Role of Acetylcholine and Vitamin B1 in Nervous Excitation

Nature ◽  
1944 ◽  
Vol 154 (3920) ◽  
pp. 767-768 ◽  
Author(s):  
A. v. MURALT
Keyword(s):  
Vitamin B1 ◽  
Nervous Excitation

Role of Acetylcholine and Vitamin B1 in Nervous Excitation

Nature ◽  
1943 ◽  
Vol 152 (3850) ◽  
pp. 188-189 ◽  
Author(s):  
A. V. MURALT
Keyword(s):  
Vitamin B1 ◽  
Nervous Excitation

scholarly journals The Role of Neurotropic B Vitamins in Nerve Regeneration

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Simone Baltrusch
Keyword(s):  
Vitamin B12 ◽  
Vitamin B6 ◽  
Vitamin B1 ◽  
B Vitamins ◽  
Nerve Degeneration ◽  
Antioxidant Vitamin ◽  
Neuronal Viability ◽  
Cell Structures ◽  
A Site

Damage and regeneration naturally occur in the peripheral nervous system. The neurotropic B vitamins thiamine (B1), pyridoxine (B6), and cobalamin (B12) are key players, which maintain the neuronal viability in different ways. Firstly, they constantly protect nerves against damaging environmental influences. While vitamin B1 acts as a site-directed antioxidant, vitamin B6 balances nerve metabolism, and vitamin B12 maintains myelin sheaths. However, nerve injury occurs at times, because of an imbalance between protective factors and accumulating stress and noxae. This will result in the so-called Wallerian degeneration process. The presence of vitamins B1, B6, and B12 paves the way out to the following important regeneration by supporting the development of new cell structures. Furthermore, vitamin B1 facilitates the usage of carbohydrates for energy production, whereas vitamin B12 promotes nerve cell survival and remyelination. Absence of these vitamins will favor permanent nerve degeneration and pain, eventually leading to peripheral neuropathy.

scholarly journals Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1034 ◽  
Author(s):  
Reza Ehsanian ◽  
Sean Anderson ◽  
Byron Schneider ◽  
David Kennedy ◽  
Vartgez Mansourian
Keyword(s):  
Thiamine Deficiency ◽  
Medical Center ◽  
Academic Medical Center ◽  
Vitamin B1 ◽  
Inpatient Rehabilitation ◽  
Plasma Vitamin ◽  
Stroke Service ◽  
Rehabilitation Facility ◽  
Stroke Population

Objective: To determine the prevalence of vitamin B1 (VitB1) deficiency in the stroke population admitted to acute inpatient rehabilitation. Design: Retrospective cohort study. Setting: Acute inpatient rehabilitation facility at an academic medical center. Participants: 119 consecutive stroke patients admitted to stroke service from 1 January 2018 to 31 December 2018. Interventions: Not applicable. Main Outcome Measures: Plasma VitB1 level. Results: There were 17 patients (14%; 95% CI 9–22%) with low VitB1 with a range of 2–3 nmol/L, an additional 58 (49%; CI 40–58%) patients had normal low VitB1 with a range of 4–9 nmol/L, twenty-five patients (21%; CI 15–29%) had normal high VitB1 with a range of 10–15 nmol/L, and nineteen patients (16%; CI 10–24%) had high VitB1 with a range of 16–43 nmol/L. Conclusions: In this cohort of patients admitted to the stroke service at an acute rehabilitation facility, there is evidence of thiamine deficiency. Moreover, the data suggest that there is inadequate acute intake of VitB1. Given the role of thiamine deficiency in neurologic function, further study of the role of thiamine optimization in the acute stroke rehabilitation population is warranted.

scholarly journals The role of thiamine as a resuscitator in patients with nonalcoholic medical and CNS disorders

2017 ◽  
Vol 5 (19) ◽  
pp. 11 ◽  
Author(s):  
Mohamed Shehab-Eldin
Keyword(s):  
Septic Shock ◽  
Side Effects ◽  
Thiamine Deficiency ◽  
Vitamin B1 ◽  
Water Soluble ◽  
Essential Factor ◽  
Cns Disorders ◽  
Water Soluble Vitamin

Thiamine (vitamin B1), a water-soluble vitamin, is an essential factor in cellular metabolismand fundamental cofactor in important biochemical cycles. Thiamine deficiency is a wellknowncause of neurological and cardiologic disorders, especially in patients with alcoholdependence. Recently, several researchers have studied the role of thiamine deficiency incritically ill patients and the link between thiamine supplementation and changes in lactatelevels in septic shock patients. The role of thiamine in this group of patients is still unclear;however, thiamine supplementation does not cause toxic side effects or increase morbidityor mortality. In this review, we discuss the most common conditions associated with thiaminedeficiency and the limited literature available on thiamine supplementation in critically illpatients.

P414 THE ROLE OF VITAMIN B1 IN LACTATE METABOLISM DURING FRUCTOSE INFUSION IN OPERATED PATIENTS

2008 ◽  
Vol 3 ◽  
pp. 204
Author(s):  
Z. Sundov ◽  
Z. Nincevic ◽  
S. Tomic ◽  
J. Nincevic ◽  
A. Ujevic
Keyword(s):  
Vitamin B1 ◽  
Lactate Metabolism

scholarly journals ROLE OF MICRONUTRIENTS IN HEART DISEASES

2021 ◽  
pp. 1-5
Author(s):  
NAMRATA KHAIRNAR ◽  
PRASHANT PINGALE ◽  
SUNIL AMRUTKAR
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Older Patients ◽  
Aging Process ◽  
Heart Diseases ◽  
Vitamin B1 ◽  
Selenium Deficiency ◽  
Coronary Heart Diseases

Heart disease is a common occurrence in older patients in the civilized culture, and the rate is predicted to rise as the software advances. Patients with heart disease should be intended to eat a salt-free diet to lose adiposity. Diet is also critical for heart disease patients; those with nutrition deficits have a low deep prognosis. A growing body of research indicates a correlation between heart disease and a lack of micronutrients. Repairable heart disease has been linked to thiamine and selenium deficiency. Micronutrients and heart disease may, nevertheless, have a more moderate association, according to recent research. This article looks at studies that looked at micronutrient consumption, supplement effectiveness, and micronutrient ingestion in heart disease patients, with an emphasis on retinol, ascorbic acid, a fat-soluble vitamin, vitamin B1, other B vitamins, cholecalciferol, folate, iron, and copper. Because aging is the leading cause of coronary heart disease, treatments intended to reduce down the aging process or improving life expectancy are distinctly different from their standards for the treatment of coronary heart disease. Altering risky life decisions which might relate to aging and coronary heart diseases, such as nicotine usage, obesity, and unique lifestyles, is increasingly become part of the quality of practice.

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