The Genetics of Domestic Rabbits: a Manual for Students of Mammalian Genetics and an Aid to Rabbit Breeders and Fur Farmers

Nature ◽  
1931 ◽  
Vol 127 (3214) ◽  
pp. 847-848
Author(s):  
F. A. E. CREW
Keyword(s):  
Mammalian Genetics ◽  
Domestic Rabbits

scholarly journals Microbial metagenomic approach uncovers the first rabbit haemorrhagic disease virus genome in Sub-Saharan Africa

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Anise N. Happi ◽  
Olusola A. Ogunsanya ◽  
Judith U. Oguzie ◽  
Paul E. Oluniyi ◽  
Alhaji S. Olono ◽  
...  
Keyword(s):  
Virus Genome ◽  
Sub Saharan Africa ◽  
High Morbidity ◽  
Vp60 Gene ◽  
Band Size ◽  
Rabbit Haemorrhagic Disease ◽  
Sub Saharan ◽  
Domestic Rabbits ◽  
Haemorrhagic Disease ◽  
Pcr Targeting

AbstractRabbit Haemorrhagic Disease (RHD) causes high morbidity and mortality in rabbits and hares. Here, we report the first genomic characterization of lagovirus GI.2 virus in domestic rabbits from sub-Saharan Africa. We used an unbiased microbial metagenomic Next Generation Sequencing (mNGS) approach to diagnose the pathogen causing the suspected outbreak of RHD in Ibadan, Nigeria. The liver, spleen, and lung samples of five rabbits from an outbreak in 2 farms were analyzed. The mNGS revealed one full and two partial RHDV2 genomes on both farms. Phylogenetic analysis showed close clustering with RHDV2 lineages from Europe (98.6% similarity with RHDV2 in the Netherlands, and 99.1 to 100% identity with RHDV2 in Germany), suggesting potential importation. Subsequently, all the samples were confirmed by RHDV virus-specific RT-PCR targeting the VP60 gene with the expected band size of 398 bp for the five rabbits sampled. Our findings highlight the need for increased genomic surveillance of RHDV2 to track its origin, understand its diversity and to inform public health policy in Nigeria, and Sub-Saharan Africa.

scholarly journals Genetic analysis of some economic traits in a composite breed of domestic rabbits reared in a tropical environment

2014 ◽  
Vol 28 (2) ◽  
pp. 34-37 ◽  
Author(s):  
U.G. Sorhue ◽  
F.U.C. Mmereole ◽  
E.P. Irikefe-Ekeke ◽  
S.U. Nwakwo
Keyword(s):  
Genetic Analysis ◽  
Tropical Environment ◽  
Economic Traits ◽  
Domestic Rabbits

scholarly journals THE EFFECTS OF ROENTGEN RAYS ON CELL-VIRUS ASSOCIATIONS

1943 ◽  
Vol 78 (4) ◽  
pp. 285-304 ◽  
Author(s):  
William F. Friedewald ◽  
Rubert S. Anderson
Keyword(s):  
X Rays ◽  
Pathological Changes ◽  
Cellular Division ◽  
Papilloma Virus ◽  
X Ray ◽  
Crude Extracts ◽  
Domestic Rabbits ◽  
Roentgen Rays

The virus-induced papillomas of cottontail as well as domestic rabbits regress completely within a few weeks when exposed to 5,000 r of x-ray irradiation. The x-rays do not immediately kill the papilloma cells, but lead to death by inhibiting cellular division and producing pathological changes in the cells which then continue to differentiate. The virus associated with the growths, however, not only persists in undiminished amount during regression, but often an increased yield of it can be obtained on extraction. The fibroma virus in crude extracts or in vivo is inactivated by far less irradiation than the papilloma virus. 10,000 r destroys 90 per cent or more of the infectivity of the fibroma virus, whereas at least 100,000 r is required to inactivate 50 per cent of the papilloma virus in extracts containing about the same amount of protein. No variant of the papilloma virus or fibroma virus has been encountered as a result of the irradiation.

Scramble competition in newborn domestic rabbits for an unusually restricted milk supply

2005 ◽  
Vol 70 (5) ◽  
pp. 1011-1021 ◽  
Author(s):  
Amando Bautista ◽  
Marisol Mendoza-Degante ◽  
Gérard Coureaud ◽  
Margarita Martínez-Gómez ◽  
Robyn Hudson
Keyword(s):  
Scramble Competition ◽  
Milk Supply ◽  
Domestic Rabbits

scholarly journals A second rabbit kappa isotype.

