Astrocyte-specific protein and radial glia in the cerebral cortex of newborn rat

Nature ◽  
1974 ◽  
Vol 252 (5478) ◽  
pp. 55-56 ◽  
Author(s):  
A. BIGNAMI ◽  
D. DAHL
Keyword(s):  
Cerebral Cortex ◽  
Radial Glia ◽  
Specific Protein ◽  
Newborn Rat

Radial glia is a progenitor of neocortical neurons in the developing cerebral cortex

2001 ◽  
Vol 41 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Nobuaki Tamamaki ◽  
Kouichi Nakamura ◽  
Keiko Okamoto ◽  
Takeshi Kaneko
Keyword(s):  
Cerebral Cortex ◽  
Radial Glia ◽  
Neocortical Neurons

scholarly journals Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex

2003 ◽  
Vol 100 (7) ◽  
pp. 4251-4256 ◽  
Author(s):  
R. S. Schmid ◽  
B. McGrath ◽  
B. E. Berechid ◽  
B. Boyles ◽  
M. Marchionni ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Radial Glia ◽  
Neuregulin 1 ◽  
Erbb2 Signaling

scholarly journals Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Congyun Jin ◽  
Atsushi Yonezawa ◽  
Hiroki Yoshimatsu ◽  
Satoshi Imai ◽  
Madoka Koyanagi ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Gene Disruption ◽  
Radial Glia ◽  
Neural Progenitors ◽  
Cortical Layers ◽  
Riboflavin Deficiency ◽  
Proliferative Rate ◽  
Neonatal Lethality ◽  
Significant Difference ◽  
The Brain

Abstract Riboflavin transporter 3 (RFVT3), encoded by the SLC52A3 gene, is important for riboflavin homeostasis in the small intestine, kidney, and placenta. Our previous study demonstrated that Slc52a3 knockout (Slc52a3−/−) mice exhibited neonatal lethality and metabolic disorder due to riboflavin deficiency. Here, we investigated the influence of Slc52a3 gene disruption on brain development using Slc52a3−/− embryos. Slc52a3−/− mice at postnatal day 0 showed hypoplasia of the brain and reduced thickness of cortical layers. At embryonic day 13.5, the formation of Tuj1+ neurons and Tbr2+ intermediate neural progenitors was significantly decreased; no significant difference was observed in the total number and proliferative rate of Pax6+ radial glia. Importantly, the hypoplastic phenotype was rescued upon riboflavin supplementation. Thus, it can be concluded that RFVT3 contributes to riboflavin homeostasis in embryos and that riboflavin itself is required during embryonic development of the cerebral cortex in mice.

Characterization and identification of Sox2+ radial glia cells derived from rat embryonic cerebral cortex

2011 ◽  
Vol 136 (5) ◽  
pp. 515-526 ◽  
Author(s):  
Haoming Li ◽  
Guohua Jin ◽  
Jianbing Qin ◽  
Meiling Tian ◽  
Jinhong Shi ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Radial Glia ◽  
Glia Cells

scholarly journals p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex

Development ◽  
2012 ◽  
Vol 139 (3) ◽  
pp. 475-487 ◽  
Author(s):  
G. Mairet-Coello ◽  
A. Tury ◽  
E. Van Buskirk ◽  
K. Robinson ◽  
M. Genestine ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cerebral Cortex ◽  
Radial Glia ◽  
Lower Layer ◽  
Precursor Cell ◽  
Cell Cycle Dynamics
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