An uncommon nucleotide conformation shown by molecular structure of deoxyuridine-5′-phosphate and nucleic acid stereochemistry

Nature ◽  
1975 ◽  
Vol 258 (5535) ◽  
pp. 542-544 ◽  
Author(s):  
M. A. VISWAMITRA ◽  
T. P. SESHADRI ◽  
M. L. POST
Keyword(s):  
Molecular Structure ◽  
Nucleic Acid ◽  
Nucleotide Conformation

scholarly journals The molecular structure effect of cationic comb-type copolymers on nucleic acid chaperone activity

2005 ◽  
Vol 49 (1) ◽  
pp. 329-330 ◽  
Author(s):  
Sung Won Choi ◽  
Kaoru Takada ◽  
Junji Mochida ◽  
Asako Yamayosh ◽  
Arihiro Kano ◽  
...  
Keyword(s):  
Molecular Structure ◽  
Nucleic Acid ◽  
Chaperone Activity ◽  
Structure Effect ◽  
Nucleic Acid Chaperone

CHIASMUS IN ART AND TEXT

2013 ◽  
Vol 60 (1) ◽  
pp. 50-88
Author(s):  
Edmund Thomas
Keyword(s):  
Molecular Structure ◽  
Twentieth Century ◽  
Nucleic Acid ◽  
Nucleic Acids ◽  
Double Helix ◽  
Scientific Article ◽  
Deoxyribose Nucleic Acid ◽  
Francis Crick

Sixty years ago, on 25 April 1953, probably the most influential scientific article of the twentieth century appeared. Its uninviting title, ‘Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid’, concealed the revolutionary discovery by the molecular biologists James Watson and Francis Crick of the structure of what became known as ‘the molecule of life’. The ‘radically different structure’ that they proposed for the salt of deoxyribose nucleic acid (DNA) had ‘two helical chains each coiled round the same axis’. ‘Both chains’, they wrote, ‘follow right-handed helices, but owing to the dyad the sequences of the atoms in the two chains run in opposite directions.’ When Bruno J. Strasser asked in the same journal fifty years later ‘Who cares about the double helix?’, he answered that it marked ‘an age of (lost) innocence, when youth, intelligence and self-assurance were sufficient to make great discoveries in science’.

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