1982 ◽  
Vol 156 (2) ◽  
pp. 585-595 ◽  
Author(s):  
A Benammar ◽  
P A Cazenave
Keyword(s):  
Light Chain ◽  
Immunoglobulin G ◽  
Antigenic Determinants ◽  
Gene Encoding ◽  
Genetic Studies ◽  
B Locus ◽  
Different Populations ◽  
Domestic Rabbits ◽  
Chain Type

Immunoglobulin G (IgG) from the rabbit strain Basilea was previously shown to contain two distinct populations of molecules one with light chain belonging to the known lambda isotype and the others to a new kappa-like L chain type. Alloantisera prepared against the Basilea IgG are directed against the kappa-like light chain (anti-bas antisera). All Basilea rabbits express kappa-like chains recognized by anti-bas sera, but IgG from other domestic rabbits did not react with these antisera. Genetic studies of wild rabbits belonging to different populations show that the bas+ phenotype could be found in heterozygous rabbits as well as those homozygous at the b locus. The gene encoding the bas+ light chain is closely linked to the b locus. Moreover, antigenic determinants recognized by anti-bas antibodies and antigenic determinants recognized by antibodies directed against allotypic determinants of the b series are located on distinct IgG molecules. These results show that there are two rabbit kappa isotypes: the kappa 1 isotype, bearing allotypic determinants of the b series, and the kappa 2 isotype, for which bas+ chain is one of the allotypic forms. The kappa 1 and kappa 2 isotypes are controlled by closely linked genes.

scholarly journals OBSERVATIONS ON THE RELATION OF THE VIRUS CAUSING RABBIT PAPILLOMAS TO THE CANCERS DERIVING THEREFROM

1936 ◽  
Vol 64 (3) ◽  
pp. 385-400 ◽  
Author(s):  
Peyton Rous ◽  
John G. Kidd ◽  
J. W. Beard
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Incubation Period ◽  
Squamous Cell ◽  
Sustained Activity ◽  
Experimental Inoculation ◽  
Natural Hosts ◽  
Carcinogenic Agents ◽  
Domestic Rabbits ◽  
Proliferating Cell

All the strains of the Shope virus thus far tested which give rise to vigorous, progressively enlarging papillomas in domestic rabbits, function as carcinogenic agents by way of these growths. The more pathogenic the virus as evidenced by the brevity of its incubation period and the vigor of the papillomas produced, the sooner and oftener does cancer occur. The number of virus entities contained in the inoculum notably influences the outcome, cancer appearing most frequently in those confluent, papillomatous masses which have resulted from the greatest concentration of the virus material under test. The papillomas experimentally induced by the ordinary inoculation methods are essentially aggregates of proliferating cell families, each the outcome of some primary cell-virus association. Some of these associations are followed more frequently by cancer than others are in the same animal. Cottontail rabbits, the natural hosts of the virus, are notably resistant to its sustained activity, as compared with domestic rabbits. Though often growing rapidly at first, the papillomas of cottontails soon become relatively inert in most cases, and they usually retrogress, and rarely undergo malignant change. In an instance here reported both a squamous cell carcinoma and a metastasizing sarcoma appeared at the base of some papillomas due to experimental inoculation, which had existed on the ears of a cottontail for nearly 2 years. The meaning of the phenomena is discussed.

scholarly journals Hematological Picture of Rabbits Immunized with Pseudomonas aeruginosa

2020 ◽  
Vol 44 ((E0)) ◽  
pp. 64-68
Author(s):  
Majid M. Mahmood ◽  
Ahmed N . Al-ani ◽  
Basil R . Razook
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Phosphate Buffer ◽  
T Test ◽  
Negative Group ◽  
Blood Picture ◽  
Sharp Fall ◽  
The Third ◽  
Group Control ◽  
Domestic Rabbits

The current study was established to find out the role of immunization of Pseudomonas aeruginosa-whole sonicated antigen in adult white fur domestic rabbits. To achieve this goal, fifteen rabbits were allocated into 3 groups, the first group was immunized with P. aeruginosa–whole sonicated antigen and challenged with viable pathogenic P. aeruginosa; the second group (control negative) was treated with phosphate buffer saline and the third group was injected with viable pathogenic P. aeruginosa (control positive). The results demonstrated increasing levels of the measured parameters blood picture (total WBCs, lymphocytes, and granulocytes, RBCs and hemoglobin concentrations) in the first group compared with control negative group (T test was used). In contrast, a sharp fall was noted in total thrombocytes (platelets) count in the first group compared with control negative group. It can be concluded that immunization with P. aeruginosa– whole sonicated antigen may consider as a potent reproducible effective immunogen model for experimental immunological studies in rabbits

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