.1365-2958.2009.06596.x ◽

2009 ◽

Vol 71 (5) ◽

pp. 1218-1227 ◽

Cited By ~ 43

Author(s):

Katherine S. Long ◽

Jacob Poehlsgaard ◽

Lykke H. Hansen ◽

Sven N. Hobbie ◽

Erik C. Böttger ◽

...

Keyword(s):

Binding Pocket ◽

Drug Binding ◽

23S Rrna ◽

Peptidyl Transferase ◽

Peptidyl Transferase Centre

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A base pair between tRNA and 235 rRNA in the peptidyl transferase centre of the ribosome

Nature ◽

10.1038/378419f0 ◽

1995 ◽

Vol 378 (6555) ◽

pp. 419-419 ◽

Cited By ~ 1

Author(s):

Raymond R. Samaha ◽

Rachel Green ◽

Harry F. Noller

Keyword(s):

Base Pair ◽

Peptidyl Transferase ◽

Peptidyl Transferase Centre

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Photo-affinity labelling at the peptidyl transferase centre reveals two different positions for the A- and P-sites in domain V of 23S rRNA.

The EMBO Journal ◽

10.1002/j.1460-2075.1988.tb03281.x ◽

1988 ◽

Vol 7 (12) ◽

pp. 3949-3955 ◽

Cited By ~ 74

Author(s):

G. Steiner ◽

E. Kuechler ◽

A. Barta

Keyword(s):

23S Rrna ◽

Peptidyl Transferase ◽

Affinity Labelling ◽

Peptidyl Transferase Centre ◽

Domain V

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Interaction of Arginine with the Ribosomal Peptidyl Transferase Centre

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1979.tb19741.x ◽

1979 ◽

Vol 101 (2) ◽

pp. 469-473 ◽

Cited By ~ 4

Author(s):

Enrique PALACIAN ◽

David VAZQUEZ

Keyword(s):

Peptidyl Transferase ◽

Peptidyl Transferase Centre

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Structure of a conserved RNA component of the peptidyl transferase centre

Natural Structural Biology ◽

10.1038/nsb1097-775 ◽

1997 ◽

Vol 4 (10) ◽

pp. 775-778 ◽

Cited By ~ 25

Author(s):

Elisabetta Viani Puglisi ◽

Rachel Green ◽

Harry F. Noller ◽

Joseph D. Puglisi

Keyword(s):

Peptidyl Transferase ◽

Peptidyl Transferase Centre

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UV-induced modifications in the peptidyl transferase loop of 23S rRNA dependent on binding of the streptogramin B antibiotic, pristinamycin IA

RNA ◽

10.1017/s135583829998202x ◽

1999 ◽

Vol 5 (4) ◽

pp. 585-595 ◽

Cited By ~ 11

Author(s):

BO T. PORSE ◽

STANISLAV V. KIRILLOV ◽

MARIANA J. AWAYEZ ◽

ROGER A. GARRETT

Keyword(s):

23S Rrna ◽

Peptidyl Transferase

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Peptidyl transferase antibiotics perturb the relative positioning of the 3′-terminal adenosine of P/P′-site-bound tRNA and 23S rRNA in the ribosome

RNA ◽

10.1017/s1355838299990568 ◽

1999 ◽

Vol 5 (8) ◽

pp. 1003-1013 ◽

Cited By ~ 22

Author(s):

STANISLAV V. KIRILLOV ◽

BO T. PORSE ◽

ROGER A. GARRETT

Keyword(s):

23S Rrna ◽

Relative Positioning ◽

Peptidyl Transferase

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23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A->G

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0501598102 ◽

2005 ◽

Vol 102 (14) ◽

pp. 5180-5185 ◽

Cited By ~ 58

Author(s):

P. Pfister ◽

N. Corti ◽

S. Hobbie ◽

C. Bruell ◽

R. Zarivach ◽

...

Keyword(s):

Base Pair ◽

Resistance Mutation ◽

Macrolide Resistance ◽

Fitness Cost ◽

23S Rrna

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Identifying the peptidyl transferase centre

Trends in Biochemical Sciences ◽

10.1016/0968-0004(82)90175-x ◽

1982 ◽

Vol 7 (11) ◽

pp. 385-386 ◽

Cited By ~ 14

Author(s):

R.A. Garrett ◽

Paul Wooley

Keyword(s):

Peptidyl Transferase ◽

Peptidyl Transferase Centre

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