Culture of human malaria parasites Plasmodium falciparum

Nature ◽  
1976 ◽  
Vol 263 (5580) ◽  
pp. 767-769 ◽  
Author(s):  
J. DAVID HAYNES ◽  
CARTER L. DIGGS ◽  
FRED A. HINES ◽  
ROBERT E. DESJARDINS
Keyword(s):  
Plasmodium Falciparum ◽  
Malaria Parasites ◽  
Human Malaria

scholarly journals Long-Lived Antibody and B Cell Memory Responses to the Human Malaria Parasites, Plasmodium falciparum and Plasmodium vivax

2010 ◽  
Vol 6 (2) ◽  
pp. e1000770 ◽  
Author(s):  
Jiraprapa Wipasa ◽  
Chaisuree Suphavilai ◽  
Lucy C. Okell ◽  
Jackie Cook ◽  
Patrick H. Corran ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
B Cell ◽  
Plasmodium Vivax ◽  
Malaria Parasites ◽  
Cell Memory ◽  
Human Malaria ◽  
B Cell Memory

scholarly journals Apicoplast and Mitochondrion in Gametocytogenesis of Plasmodium falciparum

2008 ◽  
Vol 8 (1) ◽  
pp. 128-132 ◽  
Author(s):  
Noriko Okamoto ◽  
Timothy P. Spurck ◽  
Christopher D. Goodman ◽  
Geoffrey I. McFadden
Keyword(s):  
Plasmodium Falciparum ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Maternal Inheritance ◽  
Live Cell ◽  
Close Connection ◽  
Morphological Development ◽  
Malaria Parasites ◽  
Human Malaria ◽  
Male Gametes

ABSTRACT Live cell imaging of human malaria parasites Plasmodium falciparum during gametocytogenesis revealed that the apicoplast does not grow, whereas the mitochondrion undergoes remarkable morphological development. A close connection of the two organelles is consistently maintained. The apicoplast and mitochondrion are not components of the male gametes, suggesting maternal inheritance.

scholarly journals Plasmodium falciparum

2017 ◽  
Vol 1 (6) ◽  
pp. 517-523
Author(s):  
Catherine J. Merrick
Keyword(s):  
Plasmodium Falciparum ◽  
Plasmodium Species ◽  
Great Majority ◽  
Protozoan Parasite ◽  
Severe Form ◽  
Global Burden ◽  
Human Pathogen ◽  
African Region ◽  
Malaria Parasites ◽  
Human Malaria

Plasmodium falciparum is a protozoan parasite that causes the most severe form of human malaria. Five other Plasmodium species can also infect humans — P. vivax, P. malariae, P. ovale curtisi, P. ovale wallikeri and P. knowlesi — but P. falciparum is the most prevalent Plasmodium species in the African region, where 90% of all malaria occurs, and it is this species that causes the great majority of malaria deaths. These were reported by the WHO at 438 000 in 2015 from an estimated 214 million cases; importantly, however, figures for the global burden of malaria tend to have wide margins of error due to poor and inaccurate reporting. In this Perspective, features of P. falciparum that are unique among human malaria parasites are highlighted, and current issues surrounding the control and treatment of this major human pathogen are discussed.

scholarly journals Can Mixed Parasite Infections Thwart Targeted Malaria Elimination Program in India?

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Upasana Shyamsunder Singh ◽  
Nisha Siwal ◽  
Veena Pande ◽  
Aparup Das
Keyword(s):  
Plasmodium Falciparum ◽  
Malaria Elimination ◽  
Disease Burden ◽  
Parasitic Infections ◽  
Published Data ◽  
Diagnostic Assay ◽  
Mixed Species ◽  
Malaria Parasites ◽  
Human Malaria ◽  
Parasite Infections

India is highly endemic to malaria with prevalence of all five species of human malaria parasites of Plasmodium genus. India is set for malaria elimination by 2030. Since cases of mixed Plasmodium species infections remain usually undetected but cause huge disease burden, in order to understand the distributional prevalence of both monospecies infections and mixed species infections in India, we collated published data on the differential infection incidences of the five different malaria parasites based on PCR diagnostic assay. About 11% of total cases were due to mixed species infection. Among several interesting observations on both single and mixed parasitic infections, incidences of Plasmodium falciparum monoinfection were found to be significantly higher than P. vivax monoinfection. Also, P. malariae seems to be emerging as a potential malaria threat in India. Putting all the facts together, it appears that the dream of achieving malaria elimination in India will not be completely successful without dealing with mixed species infection.

scholarly journals Out of Africa: origins and evolution of the human malaria parasites Plasmodium falciparum and Plasmodium vivax

2017 ◽  
Vol 47 (2-3) ◽  
pp. 87-97 ◽  
Author(s):  
Dorothy E. Loy ◽  
Weimin Liu ◽  
Yingying Li ◽  
Gerald H. Learn ◽  
Lindsey J. Plenderleith ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Plasmodium Vivax ◽  
Malaria Parasites ◽  
Human Malaria ◽  
Out Of Africa

scholarly journals A glimpse into the clinical proteome of human malaria parasites Plasmodium falciparum and Plasmodium vivax

2009 ◽  
Vol 3 (11) ◽  
pp. 1314-1325 ◽  
Author(s):  
Pragyan Acharya ◽  
Rani Pallavi ◽  
Syama Chandran ◽  
Harshini Chakravarti ◽  
Sheetal Middha ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Plasmodium Vivax ◽  
Malaria Parasites ◽  
Human Malaria
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